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1. Describe the function of the plasma membrane
1. Describe the function of the plasma membrane

... chemical force (the ion’s concentration gradient) and the electrical force (membrane potential) on the ion’s movement across the cell membrane ...
Lecture 7 - Université d`Ottawa
Lecture 7 - Université d`Ottawa

... membrane – allow free diffusion of any molecule of the appropriate size and charge • Aquaporins (plant and animal ells) • allow water molecules to cross the membrane much more rapidly than they can diffuse through the phospholipid bilayer • impermeable to charged ion ...
Lipid peroxidation modifies the assembly of biological membranes
Lipid peroxidation modifies the assembly of biological membranes

... 2006). The unsaturated fatty acids give a high degree of conformational flexibility to the unsaturated hydrocarbon chains in the membranes because they occupy a small wedge-shaped space. This generally results in looser packing and a more fluid membrane. In contrast, saturated fatty acids confer rig ...
1.1-BIO-HOM-HomeostasisIntro.CellMembrane
1.1-BIO-HOM-HomeostasisIntro.CellMembrane

... • Within the two layers, proteins are found. • These proteins help molecules to cross through the membrane, and it’s also a way that the cell can communicate with its environment ...
C - ISpatula
C - ISpatula

... pancreas into the extracellular space. The insulin molecules are first packaged into intracellular vesicles, which then fuse with the plasma membrane to release the insulin outside the cell. ...
C - ISpatula
C - ISpatula

... pancreas into the extracellular space. The insulin molecules are first packaged into intracellular vesicles, which then fuse with the plasma membrane to release the insulin outside the cell. ...
Physiologic factors related to drug absorption
Physiologic factors related to drug absorption

... pancreas into the extracellular space. The insulin molecules are first packaged into intracellular vesicles, which then fuse with the plasma membrane to release the insulin outside the cell. ...
Structure of the Cell Membrane
Structure of the Cell Membrane

... • Fluid Mosaic Model• The fluid-mosaic model describes the plasma membrane of animal cells. • The plasma membrane that surrounds these cells has two layers (a bilayer) of phospholipids (fats with phosphorous attached), which at body temperature are like vegetable oil (fluid). • And the structure of ...
8.2 Cell Transport
8.2 Cell Transport

... releasing sodium to the outside of the membrane – while open to the outside, potassium ions bind to the carrier protein – when the pump returns to its original shape the potassium ions are released on the inside. – For every 3 sodium ions taken out there are 2 potassium ions taken in ...
Transport Through the Membrane
Transport Through the Membrane

... Cholesterols found in animal cell membranes. These keep the membrane fluid at lower temperatures. They also prevent some other molecules from passing through.  Protein and carbohydrate arrangements in the cell membrane that allow the cell to be “recognized” by other cells. (Pg 52, fig 2.24) ...
Chapter 11 Selected Solutions
Chapter 11 Selected Solutions

... in the freezing cold (definitely not Zoo Miami!). Their membrane fatty acids need to be highly unsaturated so the membrane does not freeze solid. The inside of the animal is at a warmer temperature which like ours required that the membranes be fluid at a higher temperture. Thus, the inner parts of ...
Cell Membrane - Campbell County Schools
Cell Membrane - Campbell County Schools

... – The phospholipids in the bilayer float together like beach-balls on water. The lipids are in constant motion, and can slide past each other, and other molecules, like proteins can move in between them. ...
Cubic Phase Lipids
Cubic Phase Lipids

... We try to understand the physical basis of lipid phases, because an understanding of this basis gives insight into the forces at play in lipid bilayers. A polar biomembranes lipid interaction with water allows for a variety of structures, or polymorphs, not normally found in cells. These include, li ...
chapter 5 - Doral Academy Preparatory
chapter 5 - Doral Academy Preparatory

... diffusion of specific particles through transport proteins found in the membrane a.Transport Proteins are specific – they “select” only certain molecules to cross the membrane b.Transports larger or charged molecules ...
Movement Through the Cell Membrane
Movement Through the Cell Membrane

... 14. Cells are almost always __________ to fresh water, meaning there will be a net movement of water ____ the cell. Describe two ways that cells keep from bursting in fresh ...
Chapter 7: Cells and Their Environment
Chapter 7: Cells and Their Environment

... Cell Membrane cont. 3. Forms non-polar interior zone (middle layer) - Polar molecules (glucose, amino acids [AA], ions, cell wastes) can’t pass through b/c repelled by non-polar tails *** Advantage: Forms good barrier! - Problem: If cell membranes were made only of lipids, most substances could not ...
Membranes and Transport - Bio-Guru
Membranes and Transport - Bio-Guru

... allow ions and polar molecules across – even small ions like H+, Na+ or OH- cannot cross membranes • For the same reason, it does allow nonpolar molecules like O2, CO2 (Diffusion and osmosis) • Large molecules whether polar or nonpolar cannot cross over (most sugars, proteins, amino acids, lipids, e ...
Topic guide 14.2: Biological cell membranes
Topic guide 14.2: Biological cell membranes

... membrane to separate the contents from the environment, some substances do need to get into and out of cells. Some molecules can diffuse directly across membranes (e.g. oxygen), whereas others move through specific channels or are transported across by proteins. Proteins embedded in the membranes ac ...
MB207_10 - MB207Jan2010
MB207_10 - MB207Jan2010

... → Long-chain fatty acids have higher transition temperatures than shorterchain fatty acids. Membranes enriched in long-chain fatty acids tends to be less fluid. → Membranes containing many unsaturated fatty acids tend to have lower transition temperatures and thus more fluid than membranes with many ...
Cell Transport Power point
Cell Transport Power point

... on hypertonic side of selectively permeable membrane a. Cells filled with salts, sugars, proteins and other molecules- always hypertonic to fresh water b. Osmotic pressure produces movement of water into cell that is surrounded by fresh water. ...
(nucleus, cytosol, organelles, membrane) and their basic functions
(nucleus, cytosol, organelles, membrane) and their basic functions

... II. functions of the cell membrane ...
NOTES 2 Membrane_Transport - MacWilliams Biology
NOTES 2 Membrane_Transport - MacWilliams Biology

... 1. Diffusion through protein channels a. channels move specific molecules across cell membrane facilitated = with help b. NO energy needed ...
chapter 7 diffusion
chapter 7 diffusion

... concentration gradient, independent of concentration gradients of other ...
Biological Membranes - University of Malta
Biological Membranes - University of Malta

... acids tails at the centre. Micelles are stable structures. ...
Chapter 8. Movement across the Membrane
Chapter 8. Movement across the Membrane

... concentration gradient, independent of concentration gradients of other ...
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Lipid bilayer



The lipid bilayer is a thin polar membrane made of two layers of lipid molecules. These membranes are flat sheets that form a continuous barrier around all cells. The cell membranes of almost all living organisms and many viruses are made of a lipid bilayer, as are the membranes surrounding the cell nucleus and other sub-cellular structures. The lipid bilayer is the barrier that keeps ions, proteins and other molecules where they are needed and prevents them from diffusing into areas where they should not be. Lipid bilayers are ideally suited to this role because, even though they are only a few nanometers in width, they are impermeable to most water-soluble (hydrophilic) molecules. Bilayers are particularly impermeable to ions, which allows cells to regulate salt concentrations and pH by transporting ions across their membranes using proteins called ion pumps.Biological bilayers are usually composed of amphiphilic phospholipids that have a hydrophilic phosphate head and a hydrophobic tail consisting of two fatty acid chains. Phospholipids with certain head groups can alter the surface chemistry of a bilayer and can, for example, serve as signals as well as ""anchors"" for other molecules in the membranes of cells. Just like the heads, the tails of lipids can also affect membrane properties, for instance by determining the phase of the bilayer. The bilayer can adopt a solid gel phase state at lower temperatures but undergo phase transition to a fluid state at higher temperatures, and the chemical properties of the lipids' tails influence at which temperature this happens. The packing of lipids within the bilayer also affects its mechanical properties, including its resistance to stretching and bending. Many of these properties have been studied with the use of artificial ""model"" bilayers produced in a lab. Vesicles made by model bilayers have also been used clinically to deliver drugs.Biological membranes typically include several types of molecules other than phospholipids. A particularly important example in animal cells is cholesterol, which helps strengthen the bilayer and decrease its permeability. Cholesterol also helps regulate the activity of certain integral membrane proteins. Integral membrane proteins function when incorporated into a lipid bilayer, and they are held tightly to lipid bilayer with the help of an annular lipid shell. Because bilayers define the boundaries of the cell and its compartments, these membrane proteins are involved in many intra- and inter-cellular signaling processes. Certain kinds of membrane proteins are involved in the process of fusing two bilayers together. This fusion allows the joining of two distinct structures as in the fertilization of an egg by sperm or the entry of a virus into a cell. Because lipid bilayers are quite fragile and invisible in a traditional microscope, they are a challenge to study. Experiments on bilayers often require advanced techniques like electron microscopy and atomic force microscopy.
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