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On a notecard write your answer Bellringer: In one or two complete sentences describe what the following quote tells us about the origin of new life. Quote: “Fireflies rise from the morning dew, fish and frogs from a muddy stew, maggot worms from rotting meat and mice shall come from sweat and wheat.” Cell Theory and the Scientists Who Helped Shape It What is Spontaneous Generation?  the belief that living things can come from non-living things.  Was once thought to be true, but is now known to be false! How was it disproved?  the following scientists with their combined experiments proved the theory of spontaneous generation to be false & helped develop the Cell Theory. Scientists and the Cell Theory Who was… Francesco Redi? (1668)  scientist whose experiments proved maggots did not come from rotting meat. Who was…Robert Hooke? (1665)  used a compound microscope to look at cork (from bark of a tree) & he saw empty boxlike structures that he named “cells”. Who was…Antonie van Leewenhooke? (mid 1600’s)  used a simple microscope to look at pond water.  was the first to observe microorganisms in pond water. Who was…Matthias Schleiden? (1830’s)  studied numerous plant parts under the microscope and declared “ALL PLANTS ARE MADE OF CELLS!” Who was… Theodor Scwhann? (mid 1830’s)  Used a microscope to observe numerous animal tissues and declared “ALL ANIMALS ARE MADE OF CELLS!” Who was… Rudolf Virchow? (Mid 1830’s)  observed living cells dividing and declared “ALL CELLS COME FROM OTHER LIVING CELLS!” The Cell Theory  Major Contributors:  Matthias Schleiden  Theodor Schwann  Rudolph Virchow The Cell Theory 1. All living things are made of cells. 2. Cells are the basic units of structure and function in living things. 3. Living cells come only from other living cells. Characteristics of All Cells  A surrounding membrane  Cytoplasm – cell contents in thick fluid  Organelles – structures for cell function  Control center with DNA Cell Types  Prokaryotic  Eukaryotic Prokaryotic Cells • • • • • First cell type on earth Cell type of Bacteria and Archaea No membrane bound nucleus Nucleoid = region of DNA concentration Organelles not bound by membranes Eukaryotic Cells  Nucleus bound by membrane  Include fungi, protists, plant, and animal cells  Possess many organelles Plasma (Cell) Membrane Plasma Membrane  Contains cell contents  Double layer of phospholipids & proteins Phospholipids  Polar  Hydrophylic head  Hydrophobic tail  Interacts with water Movement Across the Plasma Membrane • A few molecules move freely – Water, Carbon dioxide, Ammonia, Oxygen • Carrier proteins transport some molecules – Proteins embedded in lipid bilayer – Fluid mosaic model – describes fluid nature of a lipid bilayer with proteins Membrane Proteins 1. Channels or transporters 3. Glycoproteins – Move molecules in one direction 2. Receptors – Recognize certain chemicals – Identify cell type 4. Enzymes – Catalyze production of substances Molecule Movement & Cells  Passive Transport  Active Transport  Endocytosis (phagocytosis & pinocytosis)  Exocytosis Passive Transport  No energy required  Move due to gradient  differences in concentration, pressure, charge  Move to equalize gradient  High moves toward low Types of Passive Transport 1. Diffusion 2. Osmosis 3. Facilitated diffusion Diffusion Molecules move to equalize concentration Osmosis  Special form of diffusion  Fluid flows from lower solute concentration  Often involves movement of water  Into cell  Out of cell Solution Differences & Cells solvent + solute = solution  Hypotonic  Solutes in cell more than outside  Outside solvent will flow into cell Isotonic Solutes equal inside & out of cell Hypertonic Solutes greater outside cell Fluid will flow out of cell Facilitated Diffusion  Differentially permeable membrane  Channels (are specific) help molecule or ions enter or leave the cell  Channels usually are transport proteins  (aquaporins facilitate the movement of water)  No energy is used Process of Facilitated Transport • Protein binds with molecule • Shape of protein changes • Molecule moves across membrane Active Transport • Molecular movement • Requires energy (against gradient) • Example is sodium-potassium pump Endocytosis  Movement of large material  Particles  Organisms  Large molecules  Movement is into cells  Types of endocytosis  bulk-phase (nonspecific)  receptor-mediated (specific) Process of Endocytosis • Plasma membrane surrounds material • Edges of membrane meet • Membranes fuse to form vesicle Forms of Endocytosis • Phagocytosis – cell eating • Pinocytosis – cell drinking Exocytosis  Reverse of endocytosis  Cell discharges material Vesicle moves to cell surface Membrane of vesicle fuses Materials expelled