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2017 ENDOCRINE FELLOWS SERIES: TYPE 1 DIABETES CARE AND MANAGEMENT Tuesday, March 28, 2017 Rosen Centre Hotel Salon 9 & 10 9840 International Drive Orlando, FL Wednesday, March 29, 2017 Thursday, March 30, 2017 Hyatt Regency Orlando Orlando N 9801 International Dr Orlando, FL 32819 DIRECTLY ACROSS THE STREET FROM THE ROSEN CENTRE PROGRAM DIRECTORS Irl B. Hirsch, MD, University of Washington School of Medicine Linda M. Siminerio, RN, PhD, CDE, University of Pittsburgh Acknowledgement of Support This activity is supported by a grant from The Leona M. and Harry B. Helmsley Charitable Trust; Lilly USA LLC; and Medtronic Diabetes. PROGRAM AGENDA Tuesday, March 28, 2017 6:30–6:55 PM Dinner 6:55- 7:00 PM Welcome Irl B. Hirsch, MD University of Washington 7:00–7:45 PM Keynote Address: Cheating Destiny James S. Hirsch, Author 7:45–8:00 PM Q&A Wednesday, March 29, 2017 8:00–9:00 AM Registration and Breakfast 9:00–9:15 AM Opening Remarks 9:15–9:30 AM Case Presentation: Newly Diagnosed T1D Irl B. Hirsch, MD, University of Washington 9:30–10:15 AM Natural History/Pathogenesis/Immunopathology Bruce A. Buckingham, MD, Stanford School of Medicine 10:15–10:55 AM Strategies and Targets for Disease Modifying Therapies in T1D: A Look Into the Future of Endocrine Practice Carla J. Greenbaum, MD, Benaroya Research Institute 10:55–11:10 AM Q&A/Case Discussion 11:10–11:25 AM BREAK 11:25–11:40 AM Case Presentation: Managing the Sick Patient at Home Desmond A. Schatz, MD, University of Florida 11:40 AM–12:20 PM Hypoglycemia in Type 1 Diabetes Desmond A. Schatz, MD, University of Florida 12:20–12:35 PM Q&A/Case Discussion 12:35–1:45 PM Lunch with Faculty 1:45–2:00 PM Case Presentation: Patient in the ED Sandra I. Sobel, MD, University of Pittsburgh 2:00–2:40 PM T1DM Management in the Hospital Sandra I. Sobel, MD, University of Pittsburgh 2:40–3:20 PM Management of Hyperglycemic Crises in Adults Guillermo E. Umpierrez, MD, CDE, FACP, FACE, Emory University 3:20–3:35 PM Q&A/Case Discussion 3:35–3:50 PM BREAK 3:50–4:35 PM Breakout Sessions 1. Multiple Daily Injection (MDI) Room: Coral Spring I Mark A. Clements, MD, PhD, Children’s Mercy Kansas City 2. Continuous Subcutaneous Insulin Infusion (CSII) Insights Room: Coral Spring II Timothy S. Bailey, MD, AMCR Clinic 4:40–5:25 PM Breakout Sessions Repeat -----------------------------------------7:00–7:30 PM Dinner Room: Orlando M 7:30–8:15 PM Patient Engagement Margaret Eckel Peter J. Eckel Robert H. Eckel, MD 8:15–8:30 PM Q&A Thursday, March 30, 2017 7:30–8:00 AM Breakfast 8:00–8:55 AM Depression and Type 1 Diabetes William H. Polonsky, PhD, CDE, University of California Linda M. Siminerio, PhD, University of Pittsburgh 8:55–9:35 AM What I Wish I was Told When I Left my Fellowship Luisa A. Duran, MD, John Muir Health 9:35–9:50 AM Q&A/Case Discussion 9:50–10:05 AM BREAK 10:05–10:45 AM Use of Old and New Insulins Irl B. Hirsch, MD, University of Washington 10:45–11:25 AM T1DM and the Prevention and Treatment of Macrovascular Disease Robert H. Eckel, MD, University of Colorado 11:25 AM–12:05 PM The Endocrinologist’s Role in Screening/Management Microvascular Disease Janet B. McGill, MD, Washington University in St. Louis 12:05–12:20 PM Q&A/Case Discussion 12:20–1:30 PM Lunch with Faculty Discussion: Continuous Glucose Monitoring 1:30–2:15 PM Meet-The-Professor (MTP) Sessions 1. Realistic Nutrition Strategies for People with Type 1 Diabetes Room: Coral Spring I Alison B. Evert, MS, RD, CDE, University of Washington 2. Strategies for Diabetes Management with Intense Physical Activity Room: Coral Spring II Michael C. Riddell, MD, York University (Canada) 2:20–3:05 PM MTP Sessions Repeat 3:05–3:20 PM BREAK 3:20–4:00 PM Transition from Pediatric to Adult Care Linda M. Siminerio, PhD, University of Pittsburgh 4:00–5:15 PM Clinical Trials: How to Interpret Study Findings Roy W. Beck, MD, PhD, University of South Florida 5:15–5:30 PM Closing Remarks FACULTY Program Directors Irl B. Hirsch, MD; University of Washington Sch of Med Linda M. Siminerio, PhD; University of Pittsburgh Diabetes Institute Presenters Timothy S. Bailey, MD, FACE, CPI; AMCR Institute Inc. Roy W. Beck, MD, PhD; Jaeb Center for Health Res/University of Florida Bruce A. Buckingham, MD; Stanford School of Medicine Mark A. Clements, MD, PHD, CPI; Children’s Mercy Kansas City Luisa A. Duran, MD; John Muir Health Margaret Eckel Peter J. Eckel Robert H. Eckel, MD; University of Colorado Alison B. Evert MS, RD, CDE; University of Washington Carla J. Greenbaum, MD; Benaroya Research Institute James S. Hirsch; Author Janet B. McGill, MD; University of Washington William H. Polonsky PhD, CD; Behavioral Diabetes Institute Michael C. Riddell, MD; York University (Canada) Desmond A. Schatz, MD; University of Florida College of Medicine Sandra I. Sobel, MD; University of Pittsburgh Guillermo E. Umpierrez, MD; Emory University ACCREDITATION STATEMENT The Endocrine Society is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The Endocrine Society has achieved Accreditation with Commendation. The Endocrine Society designates this live activity for a maximum of 16.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. LEARNING OBJECTIVES Upon completion of this educational activity, learners will be better able to: • Differentially diagnose T1D in youth and assess the familial risk of developing T1D • Utilize patient education and counseling to motivate patients and their caregivers and promote adherence • Apply current clinical information to set appropriate blood glucose targets taking into consideration a patient’s lifestyle, age and condition • Evaluate clinical practice guidelines on the prevention, screening and management of comorbidities • Explain the neurological consequences of hypoglycemia and hyperglycemia and recognize potential causes • Recognize special considerations in the management of diabetes in a trauma or in-patient setting • Discuss the important of individualized nutrition plans and goals for patients with T1D • Discuss the potential risks and benefits associated with emerging therapies for diabetes TARGET AUDIENCE This continuing medical education activity should be of substantial interest to pediatric and adult endocrine fellows who are interested in the treatment and care of patients with type 1 diabetes. STATEMENT OF INDEPENDENCE As a provider of continuing medical education (CME) accredited by the Accreditation Council for Continuing Medical Education, the Endocrine Society has a policy of ensuring that the content and quality of this educational activity are balanced, independent, objective, and scientifically rigorous. The scientific content of this activity was developed under the supervision of the Endocrine Society's Special Programs Committee (SPC). The commercial supporter(s) of this activity have no influence over the planning of this CME activity. DISCLOSURE POLICY The faculty, committee members, and staff who are in position to control the content of this activity are required to disclose to the Endocrine Society and to learners any relevant financial relationship(s) of the individual or spouse/partner that have occurred within the last 12 months with any commercial interest(s) whose products or services are related to the CME content. Financial relationships are defined by remuneration in any amount from the commercial interest(s) in the form of grants; research support; consulting fees; salary; ownership interest (e.g., stocks, stock options, or ownership interest excluding diversified mutual funds); honoraria or other payments for participation in speakers' bureaus, advisory boards, or boards of directors; or other financial benefits. The intent of this disclosure is not to prevent CME planners with relevant financial relationships from planning or delivery of content, but rather to provide learners with information that allows them to make their own judgments of whether these financial relationships may have influenced the educational activity with regard to exposition or conclusion. The Endocrine Society has reviewed all disclosures and resolved or managed all identified conflicts of interest, as applicable. The faculty reported the following relevant financial relationship(s) during the content development process for this activity: Timothy S Bailey, MD: Consultant, Bayer, BD, Calibra, Lilly, Medtronic, Novo Nordisk, Sanofi; Researcher, Versartis, Yofimeter; Speaker, Insulet, Medtronic, Novo Nordisk, Sanofi Bruce A Buckingham, MD: Advisory Board Member, Animas, Halozyme, Novo Nordisk, Sanofi; Advisory Board Member and Investigator, Convatec, Medtronic, Tandem; Investigator, Bayer, Dexcom Mark A Clements, MD: Advisory Group Member, Glooko/Diasend Robert Eckel, MD: Consultant, Merck & Co. Novo Nordisk, Consultant; Sanofi; Independent Contractor, UniQure; Researcher, Ionis Alison Evert, MS: Medical Advisory Board Member, Seseonice Carla Greenbaum, MD: Consultant, Bristol-Myers Squibb, Pfizer, Inc.; Principal Investigator, Jansen Pharmaceuticals, Novo Nordisk Irl B. Hirsch, MD: Consultant, Abbott laboratories, Roche Diagnostics, Intarcia, Valeritas Janet B McGill, MD: Advisory Group Member, Jansen Pharmaceuticals, Merck & Co.; Committee Member, Boehringer-Ingelheim; Speaker, Jansen Pharmaceuticals William H Polonsky PhD: Consultant, Abbott Laboratories, Astra Zeneca, Dexcom, Eli Lilli & Company, Novo Nordisk, Roche Diagnostics Guillermo E Umpierrez, MD: Consultant, Ad Hoc, Sanofi; Principal Investigator, Astra Zeneca, Merck & Co., Sanofi The following faculty reported no relevant financial relationship: Roy W. Beck, MD; Luisa A. Duran, MD; Margaret Eckel; Peter J. Eckel; James S. Hirsch; Michael Riddell, MD; Desmond A. Schatz, MD; Sandra Sobel, MD Endocrine Society staff associated with the development of content for this activity reported no relevant financial relationships. DISCLAIMER The information presented in this activity represents the opinion of the faculty and is not necessarily the official position of the Endocrine Society. Use of professional judgment: The educational content in this activity relates to basic principles of diagnosis and therapy and does not substitute for individual patient assessment based on the health care provider’s examination of the patient and consideration of laboratory data and other factors unique to the patient. Standards in medicine change as new data become available. Drugs and dosages: When prescribing medications, the physician is advised to check the product information sheet accompanying each drug to verify conditions of use and to identify any changes in drug dosage schedule or contraindications. POLICY ON UNLABELED/OFF-LABEL USE The Endocrine Society has determined that disclosure of unlabeled/off-label or investigational use of commercial product(s) is informative for audiences and therefore requires this information to be disclosed to the learners at the beginning of the presentation. Uses of specific therapeutic agents, devices, and other products discussed in this educational activity may not be the same as those indicated in product labeling approved by the Food and Drug Administration (FDA). The Endocrine Society requires that any discussions of such “off-label” use be based on scientific research that conforms to generally accepted standards of experimental design, data collection, and data analysis. Before recommending or prescribing any therapeutic agent or device, learners should review the complete prescribing information, including indications, contraindications, warnings, precautions, and adverse events. PRIVACY AND CONFIDENTIALITY STATEMENT The Endocrine Society will record learner's personal information as provided on CME evaluations to allow for issuance and tracking of CME certificates. The Endocrine Society may also track aggregate responses to questions in activities and evaluations and use these data to inform the ongoing evaluation and improvement of its CME program. No individual performance data or any other personal information collected from evaluations will be shared with third parties. ACKNOWLEDGEMENT OF COMMERCIAL SUPPORT This activity is supported by educational grants from The Leona M. and Harry B. Helmsley Charitable Trust; Lilly USA, LLC, and Medtronic Diabetes. AMA PRA CATEGORY 1 CREDIT™ (CME) INFORMATION The Endocrine Society designates this live activity for a maximum of 16.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. To receive a maximum of 16.5 AMA PRA Category 1 Credits™, participants must complete the activity evaluation online at education.endocrine.org/T1D2017. Once completed, you will be able to save or print a CME certificate. For questions about content or obtaining CME credit, please contact the Endocrine Society at education.endocrine.org/contact PARTICIPANTS Sandra Aleksic, MD Albert Einstein College of Medicine Bronx, NY sandraleksic@yahoo.com Britany F. Epstein, BSDO University of Sample Gainesville, FL britanyep@pcom.edu Lina Alkhaled, MD Case Western Reserve University Cleveland, OH lina.alkhaled@hotmail.com Alex N. Gonzalez Bossolo, MD San Juan City Hospital San Juan, PR alexn521@gmail.com Sumeet Arora, MBBS SUNY Downstate Medical Center Brooklyn, NY drsumeetarora@gmail.com Jayashree Gowda, MD University of Iowa Iowa City, IA jtgowda@gmail.com Muhammad F. Arshad, MBBS South Yorkshire Deanery South York, UK dr.fahadarshad@live.com Deepak C. Gupta, MD LLRM Medical College Uttar Pradesh, India deepak_fortis@yahoo.com Mohini V. Bollineni, MD Suny Upstate Syracuse, NY mbollineni@hotmail.com Oksana Hamidi, DO Mayo Clinic Rochester, MN oksana.hamidi@gmail.com Kristin Childress, BSMD Los Angeles County Harbor Torrance, CA kchildress@labiomed.org David W. Hansen, MD, MPH Indiana University Carmel, IN dwhansen@iu.edu Alessandra Cocca, MD Second University of Naples Naples, Italy alessandracocca@gmail.com Inga Harbuz-Miller, MD University of Missouri Columbia, MO inga.harbuzmiller@gmail.com Ladan Davallow, MD University of Virginia Charlottesville, VA ldg7f@virginia.edu Rim Hasan, MD University of Arkansas for Medical Science (UAMS) Little Rock, AR mail2reem@gmail.com Bryan Davis, DO Rowan University Stratford, NJ bfdavisdo@gmail.com Victoria R. Hudspeth, MD University of North Carolina at Chapel Hill, Chapel Hill, NC tori.hudspeth@gmail.com Anna Isfort, MD National Capital Consortium Bethesda, MD anna.isfort@gmail.com M. Romina Lomonoco, MD University of Florida Gainesville,FL rlomonaco@ufl.edu Amer Issa, MD Wayne State University Detroit, MI issa.aamer@yahoo.com Sravahthi Madala, MD Brown University Providence, RI sravanthi.madala@lifespan.org Jennifer J. Iyengar, MD University of Michigan Ann Harbor, MI jmacd@umich.edu Mehmet S. Marangoz, MD Louisiana State University New Orleans, LA mehmetsmarangoz@gmail.com Sina Jasim, MD Mayo Clinic Rochester, MN jasim.sina@mayo.edu Shilpa Mehta, MD New York University New York, NY shilpa.mehta@nyumc.org Shabana p. Kalladi, MD Virginia Commonwealth University Richmond, VA shabana.unnikamu@gmail.com Mahnaz Mellati, MD University of Washington Seattle, WA mahnazmellati@yahoo.com Jamolkhon K. Kayumov, MBBS, MD Tashkent Medical Academy Tashkent, Uzbekistan dr.kayumov@gmail.com Christopher M. Mulla, MD, MS Harvard Medical School Boston, MA cmulla@umich.edu Yulia Klitsunova, MD Zaporizhia Medical Academy Zaporizhia, Ukraine uskovajulia@ya.ru Juan M. Munoz Pena, MD Tufts Medical Center Boston, MA juanmanuel_munoz@hotmail.com Juan J. Lado, MD Children's Hospital of Philadelphia Philadelphia, PA ladoj@email.chop.edu Pamela Ohri, MD University of Connecticut Farmington, CT ohri@uchc.edu Allison LaRoche, MD, MPH University of Washington Seattle, WA allison.laroche@seattlechildrens.org Manish G. Raisingani, MD New York University New York, NY manishraisingani@hotmail.com Arpana Rayannavar, MD Children's Hospital of Philadelphia Philadelphia, PA rayannavaa@email.chop.edu Alejandro Santos Leal, MD Medstar Union Memorial Hospital Baltimore, MD alsale@hotmail.com Sulay Shah, MD Tulane University Medical Center New Orleans, LA dr_sulayhshah@yahoo.com Rahul Sharma, MD University of Wisconsin Madison, WI rsharma2@uwhealth.org Muhammad Talha, MD University of Arkansas Little Rock, AR doctalha@hotmail.com Angela R. Verardo, MD Johns Hopkins University Philadelphia, PA averard1@jhmi.edu Justin Yoon, MD Brown University Providence, RI justin.j.yoon@gmail.com Wenyi Zhang, MD Harbor UCLA Medical Center Torrance, CA wzhang@labiomed.org
