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CARTILAGE. • Modified connective tissue, which forms the skelital basis of some parts of the body. • E.g. Auricle of the ear, lower part of the nose. CONNECTIVE TISSUE. • The tissue which fills the interstices between more specialized elements. • Serves to hold them together and support them. CONNECTIVE TISSUE. General connective tissue Special connective tissue Cartilage Bone Blood Adipose tissue Lymphyoid tissue Haemopoitic tissue Components • Cells Chondrocytes • FibresCollagen OR elastic fibres . • Ground substances Tissue fluids GAG and proteoglycans 4 Chondrocytes • Mesenchymal cell • Lie in spaces lacunae 5 COLLAGEN FIBRES OF CARTILAGE. • Type 2 collagen. • Fibrocartilage,perichon drium contain Type 1. Types A. Hyaline cartilage B. Elastic cartilage C. Fibrocartilage 7 Hyaline cartilage(hyalos=glass) Pearly white,glassy Homogeneous(same refractive index Perichodrium a. Fibrous layer(outer) b .cellular layer(inner 8 • Chondrocytes are present inside the cavities called, lacunae(tiny spaces in the matrix) • Each lacunae generally contain single cell. • Towards the centre, cells are arranged in groups called CELL NESTS(offspring of a common parent cell.) 9 Martix (fibres+ground substances) • Capsule or territorial matrix—newly formed matrix . • Interterritorial matrix-old matrix. 10 11 DISTRIBUTION • Costal cartilage • Articular cartilage • Thyroid, cricoid, arytenoid • Tracheal rings • Part of nasal septum • Epiphyseal plate 12 WHITE FIBRO CARTILAGE It is intermediate between Dense connective tissue and hyaline cartilage (tensile strength) Chondrocytes are found in singles or in rows with bundles of collagen with little matrix. No perichondrium. Bundles of collagen(type1) 13 14 Distrubution • Secondary cartilaginous jointsintervertebral discs,pubic symphysis. • Articular discs. • Glenoid labrum, acetabular labrum. • Near tendon insertion. 15 16 Elastic cartilage(yellow fibrocartilage) • Greater flexibility • The ground substance contains abundance of branching and anastomosing elastic fibres • No isogenous cell nests. • Chondrocytes are found in single or in small groups. 18 19 Distrubution • Auricle and lateral part of the external acoustic meatus. • Medial part of auditory tube. • Epiglottis ,corniculate,cuneiform,apical part of arytenoid. 20 21 MUSCLE TISSUE DEFINITION • It is one of the four basic tissue in the body • This tissue is specialized for contraction and conduction of impulse • All the muscle tissue consists of elongated cells called as muscle fibers/myocytes. • Each muscle cell has cytoplasm called as sarcoplasm & the surrounding cell membrane sarcolemma. • The muscle fiber contains numerous myofibrils in the sarcoplasm which inturn contains contractile protein actin & myosin. CLASSIFICATION. • Skeletal muscle. • Cardiac muscle. • Smooth muscle. CLASSIFICATION. • Striated muscle. • Non-striated muscle. CLASSIFICATION. • Voluntary muscle. • Involuntary muscle. SKELETAL MUSCLE • These muscles are attached to skeleton and hence they are called skeletal muscle • They can be contracted & relaxed at will, are called voluntary muscles. • Microsopic st. shows light &dark bands – striated. CONNECTIVE TISSUE COMPONENT • Epimysium • Perimysium • Endomysium FEATURES OF SKELETAL MUSCLE. • Striations. • Alternate dark and light bands. • Dark A-band. • Light I-band. FEATURES OF SKELETAL MUSCLE. FEATURES OF SKELETAL MUSCLE. CARDIAC MUSCLE • It is involuntary, cross striated muscle, present only in heart. • Cardiac muscle is similar to skeletal muscle in most of the structures, but developmentally, functionally and by its nerve supply it resembles the smooth muscle. • Muscle fibres show extensive branching and anastomosis with slit spaces between them. • Cells contain sarcoplasm, myofibrils like skeletal muscle, but contain only one nucleus in one cell. • Nucleus is oval and placed centrally. • Sarcoplasm is abundant but myofibrils are less in number. Distinguishing and characteristic feature of cardiac muscle fibres are the intercalated discs. SMOOTH MUSCLE • • • • • Non striated, involuntary. Made up of long spindle shaped cells. Broad central part and tapering ends. Nucleus is oval or elongated. Lies in the central part of the cell. • With light microscope the sarcoplasm appears to have indistinct longitudinal striations, but there are no transeverse striations. • Distribution – walls of hollow viscera. COMPARISION BETWEEN MUSCLES Skeletal muscle Cardiac muscle Smooth muscle Morphology Long & cylindrical fibers Short & cylindrical branching Spindle shaped fibers Striations Present, very prominent Present, less prominent No striations Nucleus Multiple, flattened, peripheral Single, oval, central Single, oval, central Intercalated disc Absent Present Absent