Meiotic DSBs and the control of mammalian recombination
... from their relative affinities for their DNA-binding sites. To the extent this latter possibility is important it may well reflect the relative age of each allele. Boulton et al. [14] pointed out a number of years ago that because the chromatid on which the initiating DSB occurs is repaired using it ...
... from their relative affinities for their DNA-binding sites. To the extent this latter possibility is important it may well reflect the relative age of each allele. Boulton et al. [14] pointed out a number of years ago that because the chromatid on which the initiating DSB occurs is repaired using it ...
Assisted Conception
... IVF - Embryo transfer • Embryos transferred to uterus on 2nd or 3rd day after in vitro insemination • 4-8 cells embryos • 2-3 embryos transferred in 20 µl of culture fluid • Transabdominal US to see fluid placed in uterus • Cryopreserve excess embryos ...
... IVF - Embryo transfer • Embryos transferred to uterus on 2nd or 3rd day after in vitro insemination • 4-8 cells embryos • 2-3 embryos transferred in 20 µl of culture fluid • Transabdominal US to see fluid placed in uterus • Cryopreserve excess embryos ...
View PDF - CiteSeerX
... by mutation. Moreover, if gene duplication occurs in either of the pair genes, and if crossover between the pair of chromosomes takes place, the dominant and recessive genes may be placed in the same chromosome. Thus, a diploid has much more diversity and a higher possibility of acquiring a new gene ...
... by mutation. Moreover, if gene duplication occurs in either of the pair genes, and if crossover between the pair of chromosomes takes place, the dominant and recessive genes may be placed in the same chromosome. Thus, a diploid has much more diversity and a higher possibility of acquiring a new gene ...
Linkage disequilibrium mapping in trisomic populations: analytical approaches and an application to congenital heart defects in Down syndrome.
... and/or recombination patterns along the nondisjoined chromosome in the cases compared with controls may indicate increased levels of homozygosity in specific chromosome regions. Increased levels of homozygosity can also be examined in the regions flanking candidate genes. Statistical tests to identi ...
... and/or recombination patterns along the nondisjoined chromosome in the cases compared with controls may indicate increased levels of homozygosity in specific chromosome regions. Increased levels of homozygosity can also be examined in the regions flanking candidate genes. Statistical tests to identi ...
Does RAGE protect smokers from COPD? CORRESPONDENCE
... Does RAGE protect smokers from COPD? To the Editors: We read with interest the article by SMITH et al. [1], which showed a positive correlation between plasma soluble receptor for advanced glycation end-products (sRAGE) and forced expiratory volume in 1 s (FEV1) in patients with chronic obstructive ...
... Does RAGE protect smokers from COPD? To the Editors: We read with interest the article by SMITH et al. [1], which showed a positive correlation between plasma soluble receptor for advanced glycation end-products (sRAGE) and forced expiratory volume in 1 s (FEV1) in patients with chronic obstructive ...
Genetic Testing for Hereditary Breast and/or Ovarian Cancer
... PTEN is the only gene that causes PTEN Hamartoma Tumor Syndrome (PHTS), which is diagnosed by a germline mutation in the gene. The lifetime risk of developing breast cancer is up to 85%, with an average age of diagnosis between 38 and 46 years, with 50% penetrance by 50 years of age.[5] Annual breas ...
... PTEN is the only gene that causes PTEN Hamartoma Tumor Syndrome (PHTS), which is diagnosed by a germline mutation in the gene. The lifetime risk of developing breast cancer is up to 85%, with an average age of diagnosis between 38 and 46 years, with 50% penetrance by 50 years of age.[5] Annual breas ...
Computer simulations: tools for population and evolutionary genetics
... Genome to simulate the genealogy of a population in which some individuals had rare variants associated with a disease. This study shows that weak signals detected for common variants could come from the effect of rare ones that could have large effects but that remain undetected by GWASs. Simulatio ...
... Genome to simulate the genealogy of a population in which some individuals had rare variants associated with a disease. This study shows that weak signals detected for common variants could come from the effect of rare ones that could have large effects but that remain undetected by GWASs. Simulatio ...
Unit 10.1.4 - Measuring Genetic Variation using Molecular Markers
... heteromers can complicate the banding patterns considerably. This is shown in the next slide. In view of these complexities and the importance of correctly interpreting banding patterns, genetic analysis is desirable and often necessary. For instance, in self-incompatible plants, this can be achieve ...
... heteromers can complicate the banding patterns considerably. This is shown in the next slide. In view of these complexities and the importance of correctly interpreting banding patterns, genetic analysis is desirable and often necessary. For instance, in self-incompatible plants, this can be achieve ...
Using Mice to Dissect Genetic Factors in Atherosclerosis
... precision to detect QTLs, mainly owing to the small number of available strains in each set. Recently, Williams et al4 published a dense map for all RI sets that share C57BL/6J as a parental strain, which might provide a tool for RI mapping of some complex traits in the future. In recent years, inve ...
... precision to detect QTLs, mainly owing to the small number of available strains in each set. Recently, Williams et al4 published a dense map for all RI sets that share C57BL/6J as a parental strain, which might provide a tool for RI mapping of some complex traits in the future. In recent years, inve ...
- Wiley Online Library
... signals that bind to and modify the activity of intracellular effector molecules (Shi et al., 2005). Very recently, Fontaine et al. (2010) succeeded in identifying the S. thermophilus competence pheromone as well as its intracellular target protein. The novel oligopeptide pheromone, ComS, turned out ...
... signals that bind to and modify the activity of intracellular effector molecules (Shi et al., 2005). Very recently, Fontaine et al. (2010) succeeded in identifying the S. thermophilus competence pheromone as well as its intracellular target protein. The novel oligopeptide pheromone, ComS, turned out ...
Supplementary Table S1
... compared to low levels […]. High Levels […] are also predictive of poor response to platinumbased chemotherapy.” ( “Category 2A: Based on lower-level evidence, there is uniform NCCN consensus that the intervention is appropriate”) ASCO: “The studies suggest that low levels of these markers may be pr ...
... compared to low levels […]. High Levels […] are also predictive of poor response to platinumbased chemotherapy.” ( “Category 2A: Based on lower-level evidence, there is uniform NCCN consensus that the intervention is appropriate”) ASCO: “The studies suggest that low levels of these markers may be pr ...
An Efficient Approach to Genetic Algorithm for Task
... completion time of all cloudlets in the list. To formulate the problem we considered cloudlets ( C1, C2,C3…..Cn) run on processors (P1, P2, P3…..Pn). . Our objective is to minimize Make-span. The speed of processors is expressed in MIPS (Million instructions per second) and length of job can be expr ...
... completion time of all cloudlets in the list. To formulate the problem we considered cloudlets ( C1, C2,C3…..Cn) run on processors (P1, P2, P3…..Pn). . Our objective is to minimize Make-span. The speed of processors is expressed in MIPS (Million instructions per second) and length of job can be expr ...
A Generic Parallel Genetic Algorithm
... An operator to avoid permanent loss of (and to introduce new) diversity within the solutions – mutation. ...
... An operator to avoid permanent loss of (and to introduce new) diversity within the solutions – mutation. ...
Analysis of Biological Networks: Genetic Interaction Networks
... Figure 4: Source: [4]. Connections between gene functions based on synthetic genetic interaction. Colored cells in this matrix represent pairs of GO attributes that are associated with genetic interactions more than would be expected by chance (p < 0.05). 2. Two GO annotations A and B are considere ...
... Figure 4: Source: [4]. Connections between gene functions based on synthetic genetic interaction. Colored cells in this matrix represent pairs of GO attributes that are associated with genetic interactions more than would be expected by chance (p < 0.05). 2. Two GO annotations A and B are considere ...
Genes, Environment and Sport Performance
... considerable advancement in the methods of examination, it is unlikely they will be resolved soon. This is not to say that understanding of genetic and environmental influence has not advanced. It certainly has; moreover, these advances have obvious importance for understanding the development of ex ...
... considerable advancement in the methods of examination, it is unlikely they will be resolved soon. This is not to say that understanding of genetic and environmental influence has not advanced. It certainly has; moreover, these advances have obvious importance for understanding the development of ex ...
Family History of Bowel Cancer
... In your family the pattern of cancers doesn’t suggest a known inherited form of bowel cancer. However, your family history means relatives do have a slightly higher risk of developing bowel cancer than other people their age. It is still much more likely that individuals in the family won’t develop ...
... In your family the pattern of cancers doesn’t suggest a known inherited form of bowel cancer. However, your family history means relatives do have a slightly higher risk of developing bowel cancer than other people their age. It is still much more likely that individuals in the family won’t develop ...
is merriam`s elk really extinct?
... American elk that inhabited mountain ranges in the southwestern U.S., primarily in Arizona and New Mexico until it was presumed extinct by 1906. Starting in 1913, elk from Yellowstone National Park were translocated to Arizona and the species became reestablished in the state. Arizona is known for p ...
... American elk that inhabited mountain ranges in the southwestern U.S., primarily in Arizona and New Mexico until it was presumed extinct by 1906. Starting in 1913, elk from Yellowstone National Park were translocated to Arizona and the species became reestablished in the state. Arizona is known for p ...
The Neurobiology of ADHD, Understanding the Brain
... The most general finding is hypoactivation in the ventralstriatal system during tasks that measure differential response to rewards between ADHD and Control groups ...
... The most general finding is hypoactivation in the ventralstriatal system during tasks that measure differential response to rewards between ADHD and Control groups ...
The post myocardial infarction exercise test: still
... would not be possible today — indeed, such a ‘retrospective’ approach represents one answer to the problem of ‘work-up bias’ (data can only be gathered within the bounds of contemporary clinical practice). Perhaps the most consistent finding in the postmyocardial infarction exercise test studies tha ...
... would not be possible today — indeed, such a ‘retrospective’ approach represents one answer to the problem of ‘work-up bias’ (data can only be gathered within the bounds of contemporary clinical practice). Perhaps the most consistent finding in the postmyocardial infarction exercise test studies tha ...
Genetic Testing in Male Infertility
... fluorochromes to the complementary DNA sequences for the region of interest. The fluorochromes are then visualized under the fluorescent microscope. Fluorochrome probes for centromere, telomere and whole chromosome (chromosome painting) are also available. Unlike conventional cytogenetic analysis, F ...
... fluorochromes to the complementary DNA sequences for the region of interest. The fluorochromes are then visualized under the fluorescent microscope. Fluorochrome probes for centromere, telomere and whole chromosome (chromosome painting) are also available. Unlike conventional cytogenetic analysis, F ...
Y-Chromosome Marker S28 / U152 Haplogroup
... for this haplogroup, which includes links to many items of interest to those who fall into the R-U152 haplogroup. More recently Richard Rocca has set up a website devoted to the study of this haplogroup. Can the relationship between individuals who are identified as U152 positive be seen in a graphi ...
... for this haplogroup, which includes links to many items of interest to those who fall into the R-U152 haplogroup. More recently Richard Rocca has set up a website devoted to the study of this haplogroup. Can the relationship between individuals who are identified as U152 positive be seen in a graphi ...
Cat Health Network Feline SNP Chip Studies Lay Language
... the Mediterranean, and North Africa. Several subspecies of wildcats occupy these areas, the African wildcat (Felis silvestris libyca) is the subspecies considered to be most influential in cat domestication. However, because of the extensive habitat overlaps, populations of European wildcat (Felis s ...
... the Mediterranean, and North Africa. Several subspecies of wildcats occupy these areas, the African wildcat (Felis silvestris libyca) is the subspecies considered to be most influential in cat domestication. However, because of the extensive habitat overlaps, populations of European wildcat (Felis s ...
