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Transcript 
Purification of Cardiomyocytes From Differentiating
Pluripotent Stem Cells Using Molecular Beacons That
Target Cardiomyocyte-Specific mRNAClinical Perspective
by Kiwon Ban, Brian Wile, Sangsung Kim, Hun-Jun Park, Jaemin Byun, Kyu-Won
Cho, Talib Saafir, Ming-Ke Song, Shan Ping Yu, Mary Wagner, Gang Bao, and
Young-Sup Yoon
Circulation
Volume 128(17):1897-1909
October 22, 2013
Copyright © American Heart Association, Inc. All rights reserved.
Structure of cardiomyocyte-specific molecular beacons (MBs).
Kiwon Ban et al. Circulation. 2013;128:1897-1909
Copyright © American Heart Association, Inc. All rights reserved.
Overall strategy to enrich human pluripotent stem cell–derived cardiomyocytes using molecular
beacons that target cardiomyocyte-specific mRNA.
Kiwon Ban et al. Circulation. 2013;128:1897-1909
Copyright © American Heart Association, Inc. All rights reserved.
Characterization of cardiomyocyte-specific molecular beacons (MBs).
Kiwon Ban et al. Circulation. 2013;128:1897-1909
Copyright © American Heart Association, Inc. All rights reserved.
Purification of cardiomyocytes from differentiating mouse embryonic stem cells (mESCs) with
cardiomyocyte-specific molecular beacons (MBs).
Kiwon Ban et al. Circulation. 2013;128:1897-1909
Copyright © American Heart Association, Inc. All rights reserved.
Purification of cardiomyocytes from differentiating human embryonic stem cells (hESCs) by cell
sorting via molecular beacon (MB) and fluorescence-activated cell sorting (FACS).
Kiwon Ban et al. Circulation. 2013;128:1897-1909
Copyright © American Heart Association, Inc. All rights reserved.
Purification of cardiomyocytes from differentiating human induced pluripotent stem cells
(hiPSCs) by cell sorting via molecular beacon (MB) and fluorescence-activated cell sorting
(FACS).
Kiwon Ban et al. Circulation. 2013;128:1897-1909
Copyright © American Heart Association, Inc. All rights reserved.
Transplantation of unpurified and purified cardiomyocytes into a mouse model of acute
myocardial infarction.
Kiwon Ban et al. Circulation. 2013;128:1897-1909
Copyright © American Heart Association, Inc. All rights reserved.
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