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Advanced Biology
Connective Tissue
Found
body
everywhere in
Connective
Cartilage
Bone
Blood
Tissue Proper
Binding
and Support
Protection
Insulation
Transportation
Embryonic
Tissue where
all other types arise from
Cartilage
– avascular
Dense – poor
vascularization
All others have rich
supply
Non-living
Allows
for weight
bearing, great tension,
endures abrasion
GROUND
Amorphous
– unstructured
Interstitial fluid
Cell adhesion proteins –
fibronectin and laminin
=glue
GROUND
Holds
fluid
Acts as a sieve, or
medium through which
nutrients diffuse
FIBERS
Provide
support
COLLAGEN
Made
of protein collagen
Very tough, ability to resist
longitudinal stress
Appear white – white fibers
ELASTIC
Made
of protein elastin
Stretch and recoil (rubber
band)
Skin, lungs
Appear yellow – yellow
fibers
RETICULAR
Fine
collagenous
Branch extensively, form
networks surrounded by BV
Found where CT meets
other tissues
CELLS
-blast
= immature
-cyte= mature
FIBROBLAST
Immature
connective
tissue proper
CHONDROBLAST
Immature
cartilage
OSTEOBLAST
Immature
bone cell
HEMOCYTOBLAST
Immature
blood cell
WHITE BLOOD CELLS
Neutrophils
Eosinophils
Lymphocytes
PLASMA CELLS
Produce
Antibodies
MAST CELLS
 Clustered
in tissue spaces
 Detect foreign substances, initate
inflammatory response
 Heparin – anticoagulant (free in
blood stream)
 Histamine – makes capillaries leaky
MACROPHAGES
 Large,
irregular shaped –
phagocytize foreign material
 All have certain roles:
Histiocytes  Kupffer cells – liver
 Microglial – brain
EMBRYONIC
1st
Definitive Layer
Layer from which all others
differentiate
Temporary – Wharton’s Jelly
which supports umbilical
cord
CONNECTIVE TISSUE
PROPER
Loose
Dense
Loose
= Areolar,
Adipose, Reticular
Dense = Dense regular,
Dense irregular, elastic