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Muscles Review Sheet What muscle layer surrounds an individual muscle fiber? What muscle layer surrounds a fascicle (bundle of muscle fibers) What muscle layer surrounds a bunch of fascicles? What muscle layer becomes the tendon? What is the MUSCLE FASCIA Endomycium Perimycium Epimycium (becomes the tendon) MUSCLE FASCIA is loose fibrous connective tissue on the outside of the muscle. It creates a slippery surface for muscles to rub against each other. What does it do? What is an aponeurosis? Name four types of muscles Which muscle type has long fibers that contract a long way but are relatively weak? Name 3 types of PENNATE MUSCLES What type of muscle has many short fascicles, is fairly strong, and insert on one side of a tendon? A modified tendon. It usually inserts just under the skin. This occurs in the palm and scalp. TYPES OF MUSCLES: PARALLEL PENNATE CONVERGENT CIRCULAR PARALLEL MUSCLE PENNATE (pinnate=feather) 1. UNIPENNATE 2. BIPENNATE 3. MULTIPENNATE UNIPENNATE Muscles Review Sheet What muscle type has fascicles that insert into the tendon from both sides? BIPENNATE What muscle type has fascicles in multiple bundles inserting on one tendon? MULTIPENNATE are the strongest; they are multi-tendon (biceps femoris; deltoid). Which muscle type is the strongest? What muscle type has more fibers than parallel, the fibers come together on the tip of a tendon, and contract a greater distance than pinnate? What does a Circular Muscle form? CONVERGENT MUSCLE Circular Muscle forms SPHINCTER. Muscles Review Sheet Define ORIGIN Define INSERTION Origin: The region which usually doesn’t move when the muscle contracts. Look at the biceps brachii; does the shoulder move when I bend my arm (insertion)? No; the shoulder = origin. Insertion: The point of attachment that moves; bend arm, radial tuberosity = attachment. What is the main muscle for a particular action called? What is the muscle that helps the agonist (primary mover)? AGONIST SYNERGIST ANTAGONIST SKELETAL SMOOTH CARDIAC What muscle does the opposite action of the prime mover? What are the 3 types of muscle cells? Which muscles are voluntary? Which are striated? 1) Skeletal 2) Skeletal and cardiac Where is skeletal muscle found and what does it do? Skeletal muscle is attached to bones and it moves the skeleton Where is cardiac muscle found and what structure does it have that the other muscle types do not have? Cardiac muscle is only in the heart. It has intercalated discs Smooth muscle is found in almost all organs. Where is smooth muscle found? What is a muscle stem cell called? MYOBLAST Why are there almost no muscle diseases? Because adults have myoblasts and because muscle can heal. What 2 things are needed for muscle contraction? NERVE SIGNAL and CALCIUM What is a MOTOR UNIT? A single neuron and all of the muscle fibers on which it synapses. Muscles Review Sheet What happens to muscles after much exercise? What happens to muscles after lack of use? Exercise HYPERTROPHY (Hyper=above normal) (growth in size); can happen in two ways: 1. Increase in number of myofibrils 2. Increase in number of myofilaments 3. Increase in size of individual myofibers NOTE: the number of myofibers does NOT increase Lack of use ATROPHY. What are characteristics of muscle atrophy? a) It is caused by lack of use b) myofilaments within the muscle decrease in size c) severe atrophy involves replacement of muscle fibers with connective tissue d) damaged nerve and immobilization in a cast can cause atrophy Atrophy does NOT involve loss of muscle cells What is MUSCULAR DYSTROPHY caused from? This is a genetic lack of a protein called DISTROPHIN. The muscle cell won’t contract = paralysis. What is the main symptom? When smooth muscle contracts around the intestines, the movement is called? What type of muscle has a series of gap junctions (for cell-to-cell communication) and desmosomes (that hold cells together) which join each cell? PERISTALSIS. Cardiac Muscle Fill in the table: Skeletal muscle Involuntary or voluntary? Striated or non-striated Where is it found? Smooth muscle Cardiac muscle Involuntary voluntary? Striated or nonstriated Where is it found? Skeletal muscle Voluntary Smooth muscle Involuntary Cardiac muscle Involuntary Striated Nonstriated Myometriu m of uterus, intestines, blood vessels, bladder, other organs Striated Inserts onto bones Myocardium of heart Muscles Review Sheet What is the normal state of a muscle, with some contraction? What is the molecular energy needed for MUSCLE CONTRACTION? What does the mitochondria need in order to produce this energy? What are MUSCLE SPASMS MUSCLE TONE ATP. The mitochondria need oxygen and the sugars that are in storage to produce this energy. Sudden and involuntary muscle contractions. Usually caused from overexertion. Needs heat and massage to increase circulation. You can avoid muscle spasms by stretching before and after activities. The amount of oxygen needed to replenish the supply following anaerobic demand. You experience oxygen debt when you continue to breathe heavily after exercising improved muscular strength, endurance, flexibility improved cardio-respiratory endurance increased bone density and strength How can you avoid them? What is OXYGEN DEBT? How do you know when you have it? Name 4 physiological benefits of exercise: Muscle myofibrils contain what two proteins? relief from depression and increased HDLs Actin and myosin What is it that contracts in muscle? What is the basic structural and functional unit of skeletal muscle? What is a single muscle cell called? What are the two types of myofilaments? Do actin and myosin shorten? When does the sliding filament mechanism begin? Which myofilament does calcium bind onto? Where is calcium stored for muscle contraction? To which myofilament does ATP attach in a muscle fiber? The sarcomere Sarcomere Muscle fiber or myofiber Actin (thin) and myosin (thick) No, they just slide past each other When calcium ions bind to the myofilament. The thin (actin filament) Sarcoplasmic reticulum ATP attaches to the myosin filament Muscles Review Sheet What is required for muscle relaxation? What neurotransmitter is used for contraction of skeletal muscle? What two proteins wrap around actin? What specific molecule on actin is the binding site for calcium? What covers the actin filament when muscle is relaxed? Which protein blocks the attachment site for myosin heads? What size motor unit will supply less strength and more precision? What is muscle tone? ATP Acetylcholine Tropomyosin and troponin Troponin Tropomyosin and troponin Tropomyosin Small motor unit What is HYPOtonia? What type of hypotonia is there? What group of disorders often present with HYPOtonia? What is hypertonia? What two types of HYPERtonia are there? How do you test for the presence of spasticity? What autoimmune disorder often presents with spasticity? What other three disorders often present with spasticity? The normal state of muscle, with some contraction. Not enough muscle tone Flaccidity Lower motor neuron diseases (certain spinal cord injuries and lesions, ALS/Lou Gehrig’s Disease) Excess muscle tone Spasticity and Rigidity Passively move their elbow quickly, and their muscle will tighten up Multiple sclerosis How do you test for clonus? The presence of clonus indicates what type of disorder? How can you test for the difference between an upper and lower motor neuron disorder? What is the most common cause of hyperreflexia? What generally causes muscle fasciculations? Does alcohol cause them? What is the most common cause of hyporreflexia? Cerebral palsy, certain spinal cord injuries and lesions, and stroke (upper motor neuron disorders) rapidly dorsiflexing the foot. If the foot then jerks 5 times or more, clonus is present. Upper motor neuron disorder (Cerebral palsy, spinal cord injury, and stroke) LMN disease will present with flaccidly (hypotonia), and UMN disease presents with spasticity (hypertonia) Spinal cord injury involving upper motor neurons Diarrhea Dehydration Fatigue Benadryl Alcohol does NOT cause them. It relaxes muscle Lower motor neuron disease Muscles Review Sheet What are the waste products of regular, aerobic respiration? How do we get rid of them? What is the waste product of anaerobic metabolism? How do we get rid of it? CO2 and water. We exhale them What stops us from being able to continue performing anaerobic metabolism (when you have to stop sprint running and catch your breath)? What is lacking in muscular dystrophy? Lactic acid. We breathe heavier to bring in oxygen, which converts lactic acid into glucose Glucose depletion and buildup of too much lactic acid. The protein, distrophin, which causes muscles to harden.