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Fibrin-based clot formation as an early and rapid
biomarker for progression of postpartum hemorrhage: a
prospective study
by Peter W. Collins, Graeme Lilley, Daniel Bruynseels, David Burkett-St. Laurent,
Rebecca Cannings-John, Elizabeth Precious, Vincent Hamlyn, Julia Sanders, Raza
Alikhan, Rachel Rayment, Alexandra Rees, Abigail Kaye, Judith E. Hall, Shantini
Paranjothy, Andrew Weeks, and Rachel E. Collis
Blood
Volume 124(11):1727-1736
September 11, 2014
©2014 by American Society of Hematology
The women recruited into the study are shown compared with the number of women delivered
during the study period as reported in the Cardiff Maternity Database. *The number of women
experiencing bleeds of ≥2000 mL among all women delivering during the study ...
Peter W. Collins et al. Blood 2014;124:1727-1736
©2014 by American Society of Hematology
ROC curves for fibrinogen and Fibtem A5.
Peter W. Collins et al. Blood 2014;124:1727-1736
©2014 by American Society of Hematology
Time of bleeds and stay on HDU. (A) Time from the recognition of abnormal bleeding to
hemostatic control.
Peter W. Collins et al. Blood 2014;124:1727-1736
©2014 by American Society of Hematology
The time to first unit of RBC, fourth unit of RBC, and first unit of FFP. (A-C) All women in the
study.
Peter W. Collins et al. Blood 2014;124:1727-1736
©2014 by American Society of Hematology
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