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What You Need for Your First Visit THE ADRENAL CENTER CARE TEAM After you have made an appointment, please have the following items delivered to our office at least one week prior to your visit, so that we may begin to organize a tailored care plan for you. William B. Inabnet, MD Alice C. Levine, MD Co-Director Co-Director PRIMARY SERVICES THE MOUNT SINAI MEDICAL CENTER ADRENAL CENTER Imaging Studies (Reports and Films) Your Medical Records Relevant blood work pertaining to your adrenal gland List of current medications and allergies to medications Any other pertinent information regarding your condition. Cardiology and Hypertension Lawrence Krakoff, MD Endocrinology Alice C. Levine, MD Endocrine Surgery William B. Inabnet, MD Kaare J. Weber, MD ASSOCIATED SERVICES AND PROVIDERS Cardiology and Vascular Disease Jeffery W. Olin, MD Adrenal Selective Venous Sampling Ageliki Vouyouka, MD Joshua L. Weintraub, MD Visiting Our Office The Mount Sinai Adrenal Center is located at 17 East 102nd Street on the 5th Floor. Should you have any questions or concerns, please feel free to contact us at (212) 824-2350 . A COMPREHENSIVE APPROACH TO CARING FOR DISORDERS OF THE ADRENAL GLAND By Subway: Take the 6 train to the 96th Street station or the 103rd Street Station. Walk East toward 5th Ave. By Bus: The M1, M2, M3, M96 and M 106 stop nearby our office. Neurosurgery and Pituitary-Based Disease Eliza Geer, MD Kalmon D. Post, MD, Anesthesia Andrew B. Leibowitz, MD Ian H. Sampson, MD 17 EAST 102ND STREET, 5TH FLOOR NEW YORK, NY 10029 Adrenal Pathology Pam Unger, MD Radiology and Nuclear Medicine Lale Kostakoglu, MD Eric J. Wilck, MD PRACTICE TELEPHONE: (212) 824-2350 (212) 202-4713 PRACTICE FAX: The Adrenal Center Mount Sinai School of Medicine 17 East 102nd Street, 5th Floor New York, NY 10029 A BOUT THE A DRENAL C ENTER A T THE MOUNT S INAI MEDICAL CENTER Mount Sinai Medical Center has a rich history of caring for patients with adrenal disorders. Because of their complex nature, adrenal disorders require a host of disciplines to maximize the care of the patient. The Adrenal Center at Mount Sinai brings all of these experts together as one multidisciplinary team to focus on all aspects of care for patients with adrenal disorders. We provide a team approach including Endocrinologists, Endocrine Surgeons, Cardiologists, Radiologists, Interventional Radiologists, Neurosurgeons, Nuclear Medicine Physicians, Anesthesiologists and Geneticists to provide comprehensive evaluation and treatment for these complex diseases. Our surgeons offer innovative minimally invasive approaches to adrenal surgery including both laparoscopic transabdominal and retroperitoneal approaches to adrenalectomy, single incision laparoscopic adrenalectomy, adrenal sparing surgery, and adrenal autotransplantation. All of these procedures are performed in our state of the art minimally invasive operating suites at the Mount Sinai Hospital affording patients improved cosmetic results, shorter hospitalization and quicker recovery. A DRENAL G LANDS There are two adrenal glands, each sitting on top of the kidneys. They produce a host of hormones, including cortisol, aldosterone, and the sex steroids estrogen and testosterone. Cortisol helps the body to respond to stress while aldosterone controls the balance of electrolytes including sodium and potassium in the body. The adrenal glands also produce catecholamines called epinephrine and norepinephrine. Together these hormones contribute to the “flight or fight” response to rigorous activity and stress. These glands are redundant organs such that the removal of one gland does not interfere with normal production and function of hormones from the remaining gland. D ISORDERS OF THE A DRENAL G LAND Disorders of the adrenal gland are often the result of over production of the various hormones described above. Medications can sometimes control the excess hormone release, but most often surgery is the only cure. PHEOCHROMOCYTOMA These tumors produce too much catecholamines (epinephrine and norepinephrine )resulting in dangerously high blood pressure which can often lead to stroke, heart attacks, and even death if left untreated. Removal of these tumors can be life saving and prevent devastating complications. Diagnosis can be challenging but patients often present with flushing, palpitations, and high blood pressure. These tumors can have malignant potential and patients require life long monitoring once diagnosed and treated. ALDOSTERONOMA These tumors produce too much aldosterone, often resulting in high blood pressure. Patients are usually on several medications with increasing doses to control their blood pressure. Patients are frequently found to have low potassium because aldosterone directly effects our salt and water balance. As a result, patients can complain of muscle cramps and weakness. These tumors are benign and their removal can result in a significant improvement in blood pressure control . These tumors can be small and often adrenal venous sampling is required to help determine the side of the aldosteronoma. CUSHING’S DISEASE AND SYNDROME Cushing’s syndrome is an over production of cortisol, the body’s primary intrinsic steroid. This can result in a host of problems. Prolong exposure to cortisol can result in weight gain, acne, thinning hair, and easy bruising. Patients can even suffer from diabetes, brittle bones, and an increased susceptibility to infection. Over production of cortisol can be associated with both benign and malignant conditions of the adrenal gland. ADRENAL INCIDENTALOMA Patients are often found to have incidental growths on their adrenal glands from imaging studies done for other reasons. These incidental growths are most often found on CT and MRI. The majority of these growths have no clinical significance and are truly incidental. However, it is important that both overproduction of hormones and the possibility of malignancy are excluded. Surgery is only performed if they are found to be producing excess hormone or if they reach a certain size, often 4cm or greater. ADRENAL CANCER Cancer of the adrenal gland is uncommon. They can produce a variety of hormones and often result in the rapid onset of symptoms. Surgery is often the only option for treatment and possible cure. These tumors can be large at the time of diagnosis and require open surgery for removal. SURGERY Most adrenal tumors can be removed using minimally invasive techniques. We offer a wide variety of approaches which are tailored to the individual needs of the patient in order maximize patient outcomes. These techniques include: Laparoscopic transabdominal approach where small incisions are made in the abdomen to access the adrenal glands. Laparoscopic retroperitoneal approach where small incisions are made on the back to gain access to the adrenals Single incision laparoscopic surgery (SILS) where a single incision is made at the belly button to perform the surgery The hormones produced by the adrenal gland are essential to normal function, but because the adrenal glands are redundant organs, patients can function with one gland. However, some conditions may require removal of both glands. We offer adrenal sparing surgery to patients who require removal of both glands. For patients who do not meet criteria for adrenal sparing surgery, we offer adrenal autotransplantation in the hopes of avoiding life long medication.