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Chanda Robinson Mitosis vs Meioses How to Use this Tutorial Hello students today’s tutorial is to understand the difference in Mitosis and Meiosis also known as asexual and sexual cell reproduction. To find your way through this tutorial, is easy. You will use your mouse to click on the buttons at the bottom of the screen: To return to the beginning of the tutorial, click on the Home button. To go to the previous page click the arrow pointing To move to the next page, click the next arrow button. You will hear a click each time you click your mouse on the arrow. There will be self checks along the way to evaluate (check for understanding) your progress. Happy Learning Understanding Mitosis Mitosis is defined as the process, in the cell cycle, by which a cell duplicates into two genetically identical daughter homologous cells. This means that the cells has the same shape, same types of genes in the same location, everything matches up. In mitosis, chromosomes in the cell nucleus are separated into two identical sets of chromosomes, each in its own nucleus.. The best way to remember the phases of Mitosis is to create an Acronym. Below is an acronym to help you remember the correct order of mitosis. However one will still need to know what happens in each phase to identify the difference in mitosis and meiosis the two process in cell division. Interphase = In Prophase= Professional Mataphase = Martial Anaphase = Arts you Telephase = Take Cytokinesis= Chances Now that I know the phases what all is involved in mitosis? Understanding Mitosis Cont. One single stain of DNA is called a haploid- when a cell has only one set of chromosome. That single strain of DNA can also be called a chromatid or a gametes in sex cells. In the second picture there are two stains of DNA which are twisted together which is called a diploid. When two gametes form a diploid zygot they have (2n) which is twice the number of chromosomes. Another example of how this DNA looks is below. A cell has a certain number of chromosomes. Each strain or chromatid is held together by a little circle in the middle called a centromere . How does this fit in with mitosis? . Understanding Mitosis Cont. Another way to remember information concerning mitosis is that it has to be with my body. These cells regenerate to help the body heal and repair itself. So if you scrape your knee skin cells are going to reproduce themselves to heal your scraped knee. It will reproduce the same exact cell over and over until your knee is healed. Meaning it will look like it did before you hurt yourself. Below are the phases of mitosis and what each stage looks like. The colored picture is the end result of mitosis. Interphase is the first phase and the longest phase of the cell cycle. This is the stage where DNA copies itself. The cell is growing during this stage During the next the chromatin condenses into double rod-shaped structures called chromosomes in which the chromatin becomes visible. This is called Phrophase. Next is Metaphase where the chromatin align in the middle of the cell. The spindle fibers attach to the centromeres that hold the chromatids together. This is the process before the separation into two daughter cells. Next during Anaphase the chromosomes break at the centromeres. Basically there are pulled apart this is the shortest phase of Mitosis. The next to the last phase is called Telophase when the nuclear membrane re-forms around the chromosomes. The nucleolus reforms and the cell begins to split into two cells. Lastly two new daughter cells are created and this stage is called cytokinesis.. See below for each step and phase. Check for understanding Before we move on to sexual reproduction or meiosis let’s check to make sure we are on track. A. Asexual Reproduction will result in 1. 2 cells with the same DNA 2. 1 cell with different DNA 3. 2 new cells with totally different DNA in each cell 4. A cell B. A single strain of DNA is called a 1.A zygot 2.A chromatid 3.Cell 4.Sex cell C. The correct order of Mitosis is 1.Cytokinesis, Anaphase, Telephase, Prophase, Paraphrase and Interphase 2.Interphase, Prophase, Cytokinesis, Telephone, Anaphase and Mataphase 3.Interphase, Prophase, Metaphase, Anaphase, Telephase and Cytokinesis 4.Prophase, Interphase, Anaphase, Metaphase, Cytokinesis, and Telephase Check for understanding Before we move let’s make sure that you selected the correct answers to the questions. The correct answer is written in red. A. Asexual Reproduction will result in 1. 2 new cells with the same DNA 2. 1 cell with different DNA 3. 2 new cells with totally different DNA in each cell 4. A cell B. A single strain of DNA is called a 1.A zygot 2.A chromatid 3.Cell 4.Sex cell C. The correct order of Mitosis is 1.Cytokinesis, Anaphase, Telephase, Prophase, Paraphrase and Interphase 2.Interphase, Prophase, Cytokinesis, Telephone, Anaphase and Mataphase 3.Interphase, Prophase, Metaphase, Anaphase, Telephase and Cytokinesis 4.Prophase, Interphase, Anaphase, Metaphase, Cytokinesis, and Telephase How did you do? Great lets move on Understanding Meiosis The process of meiosis produces two daughter cells from a parent cell. An easy way to look at this is to think of you. In order to create you there was a mom and a dad which are called parents. In meiosis a mom cell which has ½ of the DNA and the dad cell has ½ of the DNA. During meioses there will be a unique (not identical) cell created from the parent cell. Think about your brothers and sisters although you may have the same parents you have a unique (not like theirs) appearance. Because there is a mom and dad cell that produce an offspring these are called sex cells or gametes (i.e. eggs and sperm). Because they are produced from sperm cells, gametes are likewise haploid. At the end of this process there should be four unique daughter cells created. Unlike mitosis meioses does not begin at interphase. That step has already been complete in the parent cell before reproduction begins. Since Meiosis needs two cells all of the steps of mitosis have already taken place. In meioses there are not any new phase names just replications of the mitosis steps but happening at the same time in two parent cells. Therefore after Interphase, Prophase, Metaphase, Anaphase, Telephase and Cytokinesis the phases continue with Prophase II, Metaphase II, Anaphase II, Telephase II and at the end of these phases there are 4 hypoid cells created. But what happens during each phase ? Understanding Meiosis Cont. To remember the phases of Meiosis this acronym may help: Prophase II= Please Mataphase II = Make Anaphase II = Anchovie Telephase II = Tacos During Prophase II the chromosomes will not copy in further, however the spindle fibers appear and the nuclei and nuclear membranes have broken apart. In Metaphase II the chromosomes begin migrating (moving) to the equator (the middle) of both cells. Once the chromosomes have lined up at the cell’s center the fibers of the sister chromtaids (remember that is a part of a chromosome) begin to point towards the opposite poles. The sister chromtaids separate (break apart) and start to migrate to the ends of both cells anaphase II is complete. At this time each is now a chromosome and the new cells are ready to begin to split. In telophase II The nuclui has formed around each new chromosome and four haploid (single stain of DNA) cells have been formed. Check for understanding 1. What phases do not occur during Meiosis? a. Phropase II b. Interphase and Cytokensis c. Metaphase and Anaphase II d. Telophase II and Metaphase II 2. How many cells will be created at the end of Meiosis a. 4 hyploid unique cells b. 4 heterogeneous cells c. 3 chromosomes cells d. 2 chromtaid cells 3. During Meioses the nuclui does not form around new cells. a.True b.False c. Not sure D, What is a nuclui? 4. A _______ is a sex cell? a. Gamete b. Hyploid c. Egg d. Centromere Let’s see what you got right l Checking for understanding cont. 1. What phases do not occur during Meiosis? a. Phropase II b. Interphase and Cytokensis c. Metaphase and Anaphase II d. Telophase II and Metaphase II 2. How many cells will be created at the end of Meiosis a. 4 hyploid unique cells b. 4 heterogeneous cells c. 3 chromosomes cells d. 2 chromtaid cells 3. During Meioses the nuclui does not form around new cells. a.True b.False c. Not sure D, What is a nuclui? 4. A _______ is a sex cell? a. Gamete b. Hyploid c. Egg d. Centromere I know that you got them all right. Lets look at a quick review. One last check for understanding cont. 1. Mitosis cell division is asexual reproduction ? a. fales b. true c. Could be d. Maybe note 2. Production of a unique cell is done during a. meiosis b. interphase c. chromsome d. mitosis 3. Mitosis helps to heal my body. a.True b.False c. Not sure D, What is a mitosis? 4. A _______ is a body cell? a. somatic b. Hyploid c. Egg d. Centromere One last check for understanding cont. 1. Mitosis cell division is asexual reproduction ? a. fales b. true c. Could be d. Maybe note 2. Production of a unique cell is done during a. meiosis b. interphase c. chromsome d. mitosis 3. Mitosis helps to heal my body. a.True b.False c. Not sure D, What is a mitosis? 4. A _______ is a body cell? a. somatic b. Hyploid c. Egg d. Centromere A quick comparison Mitosis Meiosis Repairs my body ½ mom+ ½ dad Identical to mom cell unique cell Asexual Sexual Diploid 2n Haploid shared chromosomes I, P, M, A, T, C Interphase, Phrophase, Metaphase, Anaphase, Telophase, Cytkensis I, P,M,A,T,C I & P,M,A,T II Interphase I, Phrophase I, Metaphase I, Anaphase I, Telophase I, CytkensisI &, Phrophase II, Metaphase II, Anaphase II, Telophase II, 2 cells 4 cells Heterogeneous Homologous Somatic (body cells) Gamets (sex cells) Congratulations you completed the tutorial on Mitosis and Meiosis