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Chapter 7 Tobacco History of Tobacco Use Smoking can be traced back 600-900 A.D. Columbus received gifts of tobacco leaves from natives. Upon returning to Europe Columbus passed along seeds from the tobacco plant At first wealthy Europeans used tobacco and in time it became more affordable to most people. Tobacco shops were operating in London by the early1600s. Tobacco was used for medicinal purposes In 1828, nicotine was isolated and identified as poisonous and addictive so tobacco’s reputation as a medicinal agent declined In America tobacco was established as a valuable commodity and was used as a form of currency Until the late 1800s cigarettes were rolled by hand – the cigarette rolling machine was patented in 1883. The mass production of cigarettes cut the price in half. Cigarette smoking and tobacco use became more and more popular and as more evidence regarding the negative effects of tobacco use became more public it’s popularity began to decrease Extent of Tobacco Use In 2003, about one fourth of high school seniors had smoked within the previous 30 days More adult makes smoke than adult females Forms of Tobacco Cigarettes Chewing tobacco Pipe tobacco Cigars Clove Cigarettes Bidis Nicotine Tolerance and Dependence Experienced smokers and chewers build up tolerance quickly some in a matter of weeks Nicotine addicts exhibit symptoms characteristic of other forms of addiction Symptoms of Withdrawal Lower heart rate and blood pressure Difficulty in maintaining attention Heightened aggressiveness Insomnia Tremors Hunger Pharmacology of Tobacco Nicotine is one of 4,000 chemicals found in tobacco smoke Nicotine releases the norepinephrine which is responsible for stimulation Nicotine speeds up the blood flow to skeletal muscles and constricts blood vessels Nicotine is absorbed immediately and reaches the brain in as little as ten seconds The liver metabolizes almost all of the nicotine before it is excreted by the kidneys Physical Effects on the Individual Heart Disease – Increased Risk Respiratory Diseases – Increased Risk Cancer- Increased Risk Passive Smoke Passive smoke is referred to as involuntary or Environmental Tobacco Smoke (ETS) Passive smoke is blamed for 3,800 lung cancer deaths each year and accounts for 8,000 to 26,000 new asthma cases in children Rights of Smokers verses Nonsmokers Anti-Smoking legislation has been passed to prevent smoking in many public places and in enforcing a minimum age for purchasing cigarettes In the 1990s the U.S. Department of Labor proposed a ban on workplace smoking New York City banned tobacco advertisements on all city-owned billboards Airline passengers on all commercial flights within the United States were forbidden from smoking Amtrack passenger trains banned smoking in first class cars in the northeast corridor Legislation was passed that required the tobacco industry to pay $206 billion among all 50 states over a 25 year period(The Master Settlement Agreement) Cessation Techniques 90% of smokers in the United States who quit do so without any formal treatment program. Popular cessation techniques include Nicotine Gum Nicotine Patches Nicotine Inhalers Drug Therapy Aversive Techniques BehaviorModification Hypnosis Nicotine Gum, Patches, Inhalers Nicotine is contained in gums, patches, and inhalers. The nicotine is absorbed into the system and can result in a reduction in craving to tobacco Drug Therapy In 1997, the FDA approved Zyban for smoking cessation. Zyban is an antidepressant. How it works in reducing the craving for nicotine is unclear. Another drugs used in smoking cessation is clonidine Aversion Therapy An example of aversion therapy is rapid smoking where a person will smoke as many cigarettes as they can in a short time. The result will be a distaste (aversion) to smoking and may act as a motivator to stop smoking Behavior Modification This approach involves identifying behaviors linked to smoking and changing or modifying those behaviors. Hypnosis Hypnosis involves hypnotic suggestion and for some people the hypnotic suggestion will influence their behavior, including smoking behaviors Summary Smoking can be traced back to 500900 A.D. There are many forms of tobacco Nicotine tolerance and dependence have been documented Nicotine exerts multiple physical effects Passive smoke is a societal concern There are a wide variety of smoking cessation techniques