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Text S1.

... BC-3 and BCBL-1 cells were washed twice in PBS, and fixed in 4% paraformaldehyde (PFA) for 15 minutes at room temperature. Cells were washed twice with 3% FCS in PBS and permeabilized with 0.5% NP-40 (Sigma; St. Louis, MO) for 5 minutes at room temperature. Cells were applied onto glass slides and a ...
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Cell Notes PPT - Winston Knoll Collegiate

... • Cells are the basic units of structure and function of living things • All cells are produced from other cells ...
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Signal transduction



Signal transduction occurs when an extracellular signaling molecule activates a specific receptor located on the cell surface or inside the cell. In turn, this receptor triggers a biochemical chain of events inside the cell, creating a response. Depending on the cell, the response alters the cell's metabolism, shape, gene expression, or ability to divide. The signal can be amplified at any step. Thus, one signaling molecule can cause many responses.
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