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DNA Review Packet #1-13 S Question 1 S Q1. What is DNA and why is it important to Forensic Science? S DNA is the molecule that carries the body’s genetic information. It is important to FS because portions of the DNA structure of certain genes are unique to each individual. This allows FS to link biological evidence to a single individual with certainty. Question 2 S Q2. What are genes and what is their function? Of what are genes composed of and where are they located? S Genes are the fundamental units of heredity. Their function is to instruct cells in the body to make proteins. Genes are composed of DNA and they are located on chromosomes within the nucleus. Question 3 S Q3. With what discovery are James Watson and Francis Crick credited? S A3. James Watson and Francis Crick are credited with discovering the structure of DNA. Question 4 S Q4. DNA is a large molecule created by linking a series of repeating units. What is this type of molecules called? What are the repeating units known as? S DNA is a large molecule called a polymer. DNA is composed of a series of repeating units called nucleotides. The monomers of DNA are nucleotides. Question 5 S Q5. Describe the basic structure of DNA. S The basic structure of the DNA molecule is that of a double helix or twisted ladder. Question 6 S Q6. Name the 4 bases associated with DNA. How are the bases paired on the DNA molecule? S The 4 bases are Adenine, thymine, cytosine and guanine. S A-T S G-C Q7. What aspects of DNA defines the role and function of a DNA molecule? S The order in which the base pairs are arranged defines the role and function of a DNA molecule. Q8. DNA controls inheritable traits by producing complex molecules called? S proteins Q9. How are proteins made? What determines the shape and function of a protein molecule? S Proteins are made by linking a combination of amino acids through the processes of transcription and translation. S The sequence of amino acids in a protein chain determines the shape and function of the protein. Q11. Briefly describe the process of DNA replication SDNA replication S Starts with the separation of DNA strands S Then enzymes use each strand as a template S To assemble new nucleotides into complementary strands S Many enzymes and proteins, such as DNA polymerases, are involved in unwinding the DNA, keeping the DNA strands apart, and assembling the new DNA strands. Q12. What is PCR? Why is it useful to forensic scientists? S Polymerase chain reaction (PCR) is a technique for replicating small quantities of DNA or broken pieces of DNA found at a crime scene, outside a living cell. S The ability to multiply small bits of DNA now means that sample size is no longer a limitation in characterizing DNA recovered at a crime scene. Q13. What are tandem repeats? How are they useful to forensic scientists? S Tandem repeats are regions of a chromosome that contain multiple copies of a core DNA sequence arranged in a repeating fashion. S They are useful to FS because they offer a means of distinguishing one individual from another through DNA typing.