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the Cell Cycle http://protist.i.hosei.ac.jp/pdb/Images/Sarcodina/Heliozoa/Actinosphaerium/cell_division_1.jpg Cell Division • Cell division is the process where a cell divides to form 2 identical daughter cells • It occurs as part of the cell cycle • Cell division is done for the purposes of: reproduction, growth and repair http://www.healthfiend.com/wp-content/uploads/2011/04/Re-epithelialization-through-cell-division.jpg Cell Division in Multicellular and Unicellular Organisms • In unicellular organisms, cell division results in many new member that are identical to one another through a process called binary fission • In multicellular organisms, cell division helps in the organisms’ development and the repair and renewal of cells Cell Division of DNA • The process of making new cells continues everyday to replace dead and damaged cells • This occurs in somatic cells (body cells or non-sex cells) as oppose to gametes (sex cells) • The process of cell division in somatic cells requires duplicating and separating the DNA, this is called mitosis The Genome • The genome is the all of the cell’s genetic information packaged into DNA • Chromosomes are organized packages of DNA (humans have 46 chromosomes) • DNA are the molecules that contain the genetic codes and instructions of our bodies http://www.accessexcellence.org/RC/VL/GG/images/http://www.genome.gov/Glossary/resources/chromosome_lg_adv.jpg Chromosomes • A duplicated chromosome is made of 2 sister chromatids (identical copies of the chromosome’s DNA) • The region where the strands connect is called the centromere • During synthesis in the cell cycle , the chromosomes are duplicated, to allow for identical genetic information for the new cells http://home.comcast.net/~clupold96/images/notes/chromosomes/chromosome_labeled.gif http://www.uic.edu/classes/bios/bios100/lecturesf04am/realchromo.jpg The Cell Cycle • Interphase - includes 3 subphases • G phase - “First Gap” - growth • S phase - “Synthesis” - chromosome 1 duplication •G phase - “Second Gap” - completes preparation for cell division 2 • M phase - mitosis and cytokinesis (splitting of cytoplasm) http://files5.pdesas.org/123010069062166246171026063048176250062207099255/Download.ashx?hash=2.2 Interphase • Interphase - the cell duplicates organelles and chromosomes and prepares cell for division • This process takes up 90% of the cell cycle Subphases • First Gap - G : Cellular contents are 1 duplicated (not the chromosomes) • Synthesis: chromosomes are duplicated • Second Gap - G : The cell “double checks” 2 the duplicated chromosomes for error, makes repairs as needed •G 0 - cell cycle stops Mitosis • The mitotic phase alternates with the much longer interphase • chromosomes line up in the middle of the nucleus • they are pulled apart at the centromere • this separates them into 2 identical chromatids • 2 nuclei form around the chromosomes and the cell splits in half http://geneticssuite.net/files/Mitosis.jpg