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Anatomy and Physiology Anatomy • Anatomy • The study of the structure or form of living things Physiology • Physiology • The study of function (activities and processes) Human Anatomy • Anatomy is defined as the study of the human body • Knowledge of anatomy used to: – Organize a patient assessment by body region – Communicate effectively with other members of the health care team Anatomical Position • Best described as a person standing, facing forward, with his palms forward Terminology • • • • Anatomical position Supine Prone Lateral recumbent Anatomic Planes • Anterior – Nearer to or at the front of the body • Posterior – Nearer to or at the back of the body Supine Position Prone Position Left Lateral Recumbent (Recovery Position) Right Lateral Recumbent Trendelenburg Position Fowler’s Position Anatomical Planes • Sagittal plane • Parasagittal • Transverse or horizontal plane • Frontal or coronal plane Body Regions • Right Upper Quadrant – Liver – Gall bladder – Duodenum – Pancreas – Part of colon Body Regions • Left Upper Quadrant – Stomach – Spleen – Left lobe of Liver – Body of Pancreas – Left Kidney and Adrenal Gland – Parts of Colon Body Regions • Right Lower Quadrant – Appendix – Colon – Right Ovary & Fallopian Tube – Right Ureter Body Regions • Left Lower Quadrant – Colon – Left Ovary – Left Fallopian Tube – Left Ureter Abdominal Quadrants Body Cavities • Thoracic cavity • Abdominal cavity • Pelvic cavity Tissues • Connective Connective is a fibrous tissue. It is one of the four traditional classes of tissues. Connective tissue makes up a variety of physical structures including tendons and the connective framework of fibers in muscles, capsules and ligaments around joints, cartilage, bone, adipose tissue, blood and lymphatic tissue. Tissues • Muscle – Tissue that has both the ability to contract and the ability to conduct electrical impulses. Muscles are classified both functionally as either voluntary or involuntary and structurally as either striated or smooth. From this, there emerges three types of muscles: smooth involuntary (smooth) muscle, striated voluntary (skeletal) muscle and striated involuntary (cardiac) muscle. Tissues • Nerve – All living cells have the ability to react to stimuli. Nervous tissue is specialized to react to stimuli and to conduct impulses to various organs in the body which bring about a response to the stimulus. Nerve tissue (as in the brain, spinal cord and peripheral nerves that branch throughout the body) are all made up of specialized nerve cells called neurons. Organ Systems • Organ – A structure made up of two or more kinds of tissues organized to perform a more complex function than can any one tissue alone • System – A group of organs arranged to perform a more complex function than can any one organ alone – Eleven major organ systems compose the human body Integumentary System • Largest organ system of the body • Functions include: – Protection against injury – Prevention of dehydration – Defense against infection – Aid in temperature regulation Integumentary System • • • • • Epidermis Dermis Hair Nails Glands The Skeletal System • Composed of: – Bones – Connective tissues • Cartilage • Tendons • Ligaments Axial Skeleton • Skull – 28 separate bones • Hyoid bone Axial Skeleton • Vertebral column – Consists of 26 bones divided into 5 regions • • • • 7 cervical vertebrae 12 thoracic vertebrae 5 lumbar vertebrae 1 sacral bone – 5 fused vertebrae • 1 coccygeal bone – 5 fused vertebrae Axial Skeleton • Vertebral column – Body – Intervertebral disc – Vertebral arch – Transverse process – Spinous process Thoracic Cage • Protects vital organs in thorax • Prevents collapse of thorax during respiration • 12 pairs of ribs • Sternum – Manubrium – Body – Xiphoid process Appendicular Skeleton • Consists of the bones of the upper and lower extremities and their girdles • Pectoral girdle – Comprised of the scapula and clavicle – Attaches upper limbs to the axial skeleton Upper Extremity • Humerus – Second largest bone in the body • Radius/Ulna • Wrist Pelvic Girdle • Attaches legs to trunk • Consists of two hip bones (coxae) • Acetabulum Femur • Longest bone in body • Head articulates with the acetabulum • Articulates distally with patella Tibia • Tibia – Larger than fibula and supports most of leg's weight – Distal end forms lateral malleolus, forming medial side of ankle joint Fibula • Fibula – Does not articulate with femur – Does articulate with tibia – Distal end forms lateral malleolus, forming lateral aspect of ankle joint Foot • Consists of tarsals, metatarsals, and phalanges • Talus articulates with tibia and fibula • Calcaneus Biomechanics Of Body Movement • Every bone (except the hyoid bone) connects to at least one other bone • Three major classifications of joints – Fibrous joints – Cartilaginous joints – Synovial joints Fibrous Joints • Consist of two bones united by fibrous tissue that have little or no movement • Sutures (seams between flat bones) Fibrous Joints • Syndesmoses • Gomphoses Cartilaginous Joints • Unites two bones by means of hyaline cartilage (synchondroses) or fibrocartilage (symphyses) • Synchondroses • Symphysis Synovial Joints • Contain synovial fluid – Allow movement between articulating bones – Account for most joints of appendicular skeleton • • • • • • Plane or gliding joints Saddle joints Hinge joints Pivot joints Ball-and-socket joints Ellipsoid joints Types of Movement • Flexion/extension Types of Movement • Abduction/adduction Types of Movement • Medial/lateral Types of Movement • Circumduction Types of Movement • Pronation/supination The Muscular System • Primary functions of skeletal muscle: – Movement – Postural maintenance – Heat production Physiology of Skeletal Muscle • Consists of contractile cells (muscle fibers) • Each skeletal muscle fiber is filled with thick and thin myofilaments • Sarcomere - contractile unit of skeletal muscle • Contraction process Skeletal Muscle Movement • Results from muscle contraction by pulling a bone toward another across a movable joint • Points of attachment of each muscle are the origin and insertion • Synergists • Antagonists • Prime mover Types of Muscle Contraction • Classified as either isometric or isotonic • Most muscle movement is a combination of both isometric and isotonic contraction Postural Maintenance • Results from extended periods of muscle tension • Muscle tone is responsible for: – Keeping the back and the legs straight – The head upright – The abdomen flat Heat Production • Chemical reaction from the breakdown of ATP during muscle contraction results in some energy being lost as heat – Largely responsible for normal body temperature • Shivering The Nervous System • A major regulatory and coordinating system of body • Rapidly transmits information by means of nerve impulses from one body area to another Central Nervous System (CNS) • Consists of the brain and spinal cord, which are continuous with each other Peripheral Nervous System (PNS) • Consists of nerves and ganglia • 43 pairs of nerves originate from the CNS to form PNS – 12 pairs originate from brain – 31 pairs originate from spinal cord • Afferent division • Efferent division – Somatic nervous system Autonomic Nervous System • Transmits action potentials from CNS to: – Smooth muscle – Cardiac muscle – Certain glands Central Nervous System • Consists of brain and spinal cord • Major regions of the adult brain: – Brainstem • Medulla • Pons • Midbrain – Diencephalon • Thalamus • Hypothalamus – Cerebrum – Cerebellum Brain Stem • Comprised of medulla, pons, and midbrain • Connects spinal cord to remainder of brain Medulla • Most inferior portion of brain stem • Provides pathway for both ascending and descending nerve tracts • Regulates: – – – – – – – Heart rate Blood vessel diameter Breathing Swallowing Vomiting Coughing Sneezing Pons • Relays information from cerebrum to cerebellum • Houses sleep center and respiratory center • Helps control breathing Midbrain (Mesencephalon) • Smallest region of brain stem • Involved in: – Audio pathways in the CNS – Visual reflexes – Helps regulate coordination of motor activities and muscle tone Cerebrum • Largest portion of brain • Divided into right and left hemispheres • Each hemisphere is divided into lobes named for the bones that lie over them Cerebrum • • • • Frontal lobe Parietal lobe Occipital lobe Temporal lobe Cerebellum • Second largest part of human brain • Major functions – Motor coordination – Compares impulses from motor cortex with those from moving structures – Compares intended movement with actual movement – Responsible for precise movements Spinal Cord • Location and function – Dorsal root – Ventral root – Spinal ganglia • Primary reflex center of the body Meninges • Dura matter • Arachnoid layer • Pia matter The Peripheral Nervous System • Collects information from both inside body and body surface – Relays information by afferent fibers to CNS – Relays information by efferent fibers from CNS to various parts of body Spinal Nerves • First pair exists between skull and first cervical vertebrae • Spinal nerves in sacrum exist in the bone • 8 pairs exist in cervical region • 12 pairs exist in thoracic region • 5 pairs in lumbar region • 5 pairs in sacral region • 1 pair in coccygeal region Dermatomes • Each spinal nerve (except C1) has a specific cutaneous sensory distribution • Dermatome refers to skin surface area supplied by a single spinal nerve Cranial nerves • Sensory functions • Somatomotor functions • Proprioception functions • Parasympathetic functions Autonomic Nervous System • Functions – To maintain or quickly restore homeostasis • Sympathetic and parasympathetic impulses affect body in antagonistic ways The Endocrine System • Hormones – Dissolved in blood plasma and quickly distributed throughout the body The Circulatory System • Blood functions • Blood components – Plasma 55% – Formed elements 45% • Erythrocytes (red blood cells) • Leukocytes (white blood cells) • Thrombocytes (platelets) Heart Anatomy • Muscular pump consisting of four chambers: – Two atria – Two ventricles • Cone-shaped, approximately the size of a closed fist Heart Anatomy • Located in the mediastinum of the thoracic cavity in pericardial cavity – 2/3 of heart's mass lies left of midline of sternum • Pericardium • Coronary vessels Coronary Vessels • Aorta • Pulmonary trunk • Right and left coronary arteries Heart Chambers and Valves • Interatrial septum • Interventricular septum • Atrioventricular (AV) valves – Tricuspid valve – Mitral (bicuspid) valve • Semilunar valves – Aortic and pulmonary semilunar valves Conduction System of the Heart • Sinoatrial (SA) node • Atrioventricular (AV) node / bundle of His • Purkinje fibers Normal Conduction • Sequence of normal impulse conduction – SA node – Both atria • Atrial contraction – AV node – Bundle of His – Purkinje fibers – Both ventricles • Ventricular contraction Blood Flow Through The Heart Peripheral Circulation • Flow of blood: – Ventricles – Arteries – Arterioles – Capillaries – Venous system The Capillary Network • Blood supplied to capillary network by arterioles • Blood flows through network into venules – Flow is regulated by smooth muscle cells (precapillary sphincters) • Major function: – Nutrient and product waste exchange Arteries and Veins • Three layers of elastic tissue comprise all blood vessel walls (except capillaries and venules): – Tunica intima (inner layer) – Tunica media (middle layer) – Tunica adventitia (outer layer) Types of Arteries • Conducting arteries – Large elastic arteries • Distributing arteries – Small to medium-sized arteries • Arterioles – Smallest arteries Venules • Similar in structure to capillaries • Collect blood from capillaries and transport blood to small veins • Nutrient exchange occurs across the walls of venules Veins • Walls are continuous layer of smooth muscle cells • Medium-sized and large veins carry blood to venous trunks and then to the heart • Large veins have valves that allow blood to flow to but not from the heart Arteriovenous Anastomoses (AV shunts) • Allow blood to flow from arteries to veins without passing through capillaries • Natural AV shunts • Pathological shunts Pulmonary Circulation • Blood from right ventricle is pumped into pulmonary trunk • Transport blood to respective lungs • After exchange of oxygen and carbon dioxide: – Two pulmonary veins exit each lung and enter the left atrium Systemic Circulation • Blood enters heart from pulmonary veins • Passes through left atrium into left ventricle and then into aorta • From aorta, blood pumped throughout body Arteries of Systemic Circulation • Aorta • Coronary arteries • Arteries to the head and neck • Arteries of the upper and lower limbs • Thoracic aorta and its branches • Abdominal aorta and its branches • Arteries of the pelvis Veins of Systemic Circulation • Coronary veins • Veins of the head and neck • Veins of the upper and lower limbs • Veins of thorax • Veins of the abdomen and pelvis • Veins of the hepaticportal system Lymphatic System • Considered part of the circulatory system • Consists of a moving fluid that comes from the body and returns to blood • Carries fluid away from tissues Lymphatic System • Functions-aids the immune system in destroying pathogens and filtering waste so that the lymph can be safely returned to the circulatory system. To remove excess fluid, waste, debris, dead blood cells, pathogens, cancer cells, and toxins from these cells and the tissue spaces between them. The lymphatic system also works with the circulatory system to deliver nutrients, oxygen, and hormones from the blood to the cells that make up the tissues of the body. Lymphatic System •Components : A network of thin vessels that branch, like blood vessels, into tissues throughout the body. Lymphatic vessels carry lymph, a colorless, watery fluid originating from interstitial fluid (fluid in the tissues) which is squeezed out of the blood vessels. The lymphatic system transports infection-fighting cells called lymphocytes, is involved in the removal of foreign matter and cell debris by phagocytes and is part of the body's immune system. Airway Anatomy • Respiratory structures are divided by their locations relative to the glottic opening – Upper airway structures located above glottis – Lower airway structures located below glottis Pharynx • Nasopharynx – Uppermost portion of airway, just behind nasal cavities – Nasal septum – Vestibule – Olfactory membranes – Sinuses Pharynx • Oropharynx – Begins at the level of the uvula and extends down to the epiglottis – Opens into the oral cavity Pharynx • Laryngopharynx – Extends from the tip of the epiglottis to the glottis and esophagus – Lined with mucous membrane to protect internal surfaces Larynx • Three main functions: – Air passageway between the pharynx and lungs – Prevents solids and liquids from entering respiratory tree – Involved in speech production Larynx • An outer casing of nine cartilages – Thyroid cartilage – Cricoid cartilage • Only complete cartilaginous ring in larynx – Epiglottis • Hyoid bone • Cricothyroid membrane Larynx • Vestibular folds (false vocal cords) • Vocal cords (true vocal cords) Lower Airway Structures • Trachea • Bronchial tree – Primary bronchi – Secondary bronchi – Bronchioles • Alveoli • Lungs Lungs • Principal function is respiration • Attached to heart by pulmonary arteries and veins • Separated by mediastinum and its contents • Base of each lung rests on the diaphragm • Apex extends 2.5 cm above each clavicle Pleural Cavity • A separate pleural cavity surrounds each lung • Two layers (visceral and parietal) • Pleural space Digestive System • Provides body with water, electrolytes, and other cell nutrients • Specialized to: – Ingest food – Propel food through the GI tract – Absorb nutrients