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9/29/2014 Assessing Skin LesionsBenign or Malignant Inflammatory Disorders Helen Shim-Chang, M.D. Assistant Professor Dermatology and Dermatopathology Mount Sinai Medical Center New York, New York Lichen Simplex Chronicus Allergic contact dermatitis 1 9/29/2014 Psoriasis Psoriasis Lichen Planus Lichen Planus 2 9/29/2014 Perianal Lichen Planus Oral Lichen Planus Histology of Lichen Planus Lichen Sclerosis 3 9/29/2014 Lichen Sclerosis Lichen Sclerosis Lichen Sclerosis Histology of Lichen Sclerosis 4 9/29/2014 Topical steroid treatment of LS Complications of Lichen Sclerosis Chronic Lichen Planus- SCC Vesicular and Bullous Disorders 5 9/29/2014 Hailey-Hailey Disease Benign Familial Pemphigus Cicatricial Pemphigoid Pemphigus vulgaris vs Primary Herpes Simplex Cicatricial Pemphigoid 6 9/29/2014 Hypopigmentation: LSC vs Vitiligo Hyperpigmentation Vulvar Pigmentation Vulvar Melanosis 7 9/29/2014 Vulvar Melanosis Pigmented Lesions SNDerm 2000 Seborrheic Keratosis Benign Nevus 8 9/29/2014 Dysplastic NevusNevus with architectural disorder and cytologic atypia ABCDE’s of Melanoma • • • • • Dysplastic Nevus Malignant Melanoma A- Asymmetry along one or both axes B- Border irregularity C-Color variegation of red, blue, white, black D-Diameter of 6 mm (end of pencil eraser) E-Evolving 9 9/29/2014 Malignant Melanoma Malignant Melanoma Basal Cell Carcinoma Other Malignancies 10 9/29/2014 Basal Cell Carcinoma Vulvar papillomatosis looks like warts Squamous Cell Carcinoma HPV associated SCCBowenoid Papulosis SNDerm 11 9/29/2014 Bowenoid Papulosis Summary Extramammary Paget’s Disease Things can look alike…Thank you! • Many lesions of genital and non-genital skin can look alike. • Some clues are acute versus chronic, distribution, symmetry and possible involvement of other sites(mouth, eyes). • “If in doubt, cut it out”. A small biopsy can go a long way to a quick diagnosis and early treatment. 12