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video slide - Morgan Community College
video slide - Morgan Community College

... the Human Genome Project • An alternative approach to sequencing genomes starts with sequencing random DNA fragments • Computer programs then assemble overlapping short sequences into one continuous sequence ...
video slide
video slide

... the Human Genome Project • An alternative approach to sequencing genomes starts with sequencing random DNA fragments • Computer programs then assemble overlapping short sequences into one continuous sequence ...
Prevalence of BRCA1/2 Gene Mutation Carriage Rate among Local
Prevalence of BRCA1/2 Gene Mutation Carriage Rate among Local

... findings are consistent with the present work, suggesting to that either the 185delAG mutation is of low penetrance or, more likely, carriers of this mutation would develop cancer at an older age compared with other BRCA1 gene mutations. It is well accepted that mutation frequencies of the BRCA1 and ...
Slide 1
Slide 1

... yet there are 30 breakpoints for only 37 genes ...
Chapter 17
Chapter 17

... • Three properties of RNA enable it to function as an enzyme – It can form a three-dimensional structure because of its ability to base pair with itself – Some bases in RNA contain functional groups – RNA may hydrogen-bond with other nucleic acid molecules ...
zChap04_140901 - Online Open Genetics
zChap04_140901 - Online Open Genetics

... template from a homologous chromosome that itself contains a copy of a transposon, then the total number of transposons in the genome will increase. Besides greatly expanding the overall DNA content of genomes, TEs contribute to genome evolution in many other ways. As already mentioned, they may dis ...
File - Mr. Cramer
File - Mr. Cramer

Pursuing DNA Catalysts for Protein Modification
Pursuing DNA Catalysts for Protein Modification

... years,26 ∼105-fold greater than that for protein, highlighting the unexpected nature of this finding. The possibility of oxidative cleavage rather than hydrolysis of DNA was addressed by a key experiment with H218O. The 18O became incorporated into the DNA product, thereby providing firm evidence for ...
Tumor suppressor genes as negative growth regulators in
Tumor suppressor genes as negative growth regulators in

... cell types, some studies have failed to demonstrate an association between neurofibromin and microtubules in vivo (Golubic et al., 1992; Nordlund ef al., 1993). Another feature of the anatomy of NF1 is the presence of at least two alternatively spliced exons (exons 23a and 48a) which produce at leas ...
PAX6 mRNA Transcript Analysis in Various Ocular/Non
PAX6 mRNA Transcript Analysis in Various Ocular/Non

... attempt three samples of ocular tissues such as lens epithelium, normal WBC lymphocytes, and the HeLa RNA were subjected to amplify the PAX6 gene using 5’ paired domain primer. When the RT-PCR products were run on 2.5% agarose gel the lens epithelium showed two PAX6 mRNA transcripts (PAX6 and PAX6 5 ...
Genetic Basis of Coronary Atherosclerosis
Genetic Basis of Coronary Atherosclerosis

... hyperlipoproteinemis is in APOE gene, which is located on the long arm of chromosome 19. The phenotype is characterized by elevated levels of ß (beta)-very low-density lipoproteins (VLDL), eruptive xanthoma, premature CAD, and peripheral vascular disease. ApoE has three isoforms of ε (epsilon) 2, 3, ...
Seven
Seven

... without requiring learning dataset of already known genes. In this paper we studied cluster structure of several genomes in the space of codon usage. This allowed to interpret some of the results obtained in other studies and propose a simpler method, which is, nevertheless, fully functional. Result ...
SEARCH_16S: A new algorithm for identifying 16S
SEARCH_16S: A new algorithm for identifying 16S

... neither genes nor fragments, indicating that their small-subunit rRNA genes are missing and these assemblies are not in fact "complete". SEARCH_16S reported fragments in five assemblies which had high-identity BLAST hits (97% to 100%) covering only partial sequences in GG97, strongly suggesting asse ...
! Mendel`s Law of Independent Assortment
! Mendel`s Law of Independent Assortment

... The Punnett square does this for us because we can easily see that each of these is ¼ of the total number of squares. How do we get the phenotypic results? The sum rule of probability tells us that when the same event can occur in more than one way, we can add the results. Because 1, 2, and 3 all re ...
Snímek 1
Snímek 1

... • There is one the most commonly inherited allele which is known to cause up to 70% of all cystic fibrosis cases. This mutation is called the delta – F508 mutation • Δ F508 allele has 3 nucleotides deletion, which code for the amino acid phenylalanine (F) in the 508 position of the amino acid sequen ...
Antibiotics involved in Clostridium difficile
Antibiotics involved in Clostridium difficile

... genes, rrs (encoding the 16S rRNA subunit), gluD (encoding glutamate dehydrogenase) and gyrA (encoding DNA gyrase subunit A), were evaluated for the toxigenic 79-685 and the non-toxigenic ATCC 43603 strains, under the following conditions: high sodium concentration, iron depletion and a subinhibitor ...
11.7 Repressor binds cooperatively at each operator using a helix
11.7 Repressor binds cooperatively at each operator using a helix

... phage of the same type from infecting a cell. It results from the synthesis of phage repressor by the prophage genome. Induction refers to the ability of bacteria (or yeast) to synthesize certain enzymes only when their substrates are present; applied to gene expression, refers to switching on trans ...
epigenetika III
epigenetika III

... - many different sex-determining systems in plants and animals with separate sexes. ...
Regulation of gene expression by polyunsaturated fatty acids
Regulation of gene expression by polyunsaturated fatty acids

... lipids such as DAG, can increase cellular concentrations of second messengers such as cyclic AMP (cAMP), inositol triphosphate (IP3), and calcium (Ca) (7). These second messengers or their lipid precursors can all have effects on gene expression (8). Alternatively, free fatty acids and fatty acyl Co ...
Last update: 06/22/2015
Last update: 06/22/2015

... expect (E) value of 5 x 10-117. Alignments with smaller E-values are more statistically significant and are less likely to have arisen by chance. Specifically, the E-value denotes the number of times we expect to see an alignment with scores equal to or greater than S when we align random sequences ...
lac
lac

... lacZ lacY lacA Its own promoter and encodes a repressor DNA protein. Transcription It is not part of the operon mRNA ...
Last update: 06/22/2015 Page 1 of 7 Introduction to BLAST using
Last update: 06/22/2015 Page 1 of 7 Introduction to BLAST using

File - Down the Rabbit Hole
File - Down the Rabbit Hole

... The coloration of tortoiseshell cats is a visible manifestation of X inactivation. The black and orange alleles of fur color are on the X chromosome. For any given patch of fur the inactivation of an X chromosome that carries one gene results in the fur color of the other active gene. ...
dna
dna

... How DNA Controls the Workings of the Cell Below are two partial sequences of DNA bases (shown for only one strand of DNA) Sequence 1 is from a human and sequence 2 is from a cow. In both humans and cows, this sequence is part of a set of instructions for controlling a bodily function. In this case, ...
幻灯片 1
幻灯片 1

... mouse models have provided valuable clues to the implantation process with respect to specific growth factors, cytokines, lipid mediators, adhesion molecules, and transcription factors. • A staggering amount of information from microarray experiments is also being generated at a rapid pace. If prope ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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