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Chapter 8 – Muscular System I. II. A. Introduction A. All movements require muscles to contract using ATP (chemical energy) - moving blood, urine, & sweat - producing heat to warm the body B. C. Each muscle is an organ made of blood & tissues (muscle, connective, & nervous) Pg. 190 D. B. Cardiac 1. involuntary muscle of the heart 2. doesn’t fatigue 3. have striations & intercalated disks – join cells & transmit contraction from cell to cell heart cells beat spontaneously * This arrangement allows parts to move independently 8-3 C. Pg. 192 There are 3 layers of connective tissue within each muscle 1. epimysium: closely surrounds a skeletal muscle 2. perimysium: separates muscle into bundles called fascicles 3. endomysium: surrounds each muscle fiber (cell) Pg. 190 8-2 III. Structure of a Muscle Fiber (cell) Cell Membrane = Sarcolemma Cytoplasm = Sarcoplasm, containing: 1. many nuclei & mitochondria 2. thin proteins called myofibrils, which are responsible for muscle contraction a) thin one is actin 8-4 b) thick one is myosin A layer of fibrous connective tissue called fascia surrounds & separates each muscle - it extends beyond muscles to form tendons that are fused to the periosteum of bones Three types of muscle exist skeletal, smooth, & cardiac 8-1 A. B. B. Connective Tissue Sarcoplasmic Reticulum – channels surrounding each myofibril that transport chemicals Transverse (T) Tubules – channels that pass through the core of a muscle fiber to transport calcium & ATP IV. Types of Muscle A. Smooth Pg. 122-123 1. 2. Pg. 192 3. * SR 8 - 5 & T-tubules activate muscle contraction when the fiber is stimulated C. Skeletal 1. voluntary muscles used for movement that are attached to bones 2. do fatigue 3. have striations 8-6 V. involuntary muscles lining organs (stomach, bladder, uterus, blood vessels) do peristalsis (wavelike contractions) to move substances through the lumen these muscles surround fibers are slower to contract & relax, but resistant to fatigue Skeletal Muscles of the Human Body A. Muscles attach to bones at 2 sites 1. Origin = immovable end of a muscle 2. Insertion = movable end of a muscle * Contraction always occurs to move point of insertion towards point of origin * Pg. 122-123 Pg. 122-123 8-7 8-8 8-9 Pg. 204 1 B. C. Interaction of Skeletal Muscles 1. In a group of muscles, the one doing the majority of the work is the prime mover or agonist 2. Muscles that resist the action of the prime mover are antagonists 3. Assisting the prime mover are muscles called synergists Skeletal Muscles to know (pg. 205) 1. Facial Expressions a) Epicranius (Frontalis & Occipitalis) – elevates eyebrows b) Orbicularis oris – closes & protrudes lips c) Orbicularis oculi – closes eyes d) Platysma – depresses lower lip (pg 207) e) Zygomaticus – “smile” muscle; elevates corner of mouth 2. Mastication a) Masseter – elevates & protracts mandible b) Temporalis – elevates & retracts mandible Prime Mover Synergists 8 - 10 8 - 11 3. Neck Sternocleidomastoid – Each flexes & rotates the head and neck forward & laterally 4. Trunk a) Trapezius – elevates & depresses scapula b) Latissimus dorsi – extends arm at shoulder, adducts & medially rotates arm c) Pectoralis major – flexes arm at shoulder, adducts and medially rotates arm d) Rectus abdominis – Compresses abdomen, flexes vertebral column e) External oblique – Compresses abdomen, flexes and rotates vertebral column 8 - 13 VI. Muscles & The Nervous System A. Neuromuscular Junction - site where a motor neuron (nerve cell) and a muscle fiber functionally, but not physically connect 5. Arm a) Deltoid – Flexes arm at shoulder, adducts and medially rotates arm b) Biceps brachii – Flexes forearm at elbow, laterally rotates (supinates) forearm and hand c) Triceps brachii – Extends forearm at elbow 6. Lower Leg a) Tibialis anterior – dorsiflexion b) Soleus – plantar flexion c) Gastrocnemius – plantar flexion & flexion 8 - 14 of leg at knee B. Pg. 193 8 - 16 1. The end of the muscle fiber forms a motor end plate 2. The motor neuron stores chemicals called neurotransmitters 8 - 12 C. 7. Upper Leg a) Gluteus maximus – Extends thigh at hip b) Gluteus medius – Abducts thigh, rotates thigh medially c) Sartorius – Flexes leg at knee, flexes thigh at hip, abducts thigh, rotates thigh laterally, rotates leg medially d) Gracilis – Abducts & medially rotates thigh e) Quadriceps – extends leg at knee: Rectus femoris, Vastus medialis, Vastus lateralis, Vastus intermedius f) Hamstrings – flexes leg at knee: 8 - 15 Biceps femoris, Semitendinosus, Semimembranosus Muscular Responses 1. Threshold Stimulus – a muscle fiber remains unresponsive until a certain strength of stimulation is applied 2. Calcium ions cause Actin and Myosin to slide together, causing a contraction called a twitch. 3. During a twitch, a fiber pulls at its attachment, followed by relaxation Motor Units 1. A whole muscle can create more force if more muscle fibers are 8 - 17 involved in the contraction 8 - 18 Pg. 201 2 1. 2. 3. 4. 5. 8 - 19 C. Motor Units are 1 motor neuron and the 2-3 muscle fibers it controls These are functional units, because an impulse to the motor neuron will cause all fibers in the unit to contract at the same time (“All or None Response”) Some units are more sensitive to stimulation than others, and thus have a lower threshold stimulus At lower thresholds, fewer sensitive units contract; At higher intensities of stimulation, more motor units cause contraction Recruitment: increase in # of motor units activated during a contraction Relaxation – the lengthening of a muscle from its point of origin 1. Acetylcholine is decomposed by Acetylcholinesterase (ATP needed) 2. Calcium ions leave muscle fiber thru T-tubules 3. ACTIN and MYOSIN slide apart VII. Skeletal Muscle Contraction *Letters Origin A. Actin & Myosin create Striation Patterns 1. Sarcomere = area from Z line to Z line 2. I bands – light bands composed of actin attached to Z lines 3. A bands – dark bands w/ myosin in middle, actin on edges Pg. 191 a) H zone of only myosin w/ an M line holding myosin in place 2. Fast Fibers forceful exercise (weight lifting) causes muscles to contract more new actin and myosin develop, increasing the diameter of muscle fiber 8 - 25 muscle enlarges (no new fiber made) Contraction - the pulling of a muscle against its attachments 1. 2. 3. 4. 8 - 20 8 - 21 Pg. 195 VIII. Fatigue A. During rest or moderate activity, enough O2 is present in muscle cells to do aerobic respiration B. Oxygen debt develops during strenuous exercise - Muscles lose their ability to contract & become fatigued C. Lactic acid (feeling of pain or of muscles burning) builds up as an end product of anaerobic respiration 1. A muscle cramp can occur due to a lack of ATP required to get rid of calcium ions so muscle fibers can relax 8 - 22 IX. Muscle Conditions A. Muscle Tone - achieved by sustained contraction within muscles, & is needed for normal posture 1. Slow Fibers – fatigue-resistant muscle fibers use (distance running, swimming) develop more mitochondria B. D. E. 8 - 23 B. Muscle Use & Disuse 1. Muscular Atrophy Decrease in size & strength of muscles due to disuse (accidents, space travel) less mitochondria, actin, & myosin 2. Muscular Hypertrophy – enlarged muscles due 8 - 26 to increased overuse ATP is needed from mitochondria The neurotransmitter, acetylcholine, is released at the neuromuscular junction Calcium (Ca) ions are released into muscle fibers thru T tubules ACTIN and MYOSIN slide together Sarcomere animation “Repaying” oxygen debt may take several hours Factors that may lead to muscle fatigue: - Accumulation of lactic acid - Loss/decrease in blood supply (less O2) - Loss of acetylcholine supply - Malnutrition (lack of glucose) - Respiratory problems (less O2) 8 - 24 C. Muscle Injuries 1. Mild Strain – few fibers injured, fascia intact, little loss of function 2. Severe Strain – many fibers & fascia torn, loss of function, pain, discoloration, swelling of tissues 3. Tetanic Contraction – sustained, forceful contraction that lacks relaxation (i.e. tetanus bacteria, drugs) 8 - 27 3 D. Rigor Mortis – muscle contraction at time of death muscles run out of ATP & Ca can’t be removed constant state of contraction after 72 hrs Actin and Myosin remain linked until muscle cells decompose 8 - 28 4