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Detection, Visualization, and Identification of Lung Abnormalities in Chest Spiral CT Scans 3D CT Image Data Visualize Whole lung tissues Using VTK 8 mm Removing Background Making stochastic Model using Gibbs Markov Random Field Apply ICM using Genetic and EM algorithm Abnormality Detection System Visualize Abnormal Tissues Using VTK Registration Computer Vision Image Processing Laboratory www.cvip.uofl.edu Medical Imaging Types of medical Imaging 1. X-ray Imaging Advantage Cheap Disadvantage It is just a projection of an object Computer Vision Image Processing Laboratory www.cvip.uofl.edu Example of X-ray Imaging Computer Vision Image Processing Laboratory www.cvip.uofl.edu Example of X-ray Imaging Computer Vision Image Processing Laboratory www.cvip.uofl.edu 2. computed tomography (CT) Advantage 1. better Geometry of the scanned subject 2. Using CT we can build 3-D model of the scanned subject 3. Give high contrast between bones and soft tissues Computer Vision Image Processing Laboratory www.cvip.uofl.edu Disadvantage 1. Ct has harmful effect due to radiation dose (Xray) Computer Vision Image Processing Laboratory www.cvip.uofl.edu Example of CT Computer Vision Image Processing Laboratory www.cvip.uofl.edu 3. Magnetic Resonance Imaging (MRI) Advantage 1. Give high contrast of soft tissues Disadvantages 1. Does not preserve the geometry of the scanned subject if it is compared with CT Computer Vision Image Processing Laboratory www.cvip.uofl.edu Example of MRI Computer Vision Image Processing Laboratory www.cvip.uofl.edu 4. Ultrasound Imaging Advantage 1. Real Time Imaging 2. No harmful effect Computer Vision Image Processing Laboratory www.cvip.uofl.edu Example of Ultrasound Imaging Computer Vision Image Processing Laboratory www.cvip.uofl.edu Automated Lung Abnormality Detection System Visualize Whole lung tissues Using VTK 3D CT Image Data 8 mm Removing Background Making stochastic Model using Gibbs Markov Random Field Apply ICM using Genetic and EM algorithm Abnormality Detection System Visualize Abnormal Tissues Using VTK Registration Computer Vision Image Processing Laboratory www.cvip.uofl.edu System Design 1. Preprocessing Data Such as you can filter your images in order to reduce the noise 1. LPF 2. HPF 3. BPF 3. Median filter 4. Gaussian Filter Computer Vision Image Processing Laboratory www.cvip.uofl.edu Image 3 x 3 pixel Computer Vision Image Processing Laboratory www.cvip.uofl.edu 1. Remove the background Starting from the edge of the image, neighboring pixels are compared. Pixels having the same gray levels are removed (I.e., belong to the same region), while those differing are kept. Original Image 3x3 pixels Image 3 x 3 pixels after applying the algorithm Original image Image after removing background Computer Vision Image Processing Laboratory www.cvip.uofl.edu Chest Background Lung Computer Vision Image Processing Laboratory www.cvip.uofl.edu How To estimate the Initial Mean for Lung and Chest? Computer Vision Image Processing Laboratory www.cvip.uofl.edu Abnormal tissues CT Slice Contain Abnormal Tissues Computer Vision Image Processing Laboratory www.cvip.uofl.edu Slice_No. 32 Abnormal tissues Slice_No. 33 Computer Vision Image Processing Laboratory www.cvip.uofl.edu Abnormality Detection Criteria Each Ring Shape will take three ranks 1. Radial uniformity (R) 2. Position of the ring shape relative to the center of right or left lung edge (P) 3. Connectivity between different slices (C) Computer Vision Image Processing Laboratory www.cvip.uofl.edu Abnormality System detection Abnormal yes Remove the Normal Tissues Detecting ring shape Compute The Total Rank (R) for Each ring shape Tissues R> 2 No Normal Tissues Computer Vision Image Processing Laboratory www.cvip.uofl.edu a. Removing the normal tissues In order to remove the normal tissues of the lung, we will compute the histogram for each slice and search for its peak, and then remove all pixels beneath this peak. Before Removing normal Tissues Histogram of the CT slice After Removing normal Tissues Computer Vision Image Processing Laboratory www.cvip.uofl.edu c. Ranking 1. NR, measures the uniformity distribution of the edges. 2. NC, measures the connectivity that the pixel (x, y) appears in the same location in different slices 3. NP, each pixel given a rank NP reflecting its position relative to the center of the right lung or the left lung. Total Rank (N)= NR + NC + NP Computer Vision Image Processing Laboratory www.cvip.uofl.edu 4. Results (a) Original slice from a spiral CT scan of a patient (c) Desired tissues (b) Slice after removing the background (e) The isolated lungs Computer Vision Image Processing Laboratory www.cvip.uofl.edu (f) Bronchi, bronchioles and abnormal tissues (g) Abnormal tissues detected by our algorithm (h) Manual detection by expert doctor Computer Vision Image Processing Laboratory www.cvip.uofl.edu Building 3-D model We use VTK tool to build 3-D model for the whole lung tissues and abnormal tissues, bronchi, and bronchioles 3-D model for the whole lung tissues Computer Vision Image Processing Laboratory www.cvip.uofl.edu This Figure shows the abnormal tissues in the 3-D Computer Vision Image Processing Laboratory www.cvip.uofl.edu More Results Computer Vision Image Processing Laboratory www.cvip.uofl.edu