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COPD - UniNursety
COPD - UniNursety

... This document synthesizes traditional infection control and industrial hygiene approaches to enhancing protection of health care personnel during an influenza pandemic. It emphasizes that surgical mask and respirator use are components of a system of infection control practices to prevent the spread ...
Developments in the Care of Influenza Patients
Developments in the Care of Influenza Patients

... pulmonary disease (COPD), and emphysema account for 82% of the pulmonary diagnoses associated with acute respiratory disease [14]. In a recent study of influenza vaccination in elderly members of a managed care organization who had chronic lung disease, vaccination was associated with a 52% reductio ...
The Global Influenza Hospital Surveillance
The Global Influenza Hospital Surveillance

... annually; 5–10% of adults and 20–30% of children will show some clinical manifestation and resulting in about 3–5 million cases of severe illness, and about 250 000–500 000 deaths.1–4 Influenza illness can result in hospitalization and death mainly among high-risk groups, but also in a substantial p ...
Strategies to increase influenza uptake among health care workers
Strategies to increase influenza uptake among health care workers

... Maltezou HC, Drancourt M. Nosocomial influenza in children. Journal of Hospital Infection 2003;55:83-91 Meara et al. Influenza A outbreak in a community hospital. Ir Med J 2006;99: 175-177 ...
Why Was the 1918 Influenza So Deadly?
Why Was the 1918 Influenza So Deadly?

... Americans as did the 1957 Asian flu and 20 times as many as the 1968 Hong Kong influenza (Webster, 2001). Was there something special about the biology of the 1918 influenza virus that made it particularly virulent and deadly? Or did the conditions in which people lived at the end of the First World ...
Neuraminidase inhibitors as anti
Neuraminidase inhibitors as anti

... significant increase in the NA activity, as demonstrated by the 3-pentyl analogue 8 (GS 4071). This result strongly suggested that there may be two hydrophobic pockets oriented in two different directions for the binding of the R group in 18. The crystal structure of 8 (GS 4071) complexed with NA (F ...
Wednesday, August 26/09
Wednesday, August 26/09

... admitted to an intensive care unit (ICU) had been reported to the Public Health Agency of Canada. This week, four new deaths were reported for a total of 70 deaths since the beginning of the pandemic. 90% of the hospitalized cases and more than 85% of the deaths have been reported by only 4 province ...
Influenza
Influenza

... 17. Health-EU: Influenza - Official EU public health portal set up to encourage the coordination of member states in their response to influenza A(H1N1) responsible for the current pandemic. 18. Healthscribes: Influenza - Provides information on flu, causes, symptoms, diagnosis, treatment, side effe ...
ATAGI Influenza Vaccine Statement
ATAGI Influenza Vaccine Statement

... Importance of influenza vaccination for pregnant women Influenza vaccination is strongly recommended for pregnant women, and it is safe to administer influenza vaccine during any stage of pregnancy. Influenza vaccination will reduce the risk of complications from influenza in both the pregnant woman ...
Early 2016/17 vaccine effectiveness estimates
Early 2016/17 vaccine effectiveness estimates

... older and target groups for vaccination were low and, despite low precision, reinforce the risk assessment from the European Centre for Disease Prevention and Control (ECDC), which suggests to consider administering antiviral drugs to populations vulnerable to severe influenza irrespective of vaccin ...
Press Kit Seasonal Flu
Press Kit Seasonal Flu

... S EA SO NAL I NFL UE NZA P RES S KI T ...
Influenza burden of illness, diagnosis, treatment, and prevention
Influenza burden of illness, diagnosis, treatment, and prevention

... in the UK. These recommendations include persons aged 65 years and over, persons with chronic conditions of the lungs, heart, or kidneys, diabetes mellitus, immunosuppression, and anyone living in long term residential accommodation. Children with high risk conditions are included,7 62 but ...
www.ephysician.ir - Electronic Physician Journal
www.ephysician.ir - Electronic Physician Journal

... flu within two years (2) and India is no exception. It ranked 3rd most affected country for cases and deaths of swine flu globally (5) and it is probably one of the most appalling words in Gujarat, especially in Vadodara because people equate H1N1 flu with death due to very high case fatality rate. ...
Influenza
Influenza

... If considering using antiviral medication check the HPSC website to ascertain if influenza is circulating and only use antivirals if this is confirmed. Antivirals such as neuraminidase inhibitors can be used for treatment and prophylactic purposes during influenza outbreaks. Indications for prophyla ...
Social distancing evidence summary
Social distancing evidence summary

... affected may reduce the risk of acquisition of severe influenza symptoms among employees by about 30%.34 Direct costs of working from home are likely to be moderate or variable,9 but this has not been studied well. These costs could result from instituting sick leave policies, maintaining business c ...
Information
Information

... better faster. They may also prevent serious flu complications. For treatment, antiviral drugs work best if started soon after getting sick (within 2 days of symptoms). How long can an infected person spread swine flu to others? ...
Recommended composition of influenza virus vaccines for use in
Recommended composition of influenza virus vaccines for use in

... characteristics of A(H1N1)pdm09 viruses were assessed with panels of post-infection ferret antisera and human paediatric, adult and older adult pre- and post-vaccination sera in haemagglutination inhibition (HI) assays. HI assays with ferret antisera indicated that almost all recent A(H1N1)pdm09 vir ...
$doc.title

... Control and Prevention (CDC) and other Administration officials refer to it as 2009 H1N1 flu. Throughout this report, the virus is referred to as H1N1. Although H1N1 does not appear to be as lethal as H5N1 avian influenza, which reemerged in 2005, the virus is slightly more lethal than seasonal flu ...
Influenza and Community-acquired Pneumonia Interactions: The
Influenza and Community-acquired Pneumonia Interactions: The

... infection with influenza by interleukin-10 (26) and inhibition of the pulmonary system’s ability to fight infection by interferon-gamma (27, 28), that provide testable hypotheses for an inflammatory response that might occur in humans. Further, in animal studies, investigators can explore what combi ...
Richard E. Besser, MD Acting Director Centers for Disease Control and Prevention
Richard E. Besser, MD Acting Director Centers for Disease Control and Prevention

... authorized to be distributed under this EUA. Such products are authorized to be distributed or dispensed without the requisite prescription label information under section 503(b)(2) of the Act (e-g., name and address of dispenser, serial number, date of prescription or of its filling, name of prescr ...
Pandemic Influenza Risk Communication Excerpt
Pandemic Influenza Risk Communication Excerpt

... A pandemic, or worldwide outbreak of a new influenza virus, could dwarf this impact by overwhelming our health and medical capabilities, potentially resulting in hundreds of thousands of deaths, millions of hospitalizations, and hundreds of billions of dollars in direct and indirect costs. This Stra ...
BRIEFING PAPER Southern Hemisphere Influenza Vaccine
BRIEFING PAPER Southern Hemisphere Influenza Vaccine

... The
NIC
provides
influenza
virus
isolates
to
the
WHO
Global
Influenza
Surveillance
Network
on
 a
 regular
 basis.
 
 ESR
 has
 made
 a
 recent
 and
 very
 significant
 investment
 in
 infrastructure
 that
 will
 support
 this
 research,
 in
 particular
 the
 newly
 built
 and
 refurbished
 laborator ...
Pandemic Influenza and Pregnant Women
Pandemic Influenza and Pregnant Women

... pregnant women were compared with postpartum women (a group considered to be most similar to pregnant women demographically and with regard to their health) and were found to be significantly more likely to be hospitalized for a cardiopulmonary event during the influenza season (4). The risk for hos ...
VIRTUAL HIGH THROUGHPUT SCREENING FOR AVIAN
VIRTUAL HIGH THROUGHPUT SCREENING FOR AVIAN

... four drugs have been shown to effectively prevent serious influenza·related complications such as bacterial or viral pneumonia. In addition, reports proved that . in some cases the viruses were resistance to the drugs (Le et al., 2005, Gubareva, 2004, McKimm-Breschkin, 2000, Wang et al., 2007). Stud ...
Influenza is an acute disease characterized by cough, coryza, fever
Influenza is an acute disease characterized by cough, coryza, fever

... timing of these events is explained by the fact that influenza pandemics occur only when a new (or novel) influenza A virus emerges and spreads globally. By definition, most people have never been exposed to these viruses and therefore are susceptible to infection by them. By contrast, seasonal infl ...
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Oseltamivir



Oseltamivir INN /ɒsəlˈtæmɨvɪər/, marketed under the trade name Tamiflu, is an antiviral medication used to treat influenza A and influenza B (flu), and to prevent flu after exposure. The medication is taken orally.The Infectious Disease Society of America, the United States' Centers for Disease Control and Prevention (CDC), and the United Kingdom's National Institute for Health and Care Excellence recommend the use of oseltamavir for people who have complications or are at high risk for complications who present within 48 hours of first symptoms of infection. They recommend its use to prevent infection in at-risk people but not the general population. The CDC recommends that clinicians use their discretion to treat those at lower risk who present within 48 hours of first symptoms of infection. However, these recommendations are controversial as are criticisms of the recommendations. A Cochrane review concluded that oseltamivir does not reduce hospitalizations, and that there is no evidence of reduction in complications of influenza (such as pneumonia) because of a lack of diagnostic definitions, or reduction of the spread of the virus. Two meta-analyses have concluded that benefits in those who are otherwise healthy do not outweigh its risks. They also found little evidence regarding whether treatment changes the risk of hospitalization or death in high risk populations. However, another meta-analysis found that oseltamivir was effective for prevention of influenza at the individual and household levels.Side effects include psychiatric symptoms, increased rates of vomiting, and headaches. It is pregnancy category C in the United States and category B in Australia meaning that it has been taken by a small number of women without signs of problems and in animal studies it looks safe. Dose adjustment may be needed in those with kidney problems.It was the first orally administered neuraminidase inhibitor commercially developed. It was discovered and developed by US-based Gilead Sciences, which licensed the exclusive rights to Roche in 1996. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.
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