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The Major STDs A. Sexually transmitted diseases(STD)--also called sexually transmitted infections (STI)--are spread from person to person mainly through sexual activity. 1. These diseases are considered major threats because they are serious in themselves, can cause serious complications if left untreated, and pose risks to a fetus. a. HIV/AIDS b. Hepatitis c. Syphilis d. Chlamydia e. Gonorrhea f. Herpes g. Human papollomavirus (HPV) 2. STIs are caused by viruses, bacteria, fungi, and protozoa. 3. Human immunodeficiency virus (HIV) causes acquired immunodeficiency syndrome (AIDS). a. AIDS originated in Africa during the early twentieth century but was not recognized until 1981. b. It is estimated that 65 million people have been infected, or almost 1 percent of the world’s population. Currently about 33 million people are infected with HIV/AIDS. c. The epidemic appears to be slowing, however, AIDS remains the leading cause of death in Africa. d. In the U.S. about 1.1 milliong people have been infected with HIV and 500,000 have died. About 21 percent of Americans infected with HIV are unaware of their condition. 4. In 1998 researchers discovered a similar virus in wild chimpanzees called simian immunodeficiency virus (SIV). a. Genetic evidence shows that SIV infected humans in the 1930’s from trapping and butchering of chimpanzees was common. 5. HIV attacks the immune system, which normally would destroy any virus that enters the body. a. HIV takes over CD4 T cells, monocytes, and macrophages, which are essential elements of the immune system. b. HIV enters a human cell and inserts its own genetic material into the host cell. c. The viral DNA forces the CD4 cell to make new copies of HIV. The CD4 cell becomes incapable of performing its immune functions. d. The immune system cannot keep pace with the rapid replication of the virus. e. 6. 7. 8. The destruction of the immune system is signaled by the loss of CD4 T cells; as the number declines, an infected person may experience symptoms. f. A person has full-blown AIDS if a condition defined as a marker for AIDS is present or if CD4 cell level drops below a certain level. The infections that prove deadly for those with HIV are seldom serious for people with a healthy immune system. Opportunistic infections usually are caused by organisms that are very common in the environment. During the first weeks after infection with HIV, called the primary infection phase, about 50 percent of people develop flu-like symptoms. During this phase people have large amounts of HIV in the bloodstream, making them much more infectious than they will be several months later when they enter the chronic stage. a. Experts believe that about half of all cases of HIV infection are acquired from people who are in the primary infection stage. (1) Most people in this stage have no idea they are infected. (2) Even if they suspect that they may be infected and get tested, the most commonly used tests for HIV will be negative in this stage. (3) Special tests can detect primary HIV infection. Increasing awareness of primary infection could help reduce the spread of the virus. b. During the next phase, called the chronic asymptomatic or the symptom-free stage, most people feel well. This period can last 2 to 20 years. The virus is progressively infecting and destroying the cells of the immune system. c. People with HIV can transmit the infection to others when they are symptom-free. Even if they receive treatment, they remain infectious to a varying degree throughout their lives. HIV is transmitted by blood and blood products, semen, vaginal and cervical secretions, and breast milk. a. The three main routes of transmission are: (1) From specific kinds of sexual contact (2) From direct exposure to infected blood (3) From an HIV-infected mother to her fetus during pregnancy or childbirth, or to an infant during breastfeeding. b. The most likely method of HIV transmission is unprotected anal or vaginal intercourse. Unprotected anal intercourse is the riskiest of sexual activities. (1) The risk of HIV transmission during oral sex increases if a person has poor hygiene or oral sores, or has brushed or c. d. e. f. g. h. flossed just before or after oral sex. Some evidence suggests that recent consumption of alcohol may make the cells that line the mouth more susceptible to infection with HIV. (2) HIV can be transmitted through tiny tears, traumatized points, or irritated areas in lining of the vagina, cervix, penis, anus, and mouth and through direct infection of cells. (3) The presence of lesions, blisters, or inflammation from other STDs makes transmission more likely. (4) Any irritation of tissues that might result from rough or unwanted intercourse and the use of enemas before anal intercourse increase the risk of transmission. (5) Spermicides also may cause irritation and increase the risk of transmission. HIV is more likely to be transmitted through sexual assult because protection is rarely used and the tissue trauma is generally greated than with unforced sexual activity. Direct bloodstream contact can result from the sharing of needles used for injecting drugs. HIV also can be transmitted through needles used for acupuncture, tattooing, and piercing parts of the body. (1) HIV infection was transmitted through the blood supply before screening became available. The current risk of transfusionrelated HIV transmission is less than 1 in 2 million (per unit of blood product) in the United States. The WHO estimates that about 5 percent of all cases of HIV infection worldwide have resulted from the transfusion of infected blood and blood products. (2) Health-care workers can be infected from inadvertent needle sticks when caring for an HIV-positive patient. About 25 percent to 30 percent of infants born to untreated HIVpositive mothers are infected. (1) HIV-infected children rarely appear ill at birth, but they begin to develop health problems over the first months and years of life. (2) About 20 percent of infected children become very ill and progress to AIDS or death by age 4; the remaining 80 percent develop problems more slowly. Although trace amounts of HIV have been found in saliva and tears, it probably cannot be transmitted through those fluids. It may possibly be transmitted through urine and feces. HIV is not transmitted by casual contact. In the United States, the most common means of transmission has been sexual activity between men, followed by injection drug use and heterosexual contact. (1) 9. The CDC estimated that in 2008 75 percent of HIV-positive Americans were men and the remaining 25 percent were female. i. Disproportionately high rates of infection in certain groups are tied to social, cultural, and economic factors. HIV is increasingly affecting minorities, women, and the poor. (1) Heterosexual transmission accounts for a growing proportion of new cases, while the share caused by sex between men and injection drug use is falling. (2) Women, especially African American women and Latinas, make up an increasingly large proportion of all U.S.’ AIDS cases. (3) African American men and women are vastly overrepresented among people newly diagnosed with AIDS. (4) AIDS incidence and deaths have declined since 1996 among all groups of Americans, but these declines have been smaller among women and minorities compared with other groups. (5) Young men who have sex with men are at increased risk for HIV infection because more young men are engaging in unsafe sexual practices such as unprotected anal intercourse. This trend may be caused by younger gay men being less likely than older gay men to have had the experience of watching friends die from AIDS and also may be less afraid of acquiring the disease because of advancing treatment and a false belief that a cure is near. (6) There are also a growing number of cases among men who acquire HIV through sex with older men but who do not identify themselves as gay. Particularly among minorities, many men who have sex with men also have sex with women, and they identify themselves as heterosexual, not gay or bisexual. (7) Reducing rates of transmission will require dealing with problems of drug abuse, poverty, and discrimination. (8) Increased testing is one of the most important aspects of HIV prevention, but knowledge of HIV status may not be enough to change behavior. Studies show that about one-third of people who have been diagnosed with HIV continue to have unprotected sex. About half of the people infected with HIV will develop symptoms soon after exposure. Symptoms may include fever, fatigue, rashes, headaches, swollen lymph nodes, body aches, night sweats, sore throat, nausea, and diarrhea. a. Pneumocystitis carinii pneumonia is the most common infection seen in people with HIV. Kaposi’s sarcoma, a rare form of cancer, is commonly seen among infected men. c. Infected women often have persistent vaginal yeast infections. Because drugs can slow the progress of HIV infection, early diagnosis is important. a. The most common tests for HIV check for the presence of antibodies to the virus. (1) HIV primarily disrupts T-cell immunity, but B cells are still able to produce antibodies to HIV and will show up in tests. (2) Unfortunately, these antibodies do not protect against the spread of the virus. The presence of an antibody indicates an active case of the disease. b. The HIV antibody tests are used for screening because they are accurate and inexpensive. (1) Standard testing involves an initial test, called ELISA. If this test is positive, a second test called a Western Blot, or immunoflourescence assay, is performed to confirm the results. (2) However, not everyone with HIV will test positive on antibody tests. Antibodies may not appear in the blood for weeks or months after infection, so newly infected people are likely to have a negative test result. (3) A more expensive test, the HIV RNA test, directly measures the presence of the virus. (4) Rapid (same-day) HIV tests are effective. (5) Babies born to HIV-infected mothers may carry HIV antibodies passed from their mother and test positive on an HIV antibody test without being infected with HIV. Further tests must be performed to determine whether the infant is infected. c. If an individual is HIV-positive, one gauges the status of the immune system by measuring CD4 T-cell levels. d. One monitors the progress of the infection by measuring the amount of the virus in the body. A diagnosis of AIDS is made if an HIV-positive person either has an infection defined as an AIDS indicator or has a severely damaged immune system as measured by CD4 T-cell counts. Among those who have never been tested, nearly 75 percent say that they haven’t been tested because they don’t think they are at risk. About 10 percent say they are afraid to have blood drawn, 6 percent say they are worried about confidentiality, and another 6 percent say they don’t know where to go to be tested. b. 10. 11. 12. a. 13. 14. Many people are not aware that rapid HIV tests, home tests, and tests that do not require a blood sample are now available. b. A new diagnostic test, HIV Replication Capacity, shows how fast HIV from a patient’s blood sample can reproduce itself. It is a measure of viral “fitness,” and may be helpful when used in conjunction with CD4 and viral load tests in predicting how quickly a given person may progress to more serious disease. c. The CDC recommends that men who have sex with men should be tested at least once a year, and people who engage in high-risk behavior should be tested more often. All cases in the U.S. of diagnosed HIV or AIDS must be reported to public health authorities. a. Tracking has been difficult. (1) Prior to 2006 California had not been included in the national data because of its method of collecting data. (2) A standard positive HIV test only shows the presence of infection, not nessessarily a new case. (3) A new blood test makes it possible to estimate the length of time a person has been infected, allowing a more accurate picture. HIV infection has no known cure, but new drugs can alter the course of the disease and extend life. The drop in the number of U.S. AIDS deaths since 1996 is largely due to treatment with combinations of new drugs. a. Research focuses on several types of antiviral drugs and on drugs that stimulate or regulate the immune system. (1) Reverse transcriptase inhibitors, including the widely used AZT (zidovudine), inhibit the integration of HIV genetic material into human cells. (2) Protease inhibitors target the enzyme HIV uses to create a protein coat for each viral copy. (3) Entry inhibitors block HIV from entering and infecting cells (4) Treatment with combinations of drugs, called highly active antiretroviral therapy (HAART), can reduce HIV in the blood to undetectable levels, although HIV-infected men on HAART may still transmit HIV to others through body fluids. (5) Other antiviral drugs are under development. (6) HIV/AIDS treatment is becoming increasingly complex—not only because the virus can mutate and behave unpredictably, but because so many treatment options are available. b. There are several potential postexposure (PEP) treatments for HIV. Antiviral medications are being used in some cases to prevent 15. 16. 17. 18. infection in people who have been exposed to the virus. PEP involves 28 days of HAART which should begin within 72 hours of exposure. c. Antibiotics are used to prevent opportunistic infections. The risk of transmitting HIV from an infected mother to her baby can be reduced by 2 percent by treating the mother during her pregnancy and labor, giving the baby antiretroviral drugs during the fist weeks of life, avoiding breastfeeding, and delivering the baby by cesarean section if necessary. a. Without treatment, 25 percent-30 percent of infants born to HIVinfected women are themselves infected with the virus. b. A cesarean delivery can reduce the risk of infection in women who have high blood levels of HIV. Women who have undergone antiviral treatment and have very low levels of HIV usually can deliver vaginally. There are major challenges in the treatment of HIV. a. The cost of drugs is prohibitive for many, particularly in developing countries. b. A 2006 study estimated the average cost of treatment in the U.S. at $2,100 per month. c. Antiretroviral drugs can have serious side effects, short term include; nausea, vomiting, diarrhea and fatigue. Long term effects include; abnormal blood lipids, heart disease, liver problems, bone loss, kidney disease and cancers. d. The regimen for taking drugs is complicated, and failing to follow it precisely can lessen their effectiveness and may allow the virus to develop resistance. e. Some people cannot tolerate the side effects, and the drugs may not be as effective for some people as for others. Development of an effective, safe, affordable vaccine is the best hope for stopping the spread of HIV. Experts are discouraged by recent vaccine trial failures stating that a licensed AIDS vaccine is now estimated to be at least a decade away. a. Researchers are making faster progress in developing a microbicide, a kind of chemical condom that could prevent the spread of AIDS. b. Another approach is the use of pre-exposure treatment as prevention. Although controversial, HIV-negative individuals at high risk for infection would take an anti-HIV medication before an activity that might expose them to HIV. c. The female condom may someday play a larger role in HIV prevention. HIV infection is a preventable disease. a. B. Anyone not involved in a long-term mutually monogamous relationship should abstain from any sexual activity that involves the exchange of body fluids. b. Use of a lubricated condom reduces the risk of transmitting HIV during all forms of intercourse. c. Limiting the number of partners and communicating openly with partners helps reduce risk. Recent surveys of HIV-positive people found that one-third failed to reveal their HIV status to sexual partners; of these, nearly two-thirds failed to always use a condom. d. Most college students do not follow safer sex practices and therefore are at high risk for contracting HIV. e. Injection drug users should not share needles and should obtain help in breaking their drug habit. f. The cornerstone of prevention is education. Chlamydia trachomatis causes chlamydia, the most common bacterial STD in the United States, with about 1 million new cases in 2006. 1. The highest rates of infection are in single people etween the ages of 15 and 24, however, women face the greatest consequences from chlamydia infection. a. In women, chlamydia produces no early symptoms but can lead to extensive damage, including pelvic inflammatory disease (inflammation of the fallopian tubes) and ectopic pregnancy. b. African-American women have seven times the rate of white women for chlamydia. c. Men with chlamydia risk urinary tract infections and epididymitis (inflammation of the testicles). d. Infants can contract chlamydia during passage through the birth canal during delivery, leading to eye infections and pneumonia. More than 150,000 babies are born each year with infections as a result of untreated maternal chlamydia. 2. Symptoms in men include painful urination and watery discharge from the penis; women may experience vaginal discharge, painful urination, and painful inflammation of the oviducts, which is symptomatic of PID. Most people have few or no symptoms, making inadvertent spread of the disease more likely. 3. Chlamydia is diagnosed through laboratory tests. Specimens usually are obtained by collecting a urine sample or a small amount of fluid from the urethra or cervix and then by growing the organism in culture. 4. Treatment for chlamydia includes antibiotics. 5. Treatment of both partners is important to avoid reinfection. C. D. Gonorrhea is caused by the bacteria Neisseria gonorrhoeae, which flourishes in mucous membranes. It cannot live long outside the human body, dying within moments of exposure to light and air. 1. In 2006, more than 350,000 cases of gonorrhea were reported to the CDC, a 5.5 percent increase over 2005. a. Gonorrhea is underreported because it is often symptomless. 2. Like chlamydia, if untreated, gonorrhea can cause PID in women and epididymitis and urethritis in men. a. It also can cause arthritis, rashes, and eye infections, and it occasionally involves internal organs. b. Being infected with gonorrhea increases the likelihood that HIV will be transmitted. c. In addition, infants can contract gonococcal conjunctivitis, leading to blindness, while passing through the birth canal of an infected mother. Antimicrobial eye drops, given at birth, prevent the infection. 3. Symptoms of gonorrhea in men include urethritis, which makes urination painful; thick yellow-white discharge from the penis; inflammation at the urethral opening; and enlarged lymph nodes. Up to half will have very minor symptoms or no symptoms at all. 4. Most women with gonorrhea exhibit no symptoms and do not realize they are infected. Those who do have symptoms may experience mild vaginal discharge, painful urination, and severe menstrual cramps. 5. Gonorrhea bacteria also can infect the throat or rectum, leading to sore throat or pus on the tonsils, pus in the feces, or rectal irritation, pain, and itching. 6. Gonorrhea is diagnosed by evaluating samples of body fluids. a. New antibiotics are necessary because gonorrhea has developed drug resistance. b. Additional antibiotics may be needed to treat people who also have chlamydia. 7. After treatment, one can become reinfected by having sexual contact with an infected partner. Pelvic inflammatory disease (PID) is a major complication in 10 percent to 40 percent of women who have been infected with gonorrhea or chlamydia and have not received treatment. 1. PID occurs when the initial untreated infection travels beyond the cervix. 2. About one-fourth of women who are successfully treated for PID are susceptible to recurrent infection, ectopic pregnancy, sterility, and chronic pelvic pain. 3. PID is the leading cause of infertility in young women. 4. E. The more sex partners a woman has, the greater her risk of PID. Other risk factors include smoking, IUD use, and vaginal douching. 5. Women with PID often are asymptomatic. Some may experience chills, fever, nausea, vomiting, abdominal pain, abnormal vaginal bleeding, prolonged menstruation, or abnormal vaginal discharge. 6. PID is diagnosed on the basis of symptoms, examination, ultrasound, and testing; laparoscopy may be used to isolate the suspected organism and culture it. 7. Treatment includes immediate antibiotics, possibly with hospitalization for intravenous administration. 8. If a woman has PID, it is important for her partners to be treated, even if asymptomatic. Human papillomavirus (HPV) infection (genital warts) has increased in recent years and is the most common STD in the United States. 1. Human papillomavirus (HPV), the causative agent, causes many types of warts. There are about 100 different strains of HPV. More than 30 types are likely to cause genital infections, and five are implicated in cervical cancer. Other strains are linked to anal, penile, and other genital cancers. 2. The precancerous condition known as cervical dysplasia often occurs among women with untreated genital warts. 3. Genital wart infections are very contagious through contact with lesions. Condoms do not provide complete protection. 4. Many people who carry HPV have no visible symptoms; asymptomatic people can infect others. Even after treatment, HPV can continue to infect neighboring tissue. In addition, babies can be infected during delivery. 5. Warts may appear as small bumps or as large warty growths. If untreated, they can grow into cauliflower-like masses that may obstruct the urethra, leading to irritation and bleeding, painful urination, and urethral discharge. HPV-infected tissue often appears normal. 6. Warts may appear on the vulva, labia, perineum, and cervix—making them difficult to see. 7. The incubation period for genital warts ranges from 1 month to 2 years. 8. Genital warts are diagnosed by the physical appearance of the lesion or by discovery of HPV infection of the cervix by Pap test. New tests are available to detect the presence of HPV infection and to distinguish among the more common strains of HPV, including those that cause most cases of cervical cancer. 9. Treatment focuses on reducing the number and size of the warts, although most warts eventually disappear, even without treatment. Many current treatments are painful and physically destructive, and none can ensure eradication of HPV b. F. Warts also can be removed by electrocautery, cryosurgery, or laser therapy. c. Currently available treatments do not eradicate HPV. 10. Because treatment eradicates an individual wart but not the virus in a person’s system, an infected person still can infect others. 11. Warts may persist and become severe in people with an impaired immune system. 12. The FDA has approved the vaccine, Gardasil, as a vaccine for HPV. The vaccine is recommended for females aged 11-12, ideally before their first sexual activity. 13. Regular screening is suggested for all women. Genital herpes affects about one in five adults in the United States. It plays a major factor in the transmission of HIV worldwide. Most people infected with HIV also are infected with HSV 2, and herpes lesions contain large amounts of HIV, making it more likely that the virus is transmitted. The presence of herpes lesions in an HIV-negative person increases the likelihood that he or she will be infected by an HIV-positive partner. 1. Two different viruses in the herpes family can cause genital or oral-labial lesions. a. HSV 1 causes cold sores and fever blisters around the mouth. It is extremely common in the United States. b. Genital herpes due to HSV 1 usually is acquired through oral-genital contact. c. HSV 2 (genital herpes) usually causes sores in the genitals and is almost always sexually transmitted. 2. The risk of mother-to-child HSV transmission during pregnancy and delivery is less than 1 percent in women with longstanding herpes infection. 3. Herpes is incurable. After the initial infection, the victim is subject to unpredictable outbreaks. Each time the disease recurs, the victim is contagious again. 4. Symptoms occur 2 to 20 days after exposure, although up to 90 percent of infected people have no symptoms. a. Symptoms include painful, fluid-filled lesions and flulike sensations. b. After the herpes virus has produced an initial outbreak, it lies dormant and can recur at any time. Outbreaks can be triggered by stress, exposure to sunshine, acute illness, generally poor health, or other factors. 5. Herpes is diagnosed by the presence of lesions and systemic symptoms. A culture can be performed. Several blood tests can detect the presence of HSV antibodies. Older tests did not distinguish between HSV 1 and HSV 2, while newer tests can. a. G. H. Studies show that adults infected with HSV 2 are 15 times more likely than those without HSV 2 to be infected with HIV. 6. Acyclovir or other suppressive treatment significantly reduces the number of painful outbreaks and reduces viral shedding between outbreaks. 7. An herpes vaccine is undergoing testing but has not had positive results. Hepatitis (inflammation of the liver) has many causes. It can be transmitted sexually as well as through nonsexual contact. 1. The hepatitis B virus (HBV) is found in all body fluids and is easily transmitted through any sexual activity that involves the exchange of body fluids, use of contaminated needles, and blood-to-blood contact. a. It also can be transmitted through nonsexual close contact. b. Primary risk factors are sexual exposure and injection drug use. c. A pregnant woman can transmit the virus to her child, although HBV screening has greatly reduced the incidence. 2. Symptoms resemble those of the flu, but they are not always obvious. a. The incubation period is about 30 to 180 days. b. Nausea, vomiting, dark-colored urine, and jaundice are possible symptoms. c. People with hepatitis B may become chronic carriers. d. Acute hepatitis B can result in prolonged illness or even death. 3. Blood tests that analyze liver enzymes are used for diagnosis. 4. There is no cure for hepatitis B and no specific treatment for chronic infections. Antiviral drugs may be used for cases of chronic HBV infection. Treatment with hepatitis B immunoglobulin can protect people exposed to HBV. 5. Preventive measures for hepatitis B are similar to those for prevention of HIV. a. The vaccine for hepatitis B is safe and effective. b. The vaccine is recommended for everyone under age 19 and for all adults at increased risk for hepatitis B, including people with more than one sex partner is 6 months, men who have sex with other men, those who inject illegal drugs, and health care workers who are exposed to blood and body fluids. The prevalence of syphilis, once widespread, has declined dramatically. About 7,000-10,000 new cases of early syphilis are diagnosed each year. 1. The open sores associated with syphilis dramatically increase the risk of contracting HIV or transmitting it to someone else. 2. Syphilis can be effectively treated with antibiotics. 3. Syphilis is caused by the spirochete Treponema pallidum. a. 4. 5. 6. VI. A. It is transmitted through sexual contact or to a fetus through the placenta of an infected mother. b. The organism passes through any break or opening in the skin; therefore it can be transmitted by kissing, vaginal or anal intercourse, or oral-genital contact. Syphilis has three stages. a. Primary syphilis is manifested by a single chancre, or sore, smaller than a dime, that appears at the site where the organism entered the body within 10 to 90 days after contact. (1) Chancres contain large numbers of bacteria, making the disease highly contagious when they are present. (2) Chancres also can occur in the mouth and on the breasts or fingers. b. Secondary syphilis is characterized by flulike symptoms and a skin rash that appears about 3 to 6 weeks after the chancre developed. (1) The rash may cover the entire body or a few areas, but the palms of the hands and soles of the feet usually are affected. (2) If the disease remains untreated, relapses can occur. c. Third stage (latent) syphilis exists by definition in those with evidence of having had syphilis. (1) The organism invades the internal organs, possibly causing dementia, cardiovascular damage, blindness, and death. (2) Infected pregnant women can transmit the organism across the placenta, leading to stillbirth, prematurity, or congenital deformity. Diagnosis is made from a specimen of infected tissue and through blood tests. Antibiotics are used for treatment of all stages, but damage from late syphilis can be permanent. Other STDs Trichamoniasis, or trich, is caused by a single celled organism, Trichomonas vaginalis, which thrives in warm, moist conditions, making women particulatly susceptible. 1. Symptoms include greenish, foul-smelling vaginal discharge and severe pain and itching in the vagina. 2. Early treatment is important because studies suggest trich may increase the risk of HIV transmission and premature delivery. 3. Treatment is with metronidazole (Flagyl), and both partners must be treated simultaneously. B. C. Bacterial vaginosis (BV) involves a shift in the makeup of bacteria that normally inhabit the vagina and is associated with sexual activity. 1. Symptoms of BV include a vaginal discharge with a fish-like odor and vaginal irritation. 2. Some studies show an association between BV and increased risk of PID, HIV transmission, infection after childbirth or gynecological surgery, and premature delivery in pregnant women. 3. BV is treated with topical and oral antibiotics but often reoccurs. Pubic lice (crabs) are not technically a disease but are an infestation that is highly contagious, both sexually and nonsexually. 1. Treatment is generally easy using over-the-counter or prescription shampoo and lotion, which is applied to the body, and all clothes and linens must be washed. VIII. What You Can Do A. Education is a cornerstone of STD prevention, greatly fueled of late because of the HIV epidemic. 1. Education programs have led to an increase in condom use, but lapses in safer sex practices, especially among younger gay men, are common. 2. Among certain groups, such as injection drug users, infection rates are still increasing. 3. Everyone is individually responsible for learning about and preventing STDs. B. Early diagnosis and treatment can help prevent further infection and spread. 1. Every young, sexually active person should be vaccinated for hepatitis B. a. Men who have sex with men should be vaccinated for hepatitis A. b. Girls and women aged 9-26 should be vaccinated for HPV. c. The CDC recommends that everyone between the ages of 13 and 64 be tested for HIV at least once during routine medical care. 2. Self-examination is an important part of diagnosis. 3. Almost all STDs can be asymptomatic, making periodic screening essential. 4. If you have had a risky sexual encounter, see a physician as soon as possible. 5. Testing can be performed at private physicians’ offices, public health clinics, community health agencies, and some student health services. 6. After diagnosis, treatment should begin immediately, and partners should be informed so they also can start treatment. No sexual activity should take place during treatment until further tests indicate a cure. 7. C. Ethical behavior requires informing all sex partners about the infection, even though it is difficult. 8. Treatment and cure of an STD does not guarantee a person will not get it again; once treated, people need to know how to avoid being infected again. Prevention is the best method of dealing with STDs. 1. Practicing abstinence is the only sure way to avoid exposure to STDs. Assuming responsibility for safer sex practices will greatly reduce or eliminate the risk of contracting an STD. 2. Communication between partners is an essential part of prevention. 3. Using alcohol and drugs leaves you vulnerable to sexual assault and increases the risk of acquiring a serious STD. 4. Practicing responsible sexual behavior means protecting yourself and others from STDs.