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The National Heart, Lung, and Blood Institute Pediatric Circulatory Support Program by J. Timothy Baldwin, Harvey S. Borovetz, Brian W. Duncan, Mark J. Gartner, Robert K. Jarvik, and William J. Weiss Circulation Volume 123(11):1233-1240 March 22, 2011 Copyright © American Heart Association, Inc. All rights reserved. The family of devices developed under the Pediatric Circulatory Support Program. J. Timothy Baldwin et al. Circulation. 2011;123:1233-1240 Copyright © American Heart Association, Inc. All rights reserved. Platelet activation in a lamb animal model using an earlier version of the PediaFlow ventricular assist system after stimulation of blood with 20 μmol/L adenosine diphosphate (ADP) and 10 μmol/L platelet activating factor (PAF). J. Timothy Baldwin et al. Circulation. 2011;123:1233-1240 Copyright © American Heart Association, Inc. All rights reserved. Model of the PediPump in a right ventricular assist device (RVAD) configuration virtually positioned on the diaphragmatic surface of the heart in a 3-dimensional reconstruction derived from a computed tomography scan of an 8-month-old patient with tetralogy of Fallot. J. Timothy Baldwin et al. Circulation. 2011;123:1233-1240 Copyright © American Heart Association, Inc. All rights reserved. The cone bearing developed for the infant and child Jarvik 2000 ventricular assist device (VAD). J. Timothy Baldwin et al. Circulation. 2011;123:1233-1240 Copyright © American Heart Association, Inc. All rights reserved. An example of a flow map (A) and the corresponding wall shear rate map (B). J. Timothy Baldwin et al. Circulation. 2011;123:1233-1240 Copyright © American Heart Association, Inc. All rights reserved. Left, The heparin dose in the reduced-heparin thromboelastography protocol (TEG) group was approximately one half that of the activated partial thromboplastin time (aPTT) group, and circulating heparin (anti-factor Xa [antiXa]) was barely detectable in the TEG group. J. Timothy Baldwin et al. Circulation. 2011;123:1233-1240 Copyright © American Heart Association, Inc. All rights reserved.