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large intestine
large intestine

... colonic smooth muscle cells. • They help to mix the contents of colon and expose contents to mucosa to facilitate absorption. ...
UNDERSTANDING THE INFLAMMATORY RESPONSE By Dr. John
UNDERSTANDING THE INFLAMMATORY RESPONSE By Dr. John

... organisms, harmful toxins, and physical injury. It is a protective and restorative process that helps keep us healthy - most of the time. Unfortunately, when inflammation becomes excessive or uncontrolled, we begin to see chronic inflammation which can lead to poor physical health. Learn more about ...
Ampignious Choroiditis – Dr. Henry Kaplan
Ampignious Choroiditis – Dr. Henry Kaplan

... – Mild vitritis (35%) – Prolong relapsing course: 6 months to 5 years – Different complications • Present: Subretinal fibrosis and ERM • Absent: optic disc swelling, CNV, SRF ...
Corticosteroids: a miracle drug that must be handled with care
Corticosteroids: a miracle drug that must be handled with care

... So an over­the­counter steroid like hydrocortisone, applied to small areas of skin to relieve poison ivy or eczema, is unlikely to have any untoward effects.  But when injected repeatedly into a muscle or joint, corticosteroids can cause weakening and degenerative changes that limit their usefulness ...
Modulating the Gut Microbiome: The Role of
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Oral ulcerations
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Digestive Function of the Large Intestine
Digestive Function of the Large Intestine

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ID Amebiasis
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Can nicotine use alleviate symptoms of psoriasis?
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... soriasis is a common chronic skin disorder with an estimated prevalence in the United States of 2.5% in white individuals and 1.3% in African Americans.1 Although psoriasis can manifest at any age, there seem to be 2 peaks in onset: one between the ages of 20 and 30 years, and another between the ag ...
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Graves` Disease - American Thyroid Association
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Rheumatoid Arthritis by Dr Sarma
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... MTX is given 10 to 30 mg orally, IM, or SC per week It is DHF reductase inhibitor – Supplemental folic acid The clinical improvement takes one to two months Nausea, diarrhea; mouth ulcers; rash, alopecia; Abnormal LFT Rare: low WBC & platelets; pneumonitis; sepsis; liver disease; EBV related lymphom ...
Microscopic Polyangitis
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Common Misconceptions About Pilonidal Disease
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International Journal of Antimicrobial Agents Toxin-binding
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... Clostridium difficile is a toxin-mediated disease in which two main toxins, A and B, are responsible for the clinical picture [11]. For a long time toxin A was thought to be the key component in triggering the disease pathogenesis, but toxin B now appears to play an equally important role. They both ...
1. Outline the steps in performing an abdominal examination. 2
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... 2. assessing the umbilicus – is it inflamed, clean? 3. assessing skin turgor - is the patient dehydrated? 4. looking for movement associated with peristalsis b. Auscultation i. Primary purpose is to listen for bowel sounds. Also is used to assess vascular sounds ii. Procedure: 1. Perform prior to pa ...
Endoscopic Balloon Dilatation of NSAID
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... strictures mainly in the cecum and ascending colon and rarely in other colonic parts remains obscure. NSAIDs exert their effects on gut mucosa either locally or systemically. Local damage is a more likely explanation and one can assume that the intra-luminal NSAIDs concentration is an important fact ...
Ocular Inflammatory Diseases - Sight Loss and Vision Priority
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... Biomarkers: Molecules found in blood, other body fluids or tissues that can indicate normal or abnormal processes, conditions and diseases as well as indicate response to treatment. Calcineurin inhibitors: A group of drugs that are used as immunosuppressants. Environment: Outside influences on heal ...
Psoriatic Arthritis and the Complications of Systemic Inflammation
Psoriatic Arthritis and the Complications of Systemic Inflammation

... In the US, about 7.5 million people have psoriasis, a chronic immunemediated, inflammatory disease. As with many chronic conditions, there is often a delay in diagnosis. Patients may be slow to seek treatment, and providers often overlook the severity and true burden of the disease, especially in mi ...
QuickTime™ and a TIFF (Uncompressed) decompressor QuickTime
QuickTime™ and a TIFF (Uncompressed) decompressor QuickTime

... Prediction of clinical course, response to therapy, and disease outcome ...
Endoscopic Balloon Dilatation of NSAID
Endoscopic Balloon Dilatation of NSAID

... the descending colon over the stenosis, transverse, ascending and up to the cecum looked normal. The patient noted resolution of abdominal pain and constipation. NSAIDs were discontinued and one year later the patient is free of symptoms reporting use of non-NSAIDs analgesic agents only. ...
Large Intestine/Barium Enema
Large Intestine/Barium Enema

... radiology department. Which procedure should be performed on this patient to rule out this condition? (5pts) ...
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Ulcerative colitis



Ulcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD) that causes inflammation and ulcers in the colon. The disease is a type of colitis, which is a group of diseases that cause inflammation of the colon, the largest section of the large intestine, either in segments or completely. The main symptom of active disease is usually constant diarrhea mixed with blood, of gradual onset. IBD (Crohn's disease (CD) and ulcerative colitis (UC)) is often confused with irritable bowel syndrome (IBS).Ulcerative colitis has much in common with Crohn's disease, another form of IBD, but what sets it apart from Crohn's disease is that ulcerative colitis, as its name suggests, only affects the colon and rectum, leaving the rest of the gastrointestinal tract unscathed, while Crohn's disease can affect the whole GI tract from mouth to anus. Also, surgical removal of the colon and rectum cures ulcerative colitis, which actually means the disease does not recur after surgery, unlike Crohn's disease, which has a tendency to recur after surgery to remove the abnormal part of the bowel and connect the healthy ends. Ulcerative colitis is an intermittent disease, with periods of exacerbated symptoms, and periods that are relatively symptom-free. Although the symptoms of ulcerative colitis can sometimes diminish on their own, the disease usually requires treatment to go into remission. Ulcerative colitis has an incidence of 1 to 20 cases per 100,000 individuals per year, and a prevalence of 8 to 246 per 100,000 individuals.The disease is more prevalent in northern countries of the world, as well as in northern areas of individual countries or other regions. Rates tend to be higher in more affluent countries, which may indicate the increased prevalence is due to increased rates of diagnosis. It may also indicate that an industrial or Western diet and lifestyle increases the prevalence of this disease, including symptoms which may or may not be related to ulcerative colitis. Although UC has no known cause, there is a presumed genetic component to susceptibility. The disease may be triggered in a susceptible person by environmental factors. Dietary modification may reduce the discomfort of a person with the disease.Like Crohn's disease, ulcerative colitis is both classed as and managed as an autoimmune disease. Management is with anti-inflammatory drugs, immunosuppression, and biological therapy targeting specific components of the immune response. Colectomy (partial or total removal of the large bowel through surgery) is occasionally necessary if the disease is severe, does not respond to treatment, or if significant complications develop. A total proctocolectomy (removal of the entirety of the large bowel and rectum) can cure ulcerative colitis as the disease only affects the large bowel and rectum and does not recur after removal of the latter. While extra-intestinal symptoms will remain, complications may develop.
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