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THE CIRCULATORY SYSTEMS: The Cardiovascular and Lymphatic Systems Overview of the Circulatory System Cardiovascular Lymphatic System System The Medium The Conduit The Pump The Pathway Cardiovascular System: The Medium Cardiovascular Lymphatic System System The Medium The Conduit The Pump The Pathway Blood Blood: The “river of life” The only fluid tissue of the body Blood Composition Blood Composition • 45% blood cells –Erythrocytes (RBC), which transport oxygen –Leukocytes (WBC), which protect the body against pathogens –Platelets, cell fragments that aid in blood clotting Blood Composition • 55% plasma –Straw-colored liquid that consists of 90% water and dissolved substances (nutrients, salts, oxygen, carbon dioxide, hormones, plasma proteins, and wastes) Is Blood Blue? The color of blood depends on the amount of oxygen it is carrying –Bright red (oxygen-rich blood) –Dark red (oxygen-poor blood) Cardiovascular System: The Conduit Cardiovascular Lymphatic System System The Medium The Conduit The Pump The Pathway Blood Arteries and Veins The Conduit • Arteries, arterioles, and capillary beds carry O2 rich blood away from the heart • Venules and veins carry O2 poor blood to the heart Exceptions • Pulmonary (lung) veins carry O2 rich blood from the lungs to the heart. • Pulmonary arteries carry O2 poor blood from the heart to the lungs. Arteries vs. Veins The Similarities • Both carry blood • Both have three tunics (3-layered) –Tunica interna (inner layer) –Tunica media (middle layer of smooth muscle) –Tunica externa (outer layer) The Differences: Arteries • Arteries have thicker walls in order to withstand the higher pressure due to increased blood flow from the heart The Differences: Arteries • Most arteries carry O2 rich blood from the heart • Capillary beds are one cell layer thick and provide nourishment to cells and carry waste away from cells The Differences: Veins • Veins have thinner walls • Veins have larger openings (lumen) • Large veins have valves to prevent the backflow of blood The Differences: Veins • Action of lungs and muscles aid in venous return • Most veins carry O2 poor blood back to the heart Cardiovascular System: The Pump Cardiovascular Lymphatic System System The Medium Blood The Conduit Arteries and Veins The Pump The Heart The Pathway The Heart • Located in the bony thorax (rib cage) • Flanked by lungs on both sides • Muscular pump with four chambers –Two atrium –Two ventricles Circulation of Blood Through the Heart Cardiovascular System: The Pathway The Medium The Conduit The Pump The Pathway Cardiovascular System Blood Arteries and Veins The Heart Systemic and Pulmonary Circulation Lymphatic System The Lymphatic System The Medium The Conduit The Pump The Pathway Cardiovascular Lymphatic System System Blood Arteries and Veins The Heart Systemic and Pulmonary Circulation The Lymphatic System: The Medium The Medium The Conduit The Pump The Pathway Cardiovascular Lymphatic System System Blood Lymph Arteries and Veins The Heart Systemic and Pulmonary Circulation Lymph • Means “clear water” • Consists of fluids leaked from blood vessels that remain in tissue spaces • Primarily water with a small amount of dissolved proteins Lymphatic System: The Conduit The Medium The Conduit The Pump The Pathway Cardiovascular Lymphatic System System Blood Lymph Arteries and Lymphatic Veins vessels The Heart Systemic and Pulmonary Circulation Lymphatic Vessels • Pick up excess tissue fluid and return it to the bloodstream • One-way system (lymph only flows toward the heart) • Vessels become successively larger until it is returned to the venous system • Like veins, lymphatic vessels –Have thin walls –Are large vessels with valves –Have lower pressure than arteries –Move lymph along by the action of lungs and muscles Lymphatic Capillaries • Lymphatic capillaries drain tissues of fluid then deposit the fluid into lymphatic vessels. • Tissue fluid flows into the lymphatic vessel when the fluid pressure increases in tissues. Inflow from Tissue Fluid Endothelial cells overlap to allow fluid in, not out. Lymphatic System: The Pump The Medium The Conduit The Pump The Pathway Cardiovascular Lymphatic System System Blood Lymph Arteries and Lymphatic Veins Vessels The Heart No Pump Systemic and Pulmonary Circulation No pump System • The lymphatic system has no pump. • Lymph moves along by the action of lungs and muscles Lymphatic System: The Pathway Cardiovascular System Lymphatic System The Medium Blood Lymph The Conduit Arteries and Veins Lymphatic Vessels The Heart No Pump Systemic and Pulmonary Circulation Right Lymphatic Duct and Thoracic Duct The Pump The Pathway Lymphatic System: The Pathway • The lymphatic vessels on the right side of the body drains into the right lymphatic duct then into the right subclavian vein • The rest of the lymphatic vessels drain into the thoracic duct then into the left subclavian vein Lymphatic Nodes • Lymph nodes protect the body by removing foreign materials, such as bacteria and tumor cells • Produce lymphocytes that function in the pathogen-fighting response • Vary in shape and size Lymphatic Organs • Lymphatic organs protect the body against pathogens –Spleen (filters and cleanses the blood of bacteria, viruses, and other debris) –Thymus –Tonsils –Peyer’s patches