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Arsanis and Adimab Enter Into License Agreement
Arsanis and Adimab Enter Into License Agreement

... neutralizers reported to date,” said Guy Van Meter, VP of Business Development at Adimab. “This new agreement expands an already successful relationship with Arsanis, under which Arsanis’ lead program ASN100 for S. aureus pneumonia, currently in a Phase 2 clinical study, was discovered.” About Respi ...


... Also, as of February 2, 2016, one case of locally acquired and sexually transmitted Zika virus infection was confirmed in a patient in Texas. Possible cases of sexual transmission have been reported before, and the virus has occasionally been isolated in the seminal fluid of sick patients. Zika viru ...
West Nile Virus
West Nile Virus

... *Patient was treated for bacterial and viral meningitis with acyclovir, ceftriaxone, ampicillin, and vancomycin. Blood and CSF cultures were negative. *The patient continued to have fever, rigors, and declining mental status. Additionally, the motor impairment progressed to involve the upper extremi ...
Arsanis and Adimab Enter Into License Agreement to Target
Arsanis and Adimab Enter Into License Agreement to Target

... reported to date," said Guy Van Meter, VP of Business Development at Adimab. "This new agreement expands an already successful relationship with Arsanis, under which Arsanis' lead program ASN100 for S. aureus pneumonia, currently in a Phase 2 clinical study, was discovered." About Respiratory Syncyt ...
Causes of proctocolitis
Causes of proctocolitis

... population. Transmission of ciprofloxacin-resistant S. sonnei, among MSM in Montreal, Québec, has been reported.29 Partner notification: The possible source of infection should be ascertained if possible, in the knowledge that many infected individuals are symptomless. In most instances, sexual part ...
2013 European guideline on the management of proctitis
2013 European guideline on the management of proctitis

... In some patients with symptoms and signs of a distal proctitis, a causative organism cannot be detected. These individuals are said to have non-specific proctitis. If no infectious cause can be found and the proctitis persists after empiric therapy, the patient should be referred to a gastrointestin ...
2013 European Guideline on the management of proctitis
2013 European Guideline on the management of proctitis

... can be made when there are symptoms and signs, and a definitive diagnosis when the results of laboratory tests are available. The symptoms of proctitis include anorectal itching, pain, cramps (tenesmus) and discharge in and around the anal canal. Asymptomatic proctitis occurs frequently and can only ...
Avoiding infections
Avoiding infections

... genital sores. HSV is an infectious disease and is transmitted by direct contact of secretions from an infected person to one who is not infected. Like CMV, once you have herpes it lays inactive in your body and can reactivate periodically. The most common example of this is cold sores that occur in ...
Practice No - Hampshire County Council
Practice No - Hampshire County Council

... This summarises the measures to be taken when a member of staff contracts, or is in contact with, an infectious/notifiable disease. It specifies any need to restrict the employee’s activities within their workplace - to the point of exclusion until free from infection, and supports infection control ...
Skin Wounds Classification
Skin Wounds Classification

... o Eruption of small vesicles and/or pustules that rupture to form honey-colored crusts o Combo of 2 bacteria that spread rapidly when athletes in close contact with one another o Responds rapidly to proper treatment oThorough cleansing of crusted area oApplication of topical antibacterial agent ...
Understanding PML and the JC Virus in Multiple Sclerosis : Dr
Understanding PML and the JC Virus in Multiple Sclerosis : Dr

... leaves your body, and later in life it may flare up again and cause a condition called shingles. Similarly, people who have been infected with herpes always have the virus lurking in their nervous systems. During times of stress it will become active and an outbreak of sores will occur, but unless a ...
Central nervous system infections
Central nervous system infections

... and encephalitis  Numerous arthropod-borne togaviruses can cause meningitis or encephalitis  sometimes cause outbreaks of infection  In different parts of the world, different mammals, birds or even reptiles act as reservoirs and there are a variety of arthropod (mosquito and tick) vectors.  Usu ...
Guidelines for Management of Skin and Soft Tissue Infection
Guidelines for Management of Skin and Soft Tissue Infection

... Necrotizing skin and soft tissue infections: Necrotizing skin and soft tissue infections are deeper infections that typically involve the fascial and/or muscle compartments, causing major tissue destruction and a high rate of mortality if not aggressively managed. They can extend from an initial ski ...
Ministry of Health and Seniors Department of Health Frequently
Ministry of Health and Seniors Department of Health Frequently

... minor such as pimples or boils, or serious such as blood infections or pneumonia.  Methicillin is an antibiotic commonly used to treat staph infections. Although methicillin is very effective in treating most staph infections, some staph bacteria have developed resistance to methicillin and can no ...
Skin and Soft-Tissue Infections
Skin and Soft-Tissue Infections

...  Very early cases may be treated with topical medications  More advanced forms may need intravenous antibiotics  Placing a warm wet cloth over the area  can help remove ulcer crusts  You may recommend  antiseptic soap or peroxide washes to speed recovery ...
Epidemiology and Prevention of Viral Hepatitis A to E:
Epidemiology and Prevention of Viral Hepatitis A to E:

... tolerated, most patients will respond favorably. However, tendency to relapse on cessation of treatment. Another problem is the rapid emergence of drug resistance. Adefovir – less likely to develop resistance than Lamivudine and may be used to treat Lamivudine resistance HBV. However more expensive ...
Lesson Virology. Morphology and structure of viruses. Methods of
Lesson Virology. Morphology and structure of viruses. Methods of

... E – are capable of coding for their own proteins 10. Each of the following statements concerning viral surface proteins is correct EXCEPT: (A)*They participate in active transport of nutrients across the viral envelope membrane (B) They elicit antibody that neutralizes infectivity of the virus (C) T ...
Epidemiology and Prevention of Viral Hepatitis A to E:
Epidemiology and Prevention of Viral Hepatitis A to E:

... tolerated, most patients will respond favorably. However, tendency to relapse on cessation of treatment. Another problem is the rapid emergence of drug resistance. Adefovir – less likely to develop resistance than Lamivudine and may be used to treat Lamivudine resistance HBV. However more expensive ...
Root cause analysis in surgical site infections (SSIs)
Root cause analysis in surgical site infections (SSIs)

... species (with the exception of tetanus endospores). Although fungi are widely present in the environment, they rarely cause SSIs. Infection at another site may increase the risk of spreading infection through the bloodstream. Immunocompromised patients (e.g., those with HIV/AIDS, those with chronic ...
Cross Infection in Dentistry
Cross Infection in Dentistry

... hepatitis viruses F and G are yet to be fully evaluated and remain as potential sources of crossinfection (6). Cross-infection from herpes type 1 has been described from saliva contamination and contact and from contaminated dental record cards. The herpetic withlow on the fingers of a dentist was q ...
Antiviral Research Rapid sequence-based diagnosis of viral infection
Antiviral Research Rapid sequence-based diagnosis of viral infection

... frequently fail with viruses characterized by high mutation rates and genetic variability. Although degenerate primers and probes can be designed to accommodate sequence divergence, this typically entails a compromise in sensitivity. An additional confounding factor, perhaps the most significant, is ...
Shingles - Woodlands Surgery
Shingles - Woodlands Surgery

... Most people have chickenpox at some stage (usually as a child). The virus does not completely go after you have chickenpox. Some virus particles remain inactive in the nerve roots next to your spinal cord. They do no harm there, and cause no symptoms. For reasons that are not clear, the virus may be ...
Document
Document

... Medical University / Department of microbiology ...
Infections in Diabetics
Infections in Diabetics

... • Certain infections in Diabetics require more Hospitalisation days than other Diabetic complications • In U.S.A. > 60% Major Amputations as complication of D.M. ...
Introduction to STI prevention and control
Introduction to STI prevention and control

... STIs are a public health concern not only because of their high prevalence worldwide, but also because of their potential to cause serious and permanent complications in infected people who are not treated in a timely and effective way (see Table 1.1). In addition, they are known to facilitate HIV t ...
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Herpes simplex



Herpes simplex (Greek: ἕρπης herpēs, ""creeping"" or ""latent"") is a viral disease caused by the herpes simplex virus. Infections are categorized based on the part of the body infected. Oral herpes involves the face or mouth. It may result in small blisters in groups often called cold sores or fever blisters or may just cause a sore throat. Genital herpes, often simply known as herpes, may have minimal symptoms or form blisters that break open and result in small ulcers. These typically heal over two to four weeks. Tingling or shooting pains may occur before the blisters appear. Herpes cycles between periods of active disease followed by periods without symptoms. The first episode is often more severe and may be associated with fever, muscle pains, swollen lymph nodes and headaches. Over time, episodes of active disease decrease in frequency and severity. Other disorders caused by herpes simplex include: herpetic whitlow when it involves the fingers, herpes of the eye, herpes infection of the brain, and neonatal herpes when it affects a newborn, among others.There are two types of herpes simplex virus, type 1 (HSV-1) and type 2 (HSV-2). HSV-1 more commonly causes oral infections while HSV-2 more commonly causes genital infections. They are transmitted by direct contact with body fluids or lesions of an infected individual. Transmission may still occur when symptoms are not present. Genital herpes is classified as a sexually transmitted infection. It may be spread to an infant during childbirth. After infection, the viruses are transported along sensory nerves to the nerve cell bodies, where they reside lifelong. Causes of recurrence may include: decreased immune function, stress, and sunlight exposure. Oral and genital herpes is usually diagnosed based on the presenting symptoms. The diagnosis may be confirmed by viral culture or detecting herpes DNA in fluid from blisters. Testing the blood for antibodies against the virus can confirm a previous infection but will be negative in new infections.The most effective method of avoiding genital infections is by avoiding vaginal, oral and anal sex. Condom use decreases the risk somewhat. Daily antiviral medication taken by someone who has the infection can also reduce spread. There is no available vaccine and once infected, there is no cure. Paracetamol (acetaminophen) and topical lidocaine may be used to help with the symptoms. Treatments with antiviral medication such as aciclovir or valaciclovir can lessen the severity of symptomatic episodes.Worldwide rates of either HSV-1 or HSV-2 are between 60% and 95% in adults. HSV-1 is usually acquired during childhood. Rates of both increase as people age. Rates of HSV-1 are between 70% and 80% in populations of low socioeconomic status and 40% to 60% in populations of improved socioeconomic status. An estimated 536 million people worldwide (16% of the population) were infected with HSV-2 as of 2003 with greater rates among women and those in the developing world. Most people with HSV-2 do not realize that they are infected.
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