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PowerPoint® Lecture Slides Prepared by Patty Bostwick-Taylor, Florence-Darlington Technical College CHAPTER 6 The Muscular System © 2012 Pearson Education, Inc. The Muscular System •Muscles are responsible for all types of body movement •Three basic muscle types are found in the body •Skeletal muscle •Cardiac muscle •Smooth muscle © 2012 Pearson Education, Inc. © 2012 Pearson Education, Inc. © 2012 Pearson Education, Inc. Skeletal Muscle Characteristics •Most are attached by tendons to bones •Cells are multinucleate •Striated—have visible banding •Voluntary—subject to conscious control © 2012 Pearson Education, Inc. Connective Tissue Wrappings of Skeletal Muscle •Cells are surrounded and bundled by connective tissue •Endomysium—encloses a single muscle fiber •Perimysium—wraps around a fascicle (bundle) of muscle fibers •Epimysium—covers the entire skeletal muscle •Fascia—on the outside of the epimysium © 2012 Pearson Education, Inc. Muscle fiber (cell) Blood vessel Perimysium Epimysium (wraps entire muscle) Fascicle (wrapped by perimysium) Endomysium (between fibers) Tendon Bone © 2012 Pearson Education, Inc. Figure 6.1 Skeletal Muscle Attachments •Epimysium blends into a connective tissue attachment •Tendons—cord-like structures •Mostly collagen fibers •Often cross a joint due to toughness and small size •Aponeuroses—sheet-like structures •Attach muscles indirectly to bones, cartilages, or connective tissue coverings © 2012 Pearson Education, Inc. Smooth Muscle Characteristics •Lacks striations •Spindle-shaped cells •Single nucleus •Involuntary—no conscious control •Found mainly in the walls of hollow organs © 2012 Pearson Education, Inc. Mucosa Submucosa Circular layer of smooth muscle (longitudinal view of cells) Longitudinal layer of smooth muscle (cross-sectional view of cells) (a) © 2012 Pearson Education, Inc. Figure 6.2a Cardiac Muscle Characteristics •Striations •Usually has a single nucleus •Branching cells •Joined to another muscle cell at an intercalated disc •Involuntary •Found only in the walls of the heart © 2012 Pearson Education, Inc. Cardiac muscle bundles (b) © 2012 Pearson Education, Inc. Figure 6.2b Skeletal Muscle Functions •Produce movement •Maintain posture •Stabilize joints •Generate heat © 2012 Pearson Education, Inc. Microscopic Anatomy of Skeletal Muscle •Sarcolemma—specialized plasma membrane •Myofibrils—long organelles inside muscle cell •Sarcoplasmic reticulum—specialized smooth endoplasmic reticulum © 2012 Pearson Education, Inc. Sarcolemma Myofibril Light Dark (A) band (I) band Nucleus (a) Segment of a muscle fiber (cell) © 2012 Pearson Education, Inc. Figure 6.3a Microscopic Anatomy of Skeletal Muscle •Myofibrils are aligned to give distinct bands •I band = light band •Contains only thin filaments •A band = dark band •Contains the entire length of the thick filaments © 2012 Pearson Education, Inc. Z disc H zone Z disc Thin (actin) filament Thick (myosin) filament (b) Myofibril or fibril (complex organelle composed of bundles of myofilaments) © 2012 Pearson Education, Inc. I band A band I band M line Figure 6.3b Microscopic Anatomy of Skeletal Muscle •Sarcomere—contractile unit of a muscle fiber •Organization of the sarcomere •Myofilaments •Thick filaments = myosin filaments •Thin filaments = actin filaments © 2012 Pearson Education, Inc. Microscopic Anatomy of Skeletal Muscle •Thick filaments = myosin filaments •Composed of the protein myosin •Has ATPase enzymes •Myosin filaments have heads (extensions, or cross bridges) •Myosin and actin overlap somewhat •Thin filaments = actin filaments •Composed of the protein actin •Anchored to the Z disc © 2012 Pearson Education, Inc. Sarcomere Z disc M line Z disc Thin (actin) filament Thick (myosin) filament (c) Sarcomere (segment of a myofibril) © 2012 Pearson Education, Inc. Figure 6.3c Microscopic Anatomy of Skeletal Muscle •At rest, within the A band there is a zone that lacks actin filaments •Called either the H zone or bare zone •Sarcoplasmic reticulum (SR) •Stores and releases calcium •Surrounds the myofibril http://www.youtube.com/watch?feature=player_embedded&v=WVu W560nRII http://www.youtube.com/watch?feature=player_embedded&v=U2TS az8-yNQ © 2012 Pearson Education, Inc. Thick filament Bare zone Thin filament (d) Myofilament structure (within one sarcomere) © 2012 Pearson Education, Inc. Figure 6.3d Stimulation and Contraction of Single Skeletal Muscle Cells •Excitability (also called responsiveness or irritability)—ability to receive and respond to a stimulus •Contractility—ability to shorten when an adequate stimulus is received •Extensibility—ability of muscle cells to be stretched •Elasticity—ability to recoil and resume resting length after stretching © 2012 Pearson Education, Inc. The Nerve Stimulus and Action Potential •Skeletal muscles must be stimulated by a motor neuron (nerve cell) to contract •Motor unit—one motor neuron and all the skeletal muscle cells stimulated by that neuron © 2012 Pearson Education, Inc. Axon terminals at neuromuscular junctions Spinal cord Motor Motor unit 1 unit 2 Nerve Motor neuron cell bodies Muscle Axon of motor neuron Muscle fibers (a) © 2012 Pearson Education, Inc. Figure 6.4a Axon terminals at neuromuscular junctions Muscle fibers Branching axon to motor unit (b) © 2012 Pearson Education, Inc. Figure 6.4b The Sliding Filament Theory of Muscle Contraction •Activation by nerve causes myosin heads (cross bridges) to attach to binding sites on the thin filament •Myosin heads then bind to the next site of the thin filament and pull them toward the center of the sarcomere •This continued action causes a sliding of the myosin along the actin •The result is that the muscle is shortened (contracted) © 2012 Pearson Education, Inc. Actin Myosin Z H Z I A I (a) Z I © 2012 Pearson Education, Inc. (b) Z A I Figure 6.7a–b Contraction of Skeletal Muscle •Muscle fiber contraction is “all or none” •Within a skeletal muscle, not all fibers may be stimulated during the same interval •Different combinations of muscle fiber contractions may give differing responses •Graded responses—different degrees of skeletal muscle shortening © 2012 Pearson Education, Inc. Contraction of Skeletal Muscle •Graded responses can be produced by changing: •The frequency of muscle stimulation •The number of muscle cells being stimulated at one time © 2012 Pearson Education, Inc. Graded responses © 2012 Pearson Education, Inc. Muscle Response to Strong Stimuli •Muscle force depends upon the number of fibers stimulated •More fibers contracting results in greater muscle tension •Muscles can continue to contract unless they run out of energy © 2012 Pearson Education, Inc. Energy for Muscle Contraction •Initially, muscles use stored ATP for energy •ATP bonds are broken to release energy •Only 4–6 seconds worth of ATP is stored by muscles •After this initial time, other pathways must be utilized to produce ATP © 2012 Pearson Education, Inc. Energy for Muscle Contraction •Direct phosphorylation – 15 seconds •Anaerobic pathway – 40 seconds •Aerobic pathway - hours © 2012 Pearson Education, Inc. © 2012 Pearson Education, Inc. Muscle Fatigue and Oxygen Deficit •When a muscle is fatigued, it is unable to contract even with a stimulus •Common cause for muscle fatigue is oxygen debt •Oxygen must be “repaid” to tissue to remove oxygen deficit •Oxygen is required to get rid of accumulated lactic acid •Increasing acidity (from lactic acid) and lack of ATP causes the muscle to contract less © 2012 Pearson Education, Inc. Muscle Tone •Some fibers are contracted even in a relaxed muscle •Different fibers contract at different times to provide muscle tone and to be constantly ready © 2012 Pearson Education, Inc. Effect of Exercise on Muscles •Exercise increases muscle size, strength, and endurance •Aerobic (endurance) exercise (biking, jogging) results in stronger, more flexible muscles with greater resistance to fatigue •Makes body metabolism more efficient •Improves digestion, coordination •Resistance (isometric) exercise (weight lifting) increases muscle size and strength © 2012 Pearson Education, Inc. © 2012 Pearson Education, Inc. Figure 6.11a-b Muscles and Body Movements •Movement is attained due to a muscle moving an attached bone •Muscles are attached to at least two points •Origin •Attachment to an immoveable bone •Insertion •Attachment to a movable bone •During contraction, a skeletal muscle insertion moves toward the origin. © 2012 Pearson Education, Inc. Muscle contracting Origin Brachialis Tendon Insertion © 2012 Pearson Education, Inc. Figure 6.12 Types of Body Movements •Flexion •Decreases the angle of the joint •Brings two bones closer together •Typical of bending hinge joints like knee and elbow or ball-and-socket joints like the hip •Extension •Opposite of flexion •Increases angle between two bones •Typical of straightening the elbow or knee •Extension beyond 180° is hyperextension © 2012 Pearson Education, Inc. Types of Body Movements •Rotation •Movement of a bone around its longitudinal axis •Common in ball-and-socket joints •Example is when you move atlas around the axis (shake your head “no”) © 2012 Pearson Education, Inc. Types of Body Movements •Abduction •Movement of a limb away from the midline •Adduction •Opposite of abduction •Movement of a limb toward the midline © 2012 Pearson Education, Inc. Types of Body Movements •Circumduction •Combination of flexion, extension, abduction, and adduction •Common in ball-and-socket joints © 2012 Pearson Education, Inc. Special Movements •Dorsiflexion •Lifting the foot so that the superior surface approaches the shin (toward the dorsum) •Plantar flexion •Depressing the foot (pointing the toes) •“Planting” the foot toward the sole © 2012 Pearson Education, Inc. Special Movements •Inversion •Turn sole of foot medially •Eversion •Turn sole of foot laterally © 2012 Pearson Education, Inc. Special Movements •Supination •Forearm rotates laterally so palm faces anteriorly •Radius and ulna are parallel •Pronation •Forearm rotates medially so palm faces posteriorly •Radius and ulna cross each other like an X © 2012 Pearson Education, Inc. Special Movements •Opposition •Move thumb to touch the tips of other fingers on the same hand © 2012 Pearson Education, Inc. Types of Muscles •Prime mover—muscle with the major responsibility for a certain movement •Antagonist—muscle that opposes or reverses a prime mover •Synergist—muscle that aids a prime mover in a movement and helps prevent rotation •Fixator—stabilizes the origin of a prime mover © 2012 Pearson Education, Inc. (a) A muscle that crosses on the anterior side of a joint produces flexion* Example: Pectoralis major (anterior view) © 2012 Pearson Education, Inc. Figure 6.14a (b) A muscle that crosses on the posterior side of a joint produces extension* Example: Latissimus dorsi (posterior view) © 2012 Pearson Education, Inc. Figure 6.14b (c) A muscle that crosses on the lateral side of a joint produces abduction Example: Medial deltoid (anterolateral view) © 2012 Pearson Education, Inc. Figure 6.14c (d) A muscle that crosses on the medial side of a joint produces adduction Example: Teres major (posterolateral view) © 2012 Pearson Education, Inc. Figure 6.14d Naming Skeletal Muscles •By direction of muscle fibers •Example: Rectus (straight) •By relative size of the muscle •Example: Maximus (largest) © 2012 Pearson Education, Inc. Naming Skeletal Muscles •By location of the muscle •Example: Temporalis (temporal bone) •By number of origins •Example: Triceps (three heads) © 2012 Pearson Education, Inc. Naming Skeletal Muscles •By location of the muscle’s origin and insertion •Example: Sterno (on the sternum) •By shape of the muscle •Example: Deltoid (triangular) •By action of the muscle •Example: Flexor and extensor (flexes or extends a bone) © 2012 Pearson Education, Inc. Facial • Frontalis Facial • Temporalis • Orbicularis oculi • Zygomaticus • Masseter • Orbicularis oris Neck • Platysma • Sternocleidomastoid Thorax • Pectoralis minor Shoulder • Trapezius • Deltoid Arm • Triceps brachii • Biceps brachii • Brachialis Forearm • Brachioradialis • Flexor carpi radialis • Pectoralis major • Serratus anterior • Intercostals Abdomen • Rectus abdominis • External oblique • Internal oblique • Transversus abdominis Pelvis/thigh • lliopsoas Thigh • Sartorius • Adductor muscle Thigh (Quadriceps) • Rectus femoris • Vastus lateralis • Vastus medialis • Gracilis Leg • Fibularis longus • Extensor digitorum longus • Tibialis anterior Leg • Gastrocnemius • Soleus © 2012 Pearson Education, Inc. Figure 6.22 Neck • Occipitalis • Sternocleidomastoid • Trapezius Arm • Triceps brachii • Brachialis Forearm • Brachioradialis • Extensor carpi radialis longus • Flexor carpi ulnaris • Extensor carpi ulnaris • Extensor digitorum Shoulder/Back • Deltoid • Latissimus dorsi Hip • Gluteus medius • Gluteus maximus lliotibial tract Thigh • Adductor muscle • Hamstrings: Biceps femoris Semitendinosus Semimembranosus Leg • Gastrocnemius • Soleus • Fibularis longus Calcaneal (Achilles) tendon © 2012 Pearson Education, Inc. Figure 6.23 Deltoid muscle Humerus © 2012 Pearson Education, Inc. Figure 6.19 Posterior superior iliac spine IIiac crest Safe area in gluteus medius Gluteus maximus Sciatic nerve (b) © 2012 Pearson Education, Inc. Figure 6.20b Inguinal ligament Adductor muscles Sartorius Vastus lateralis (d) © 2012 Pearson Education, Inc. Figure 6.20d