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Regulation and Homeostasis in the Human Body: Overview How do Humans and other complex mammals maintain homeostasis? They must carry out all needed life functions in a coordinated way. What does our species need to accomplish? Growth Repair of injuries Get energy Get building materials Get rid of waste Keep away disease Respond to changing environment Reproduce Eleven Body Systems work together to maintain homeostasis and carry out these tasks: 1. Nervous System 2. Endocrine System 3. Lymphatic System 4. Circulatory System 5. Respiratory System 6. Digestive System 7. Excretory System 8. Skeletal System 9. Muscular System 10. Integumentary System 11. Reproductive System 1. Nervous System: Structures: Brain, Spinal Cord, Peripheral Nerves, Neurons (Cells of nervous system) Functions: Coordinates the body’s response to changes to internal and external environment 2. Endocrine System – Hormone System Structures: Glands Hypothalmus, pituitary, thyroid, parathyroids, adrenals, pancreas, ovaries (in females), testes (in males) Functions: Produce Hormones. Controls growth, development, metabolism, and reproduction 3. Lymphatic System – Immune System Structures: White blood cells, thymus, spleen, lymph nodes, lymph vessels Function: Helps protect the body from disease; collects fluid lost from blood vessels; returns the fluid to the circulatory system 4. Circulatory System Structures: Heart, Blood vessels, blood Functions: Brings oxygen, nutrients, and hormones to cells; fights infection; regulates body temperature 5. Respiratory System Structures: Nose, pharynx, larynx, trachea, bronchi, bronchioles, lungs Functions: Provides oxygen needed for cellular respiration and removes carbon dioxide from body 6. Digestive System Structures: Mouth, pharynx, larynx, esophagus, stomach, liver, pancreas, small and large intestines, Function: Breaks down foods into simple molecules that can be used by the body for respiration and building cells 7. Excretory System Structures: Skin, lungs, kidneys (nephrons), ureters, urinary bladder, urethra Functions: Removes waste products of metabolism from the body 8. Skeletal System Structures: Bones, cartilage, ligaments, tendons Functions: Supports the body; protects internal organs; allows movement; stores mineral reserves; provides a site for blood formation 9. Muscular System Structures: Skeletal muscle, smooth muscle, cardiac muscle Function: Works with skeletal system to produce voluntary movement; helps circulate blood and move food through the digestive system 10. Integumentary System (Skin) Structures: Skin, Hair, Nails, Sweat and Oil Glands Functions: Serves as a barrier against infection and injury; Helps to regulate temperature; Protects against UV light 11. Reproductive System Structures: Female- Uterus, Fallopian tubes, ovary, cervical canal, cervix, vagina Male – Penis, Vas Deferens, Prostate, Epididymis, Testes, Scrotal Sac, Seminal Vesicle Function: Produces reproductive cells; in females nurtures and protects developing embryo Support and Motion Functions of the SKELETAL AND MUSCULAR SYSTEM How does the human body move from place to place and have the ability to run, blink or build things? These things are all made possible by the skeletal and muscular systems. A. Skeletal Skull System There are 206 bones in the adult human body. These bones provide a system of supports and levers on which muscles can produce movement Sternum Ribs Vertebral column Clavicle Scapula Humerus Radius Pelvis Ulna Carpals Metacarpals Phalanges Femur Patella Fibula Tibia Tarsals Metatarsals Phalanges Bones are a solid network ofStructure living cells and Figure 36-3 The of Bone protein fibers that are surrounded by calcium deposits. Bones contain blood vessels and cavities containing marrow. Red marrow produces red blood cells, white blood cells and platelets Bone Marrow Joints are placesFigure where one bone attaches to and another. 36-4 Freely Movable Joints Their Movements Each Section type36-1 of joint is designed to allow movement without damaging the other bones. Joints in the skull allow no movement, joints in the spine allow a small amount of movement and those shown below allow movement in one or more directions. Clavicle Joint Ball-and-Socket Pivot Joint Elbow Hinge Knee Joint Saddle Joint Section 36-1 Knee Joint Ligaments are a tough connective tissue that attach bones to bones Tendons are connective tissue which attach bones and muscles to allow bones to move Muscle Tendon Femur Patella Bursa Ligament Cartilage Fat Fibula Tibia B. The Muscular System More than 40% of the average human is muscle. Muscles are involved in both voluntary actions and involuntary actions. Three types of muscles cells are: •Skeletal – Attached to bones for voluntary actions and controlled by the central nervous system •Smooth – Found in the digestive tract and the blood vessels to move food and blood. Control involuntary actions (you do not decide for them to work) •Cardiac – Heart muscle cells are involuntary. Figure 36-7 Skeletal Muscle Structure Skeletal muscles are made up of clusters of filaments Section 36-2 of proteins known as actin and myosin which control muscle contraction and relaxation Nervous system cells known as motor neurons are attached to skeletal muscle cells to control the voluntary movement. Threadlike Nerve or neuron Axon or junction Figure 36-8 Muscle Contraction During Muscle contraction Actin filaments slide over myosin filaments shrinking the muscle Energy for muscle contraction is supplied by ATP Figure 36-11 Opposing Muscle Pairs Skeletal Section 36-2muscles work in opposing pairs. When one muscle contracts, the other relaxes. Movement Movement Triceps (contracted) Biceps (relaxed) Biceps (contracted) Triceps (relaxed) Nutrition and Waste Removal How does the human body take in required nutrients and get rid of wastes? The Digestive and Excretory Systems are responsible for bringing in food and getting rid of the leftovers. Overview of Nutrients Food supplies the raw materials for building molecules your body needs, such as: • enzymes • Lipids in cell membranes • DNA Food contains 45 substances your body needs but cannot manufacture. The nutrients your body needs are water, carbohydrates, fats, proteins, vitamins and minerals. WATER – Most of the bodies reactions take place in water. Humans need an average of 1 liter of water a day. Dehydration causes many problems throughout the body. CARBOHYDRATES – Sugars and starches are used by the body to provide the simple sugars needed for Respiration (energy) FATS- Deposits of fats protect body organs, insulate the body and store energy, make up cell membranes and coat the nervous system cells PROTEINS – Supply the raw materials for growth and repair in the form of enzymes VITAMINS – Organic molecules that work with enzymes to control body processes. MINERALS – Inorganic nutrients that are needed in small amounts. Calcium is needed to build bones, Iron is needed for red blood cells. Food Guide Pyramid A Balanced Diet Fats Sugars C. The Digestive System Mouth Pharynx Salivary Glands Esophagus Liver Gallbladder Stomach Pancreas behind stomach Large Intestine Small Intestine Rectum The Process of Digestion: The path of food Each organ of the digestive system helps convert foods into simpler molecules that can be absorbed and used by the cells of the body. Teeth – Cut, Crush and tear food Salivary glands – Moisten food to make it easier to chew and pass through the system, enzymes break down starches Esophagus – Tube from mouth to stomach connected by Pharynx. Works by contraction of the smooth muscles known as peristalsis. Stomach – Muscular sac that churns and mixes food with acid As food leaves the stomach it travels into the small intestine the doudenum, and it mixes with Sectionthrough 38-2 with enzymes and digestive fluids from the liver, gallbladder and pancreas. Liver Gallbladder Doudenum Bile Duct Pancreas Chemicals from the pancreas breakdown . carbohydrates, proteins, lipids and nucleic acids. In addition chemicals from the pancreas produce substances which neutralize stomach acid. If the acid travels too far without being neutralized it will change the shape of enzymes and cause problems in the body. The Liver makes bile which acts like a detergent to break down fat. The gall bladder is a storage area for the bile The small intestine absorbs nutrients from the digestive systems and transfers many of the nutrients Section 38-2 to the circulatory system. The small intestine is lined with small fingerlike projections known as villi which designed to have a large surface area for this task. Small Intestine Villus Large intestine (Colon) Food that enters the large intestine is nutrient-free. Usable nutrients have been absorbed leaving water and undigestible substances. The large intestine removes water from the waste. Once water is eliminated the solid waste passes out of the body through the rectum. The appendix is located just below the entry to the large intestine. In many animals it helps digest difficult materials such as cellulose. In humans the appendix is not used for any purpose in digestion. When it gets infected it is removed. D. Excretory System: In the process of obtaining nutrients and carrying out chemical reactions the human body produces wastes (CO2, Urea, Salts). If some of these wastes are not removed they could threaten homeostasis. Excess chemicals that are not toxic also need to be removed. The skin, lungs and kidneys all function to get rid of excess or harmful products produced in the body. Kidneys contain millions of small filters called Section 38-3 nephrons , which filter your entire blood supply every 45 minutes. Filtration takes place because blood pressure forces water, salt, glucose, amino acids and urea into structures known as Bowman’s capsules. (Protein and Blood are too large to enter) Kidney Nephron Bowman’s Capsule Processes of osmosis and active transport filter the useful materials from the waste (urine). Substances your body needs to keep are returned to the blood stream. Substances your body needs to get rid of are passed from the renal tubes to the urinary bladder. Vein Kidney Ureter Urinary Bladder Urethra Artery