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3-bromopiruvato. Em várias linhagens de células cancerosas o alvo
3-bromopiruvato. Em várias linhagens de células cancerosas o alvo

... BACKGROUND: The pyruvic acid analog 3-bromopyruvate (3BrPA) is an alkylating agent known to induce cancer cell death by blocking glycolysis. The anti-glycolytic effect of 3BrPA is considered to be the inactivation of glycolytic enzymes. Yet, there is a lack of experimental documentation on the direc ...
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... Possible solution #2: Connect many cells sequentially • The downside of this system: • There is a delay at every electrical junction between the cells. • The distance from motor cortex in the brain to the toe muscle = 2meters. • 2meters / 20micrometers cells = 100,000 cells • Assume that inside a c ...
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... Unit and diversity of cells Cells differ from one another in size, form and chemistry. These variations make it possible for different cells to perform different functions. Some cells are specialised “factories” for the production of certain substances such as hormones, starches, fat, latex or pigme ...
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characteristics of prokaryotic and eukaryotic cells

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Functional Anatomy of Prokaryotic and Eukaryotic Cells
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capitulo primero

... oxygenic photosynthesis in turn required adaptation of metal transport and homeostasis since metalcatalyzed generation of reactive oxygen species (ROS) causes oxidative damage. This is most acute in chloroplasts, where radicals and transition metals are side by side and ROS-production is a usual fea ...
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Signal transduction



Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.
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