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Chapter 9: Muscular System I. Structure of a Skeletal Muscle A. Introduction 1. A__________________________________ is an organ of the skeletal system. 2. A skeletal muscle is composed of ____________________________________ B. Connective Tissue Coverings 1. Fascia is ________________________________________________________ 2. A tendon is ______________________________________________________ 3. Tendons connect a muscle to ________________________________________ 4. An aponeurosis is _________________________________________________ 5. Epimysium is ____________________________________________________ 6. Perimysium is____________________________________________________ 7. A fascicle is _____________________________________________________ 8. Endomysium is___________________________________________________ 9. Deep fascia is ____________________________________________________ 10. Subcutaneous fascia is ____________________________________________ 11. Subserous fascia is _______________________________________________ C. Skeletal Muscle Fibers 1. A skeletal muscle fiber is a single ____________________________________ 2. The sarcolemma is ________________________________________________ 3. The sarcoplasm is _________________________________________________ 4. The sarcoplasm contains ___________________________________________ 5. Myofibrils are _________________ and are located in the ________________ 6. Myofibrils play a fundamental role in _________________________________ 7. Thick myofilaments are composed of _________________________________ 8. Thin myofilaments are composed of __________________________________ 9. The organization of myofilaments produce _____________________________ __________________________________________________________________ 10. A sarcomere is __________________________________________________ 9-1 11. Myofibrils may be thought of as _____________________ joined end to end. 12. I bands are composed of __________________________________________ 13. Z lines are ______________________________________________________ 14. A bands are composed of __________________________________________ 15. The H zone is ___________________________________________________ 16. The M line is ___________________________________________________ 17. Titin connects ___________________________________________________ 18. A sarcomere extends from one _____________________________________ 19. Each myosin molecule consists of ___________________________________ __________________________________________________________________ 20. Thin filaments consist of double ____________________________________ 21. Actin has a binding site to which ___________________________ can attach. 22. Troponin and tropomyosin associate with _____________________________ 23. Sarcoplasmic reticulum is _________________________________________ 24. Transverse tubules are ____________________________________________ 25. Cisternae are____________________________________________________ 26. A triad is formed by ______________________________________________ II. Skeletal Muscle Contraction A. Neuromuscular Junction 1. Each skeletal muscle is connected to __________________________________ 2. A motor neuron passes out from _____________________________________ 3. Normally, a skeletal muscle fiber contracts only upon ____________________ __________________________________________________________________ 4. A neuromuscular junction is ________________________________________ 5. A motor end plate is _______________________________________________ 6. A motor unit is ___________________________________________________ 7. A synaptic cleft separates___________________________________________ 8. Synaptic vesicles store _____________________________________________ 9-2 B. Stimulus for Contraction 1. __________________________ is the neurotrasnmitter that motor neurons use to control skeletal muscle. 2. ACh is synthesized in the cytoplasm of ________________________________ and is stored in _____________________________________________________ 3. When a nerve impulse ________________________ , acetylcholine is released into the synaptic cleft. 4. ACh combines with ____________________________ on the motor end plate, and stimulates ______________________________________________________ 5. A muscle impulse is _______________________________________________ 6. A muscle impulse changes __________________________________________ 7. Ultimately the muscle impulse reaches ________________________________ C. Excitation Contraction Coupling 1. The sarcoplasmic reticulum has a high concentration of ___________________ 2. In response to a muscle impulse, the membranes ________________________ ___________________________, and the calcium ________________________ __________________________________________________________________ 3. When a muscle fiber is at rest, ________________________ block the binding sites on the actin molecules. 4. Calcium ions bind to ____________________, changing its _______________ and altering ________________________________________________________ 5. The movement of the tropomyosin molecule exposes _____________________ __________________________, allowing________________________________ D. The Sliding Filament Theory 1. The functional unit of skeletal muscles is ______________________________ 2. According to the sliding filament theory, when sarcomeres shorten, _________ __________________________________________________________________ 3. As contraction occurs, ________________ and ______________ get narrower and _____________________________________________ move closer together. 9-3 E. Cross-bridge Cycling 1. The force that shortens the sarcomeres comes from ______________________ __________________________________________________________________ 2. A myosin cross-bridge attaches to actin in order to _______________________ __________________________________________________________________ 3. The cross-bridge can release, straighten, and combine with ________________ __________________________________________________________________ 4. Myosin cross-bridges contain the enzyme ______________________________ 5. ATPase catalyzes _________________________________________________ 6. The force for muscle contraction is provided by _________________________ __________________________________________________________________ 7. Breaking down of ATP puts the myosin cross-bridge in a __________position. 8. When a muscle is stimulated to contract, a ____________________ attaches to ___________________________ and pulls ______________________________ , shortening the ______________________________________________________ 9. When another ATP binds, the ______________________________ is released, then breaks down the ____________________to return to ___________________ 10. The cross-bridge cycle may repeat over and over as long as _______________ __________________________________________________________________ F. Relaxation 1. In order for a muscle fiber to relax, acetylcholine must be decomposed by an enzyme called ______________________________________________________ 2. The action of acetycholinesterase prevents _____________________________ __________________________________________________________________ 3. When acetylcholine is broken down, __________________________________ ____________________________________________________________ ceases. 4. The calcium pump moves calcium ___________________________________ __________________________________________________________________ 5. When calcium is removed from the cytoplasm, the _______________________ break and _____________________________________ rolls back into its groove, preventing _________________________________________________________ 9-4 6. ATP is necessary for both muscle ____________________________________ and _______________________________________________________________ 7. The trigger for contraction is ________________________________________ G. Energy Sources for Contraction 1. Creatine phosphate is ______________________________________________ 2. Creatine phosphate contains ________________________________________ 3. As ATP is decomposed to ADP, the energy from ________________________ is transferred back to ________________________________________________ 4. After creatine phosphate is used, a muscle cell must depend on _____________ _________________________________________________ as a source of energy for synthesizing _____________________________________________________ 5. Typically a muscle stores glucose in the form of ________________________ H. Oxygen Supply and Cellular Respiration 1. Glycolysis occurs _______________________ and is ____________________ 2. Glycolysis releases a few ___________________________________________ 3. The complete break down of glucose occurs in __________________________ and requires ________________________________________________________ 4. The citric acid cycle and electron transport chain produce _________________ __________________________________________________________________ 5. Oxygen is carried in the blood stream bound to _________________________ 6. Myoglobin is _____________________________________________ in color. 7. Myoglobin stores ___________________________________ in muscle tissue. I. Oxygen Debt 1. Lactic acid threshold is ____________________________________________ 2. Under anaerobic conditions, glycolysis breaks down glucose into ___________ and converts it to ____________________________________________________ 3. Lactic acid is carried by the blood to the _______________________________ 4. Liver cells can convert lactic acid to __________________________________ 5. Oxygen debt reflects ______________________________________________ __________________________________________________________________ 9-5 J. Muscle Fatigue 1. Fatigue is _______________________________________________________ 2. Fatigue may result from ____________________________________________ __________________________________________________________________ 3. A cramp is ______________________________________________________ 4. Physically fit people make less lactic acid because _______________________ __________________________________________________________________ K. Heat Production 1. Heat is a by-product of_____________________________________________ 2. Blood transports heat _____________________________________________ , which helps ________________________________________________________ III. Muscle Responses A. Introduction 1. One way to observe muscle contraction is to____________________________ __________________________________________________________________ 2. An________________________ is usually used to produce muscle contraction. B. Threshold Stimulus 1. Threshold stimulus is ______________________________________________ 2. An impulse in _______________________________ normally releases enough ______________________ to bring the muscle fibers in its __________________ to ________________________________________________________________ C. Recording a Muscle Contraction 1. A twitch is ______________________________________________________ 2. A myogram is ____________________________________________________ 3. Three periods of a muscle fiber contraction are__________________________ __________________________________________________________________ 4. During the period of contraction, a muscle fiber is _______________________ __________________________________________________________________ 5. The latent period is________________________________________________ 6. The period of relaxation is __________________________________________ 7. The refractory period is ____________________________________________ 9-6 8. An all-or-none response is __________________________________________ __________________________________________________________________ 9. The length to which a muscle is stretched before stimulation affects _________ __________________________________________________________________ 10. If a muscle is stretched well beyond its normal resting length, the force will __________________________________________________________________ 11. At very short muscle lengths, the sarcomere becomes ___________________ and ___________________________________________________ is not possible. 12. In the whole muscle, the degree of tension reflects ______________________ __________________________________________________________________ D. Summation 1. Twitches in a muscle can combine to become ___________________________ 2. Summation is ____________________________________________________ 3. Tetanic contractions are ____________________________________________ E. Recruitment of Motor Units 1. The _______________ in the motor units, the more ______________________ the movements can be produced in a particular muscle. 2. All muscle fibers in a motor unit are stimulated at __________________ time. 3. Multiple motor unit summation is ____________________________________ 4. Recruitment is ___________________________________________________ 5. As the intensity of stimulation increases, ______________________________ continues until all possible motor units are activated in a muscle. F. Sustained Contractions 1. During sustained contractions, ________________ tend to be recruited earlier. 2. The larger motor units respond ______________________________________ and more __________________________________________________________ 3. Muscle movements are smooth because _______________________________ __________________________________________________________________ 4. Muscle tone is ___________________________________________________ 5. Muscle tone is important for maintaining ______________________________ 9-7 G. Types of Contractions 1. An isotonic contraction is __________________________________________ 2. A concentric contraction is _________________________________________ 3. An eccentric contraction is__________________________________________ 4. An isometric contraction is _________________________________________ 5. An example of an isometric contraction is _____________________________ 6. An example of an isotonic contraction is _______________________________ H. Fast and Slow Twitch Muscle Fibers 1. Type I fibers are __________________________________________________ 2. Examples of type I fibers are ________________________________________ 3. Type I fibers are _________________ in color because ___________________ __________________________________________________________________ 4. Type I fibers are resistant to_________________________________________ 5. Type IIa fibers are ________________________________________________ 6. Type IIa fibers are ________________ in color because __________________ __________________________________________________________________ 7. Type IIb fibers are ________________________________________________ 8. A muscles contain ____________________________________ of fiber types. IV. Smooth Muscles A. Smooth Muscle Fibers 1. Compared to skeletal muscle fibers, smooth muscle fibers _________________ __________________________________________________________________ 2. Two major types of smooth muscle are ________________________________ __________________________________________________________________ 3. Multiunit smooth muscle is located ___________________________________ __________________________________________________________________ 4. Visceral smooth muscle is located ____________________________________ __________________________________________________________________ 5. Fibers of visceral smooth muscle are connected by_______________________ 6. Rhythmicity is ___________________________________________________ 7. Peristalsis is _____________________________________________________ 9-8 8. Peristalsis helps force ______________________________________________ B. Smooth Muscle Contraction 1. Compared to skeletal muscle fibers, smooth muscle fibers lack _____________ and use _______________________________________ to bind calcium instead. 2. Two neurotransmitters that affect smooth muscle are _____________________ __________________________________________________________________ 3. Hormones affect smooth muscle by___________________________________ __________________________________________________________________ 4. Stretching of smooth muscle can trigger _______________________________ 5. Smooth muscle is _________________ to contract and ___________________ to relax than skeletal muscle. 6. Unlike skeletal muscle, smooth muscle fibers can change length without changing __________________________________________________________ V. Cardiac Muscle A. Cardiac muscle appears only in ___________________________________________ B. Cardiac muscle is composed of _______________________________________ cells, forming fibers that are ______________________________________________________ C. Cardiac muscle fibers can contract ___________________ then skeletal muscle fibers. D. Intercalated discs are ____________________________________________________ E. Intercalated discs allow muscle impulses to __________________________________ F. A syncytium is _________________________________________________________ VI. Skeletal Muscle Actions A. Introduction 1. Skeletal muscles generate __________________________________________ 2. The action of each muscle mostly depends upon_________________________ __________________________________________________________________ B. Origin and Insertion 1. The origin of a muscle is ___________________________________________ 2. The insertion of a muscle is _________________________________________ 3. When a muscle contracts, its ________________________________________ is pulled toward its __________________________________________________ 9-9 4. The head of a muscle is ____________________________________________ 5. The origins of the biceps brachii are __________________________________ 6. The insertion of the bicep brachii is ___________________________________ 7. When the biceps brachii contracts, the __________________________ bends. C. Interaction of Skeletal Muscles 1. A prime mover is _________________________________________________ 2. A synergist is ____________________________________________________ 3. An antagonist is __________________________________________________ VII. Major Skeletal Muscles A. Introduction 1. The name of a muscle may reflect ____________________________________ __________________________________________________________________ 2. An example of a muscle named for it size is ____________________________ 3. An example of a muscle named for its shape is __________________________ 4. An example of a muscle named for its function is________________________ 5. An example of a muscle named for its number of origins is ________________ 6. An example of a muscle named for its attachments site is _________________ __________________________________________________________________ 7. An example of a muscle named of the direction of its muscle fibers is _______ __________________________________________________________________ B. Muscles of Facial Expression 1. As a group, muscles of facial expression connect ________________________ __________________________________________________________________ 2. For the following muscles, list their origins, insertions, and actions. Epicranius Orbicularis oculi Orbicularis oris Buccinator Zygomaticus Platysma 9-10 C. Muscles of Mastication 1. Muscles of mastication produce____________________________ movements. 2. For the following muscles, list their origins, insertions, and actions Masseter Temporalis Medial pterygoid Lateral pterygoid D. Muscles That Move the Head and Vertebral Column 1. For the following muscles, list their origins, insertions, and actions Sternocleidomastoid Splenius capitis Semispinalis capitis Erector spinae E. Muscles That Move the Pectoral Girdle 1. For the following muscles, list their origins, insertions, and actions Trapezius Rhomboideus major Levator spinae Serratus anterior Pectoralis major F. Muscles That Move the Arm 1. For the following muscles, list their origins, insertions, and actions Coracobrachialis Pectoralis major Teres major Latissimus dorsi Supraspinatus Deltoid Subscapularis Infraspinatus Teres minor 9-11 G. Muscles That Move the Forearm 1. For the following muscles, list their origins, insertions, and actions Biceps brachii Brachialis Brachioradialis Triceps brachii Supinator Pronator teres Pronator quadratus H. Muscles That Move the Hand 1. For the following muscles, list their origins, insertions, and actions Flexor carpi radialis longus Flexor carpi ulnaris Palmaris longus Flexor digitorum profundus Flexor digitorum superficialis Extensor carpi radialis Extensor carpi radialis brevic Extensor carpi ulnaris Extensor digitorum I. Muscles of the Abdominal Wall 1. The linea aspera is ________________________________________________ 2. For the following muscles, list their origins, insertions, and actions External oblique Internal oblique Transversus abdominis Rectus abdominis J. Muscles of the Pelvic Outlet 1. The pelvic diaphragm forms ________________________________________ 2. The urogenital diaphragm fills _______________________________________ 3. For the following muscles, list their origins, insertions, and actions 9-12 Levator ani Coccygeus Superficial transversus perinea Bulbospongiosus Ischiocavernosus Sphincter urethra K. Muscles That Move the Thigh 1. For the following muscles, list their origins, insertions, and actions Psoas major Iliacus Gluteus maximus Gluteus medius Gluteus minimus Pectineus Adductor longus Adductor magnus Gracilis L. Muscles That Move the Leg 1. For the following muscles, list their origins, insertions, and actions Biceps femoris Semitendinosus Semimembranosus Sartorius Quadriceps femoris group M. Muscle That Move the Foot 1. For the following muscles, list their origins, insertions, and actions Tibialis anterior Fibularis tertius Extensor digitorum longus Gastrocnemius Soleus 9-13 Flexor digitorum longus Tibialis posterior Fibularis longus VIII. Life-Span Changes A. Signs of aging of the muscular system begin to appear _________________________ B. At a microscopic level, ___________________________________________ decline. C. _______________________________________ being to replace some muscle tissue. D. _________________________________ can help maintain a healthy muscular system E. According to the National Institute on Aging, exercise should include _____________ ________________________________________________________________________ 9-14