The Evolution of the Myofibroblast Concept: a Key Cell for
... by fibroblastic cells, of transforming growth factorβ1 (TGF-β1), the most accepted stimulator of myofibroblastic differentiation 5. The action of TGF-β1 depends on the local presence of the cellular fibronectin splice variant ED-A 6. Thus, myofibroblast differentiation is regulated by both a cell pr ...
... by fibroblastic cells, of transforming growth factorβ1 (TGF-β1), the most accepted stimulator of myofibroblastic differentiation 5. The action of TGF-β1 depends on the local presence of the cellular fibronectin splice variant ED-A 6. Thus, myofibroblast differentiation is regulated by both a cell pr ...
Peroxiredoxin-controlled G-CSF signalling at the endoplasmic
... phagocytes the Nox system mainly serves to produce high levels of H2O2 for the so-called oxidative burst, a major weapon in host defence against bacteria. In non-phagocytic cells, H2O2 has long been considered as an unwanted by-product of cell metabolism, potentially hazardous because of the damagin ...
... phagocytes the Nox system mainly serves to produce high levels of H2O2 for the so-called oxidative burst, a major weapon in host defence against bacteria. In non-phagocytic cells, H2O2 has long been considered as an unwanted by-product of cell metabolism, potentially hazardous because of the damagin ...
pseudopodium induction by the action of quaternary ammonium
... the compound may be obtained. Thus, the C12quat and C14quat salts were able to induce new pseudopodia from retreating pseudopodia or from approximately twothirds of the cell length from the advancing front. The C16quat and succinyl dicholine were able to induce new pseudopodia from half-way along th ...
... the compound may be obtained. Thus, the C12quat and C14quat salts were able to induce new pseudopodia from retreating pseudopodia or from approximately twothirds of the cell length from the advancing front. The C16quat and succinyl dicholine were able to induce new pseudopodia from half-way along th ...
The Cell Membrane
... All cells are surrounded by a cell membrane (also called the plasma membrane). This is a biological membrane or biomembrane consisting of a double layer of lipids in which proteins are located. The cell membrane keeps the components of the cell isolated from the external environment. It also serves ...
... All cells are surrounded by a cell membrane (also called the plasma membrane). This is a biological membrane or biomembrane consisting of a double layer of lipids in which proteins are located. The cell membrane keeps the components of the cell isolated from the external environment. It also serves ...
Cell Cycle, Mitosis and Cytokinesis
... extract an unidentified substance that, when injected into healthy chickens, caused cancer. – not bacteria because it was carefully filtered, ...
... extract an unidentified substance that, when injected into healthy chickens, caused cancer. – not bacteria because it was carefully filtered, ...
oncogene
... But how can we find oncogenes that are not viral oncogenes? Add DNA from carcinogen-treated cell? ...
... But how can we find oncogenes that are not viral oncogenes? Add DNA from carcinogen-treated cell? ...
Research Article Immunohistochemical and
... and immune cells. Results. Immunohistochemical results revealed that all stained cells were located in the cambium layer and that most cells were positive for vimentin. The majority of cells consisted of stromal stem cells and osteoblastic precursor cells. The density increased towards the deeper la ...
... and immune cells. Results. Immunohistochemical results revealed that all stained cells were located in the cambium layer and that most cells were positive for vimentin. The majority of cells consisted of stromal stem cells and osteoblastic precursor cells. The density increased towards the deeper la ...
Figure 4 – Albendazole induced cell cycle arrest at G2/M phase.
... • Growth inhibition was associated with cell death in the sensitive lines, likely involving apoptosis based on observed PARP cleavage. • Flow cytometry analysis demonstrated that albendazole treatment arrested HNSCC cells in the G2/M phase, potentially due to the drugs ability to inhibit tubulin pol ...
... • Growth inhibition was associated with cell death in the sensitive lines, likely involving apoptosis based on observed PARP cleavage. • Flow cytometry analysis demonstrated that albendazole treatment arrested HNSCC cells in the G2/M phase, potentially due to the drugs ability to inhibit tubulin pol ...
nonsurgical management skin cancers
... 500 lesions of BD in 2 patients with 1.5-2 mg/kg of HpD and a 628-nm wavelength pulsed gold vapor laser (25 J/cm2). A complete response rate of 100% with less than 10% of the lesions requiring a second treatment was achieved. A similar result was achieved with 1 mg/kg porfimer sodium and an argon dy ...
... 500 lesions of BD in 2 patients with 1.5-2 mg/kg of HpD and a 628-nm wavelength pulsed gold vapor laser (25 J/cm2). A complete response rate of 100% with less than 10% of the lesions requiring a second treatment was achieved. A similar result was achieved with 1 mg/kg porfimer sodium and an argon dy ...
Ultrastructural Aspects of Human and Canine Diabetic
... nature of the initial dilatation of capillaries to form microaneurysms, or the unusual permeability of these areas. Death of pericytes may play a role in development of diabetic retinopathy. The reason for the death of these cells is unknown but may be related to the metabolic derangements of diabet ...
... nature of the initial dilatation of capillaries to form microaneurysms, or the unusual permeability of these areas. Death of pericytes may play a role in development of diabetic retinopathy. The reason for the death of these cells is unknown but may be related to the metabolic derangements of diabet ...
Characterization of a Human Colorectal Carcinoma Cell Line with
... cell division. Core regulators are the cyclins and cyclin-dependent kinases (cdks) (Musunuru and Hinds, 1997). Because the cell cycle is deregulated in many cancers, it has been targeted for the development of new anticancer agents (Fry and Garrett, 2000), particularly with respect to inhibitors of ...
... cell division. Core regulators are the cyclins and cyclin-dependent kinases (cdks) (Musunuru and Hinds, 1997). Because the cell cycle is deregulated in many cancers, it has been targeted for the development of new anticancer agents (Fry and Garrett, 2000), particularly with respect to inhibitors of ...
Protistology A study of the soil flagellate Phalansterium solitarium
... protozologists have had no time to search for them. Thus, Phalansterium solitarium is one of the very few flagellates with a clear light microscopical identity originally described from soil material (Foissner, 1991) that has been known for a long period. This suggests that the reason it has never b ...
... protozologists have had no time to search for them. Thus, Phalansterium solitarium is one of the very few flagellates with a clear light microscopical identity originally described from soil material (Foissner, 1991) that has been known for a long period. This suggests that the reason it has never b ...
Chapter 32
... 2. Many angiosperm trees abscise in the fall in preparation for winter or dry period 3. Abscission is initiated by plant hormones, particularly ethylene a) Chlorophylls break down, and readily available nutrients are transported from the leaves to the woody tissues (see carotenoids), and red anthocy ...
... 2. Many angiosperm trees abscise in the fall in preparation for winter or dry period 3. Abscission is initiated by plant hormones, particularly ethylene a) Chlorophylls break down, and readily available nutrients are transported from the leaves to the woody tissues (see carotenoids), and red anthocy ...
paramecium tetraurelia.
... nucleus is derived from micronucIei and gives rise to two new macronuclei, which are readily identified as different from other nuclear structures found; hence, if micronuclei are absent or nonfunctional, neither a fertilization nucleus nor the two distinctive new macronuclei can be formed and nucle ...
... nucleus is derived from micronucIei and gives rise to two new macronuclei, which are readily identified as different from other nuclear structures found; hence, if micronuclei are absent or nonfunctional, neither a fertilization nucleus nor the two distinctive new macronuclei can be formed and nucle ...
YEAR 11 BIOLOGY - Matrix Education
... stated that life spontaneously originates from non-living matter and NOT from another living cell, as known nowadays. ...
... stated that life spontaneously originates from non-living matter and NOT from another living cell, as known nowadays. ...
Chapter 5 Cancer: DNA Synthesis, Mitosis, and Meiosis
... the cell cycle to bypass or ignore checkpoints Keep dividing regardless of mutations and problems More and more mutations occur More and more cell divisions occur Bigger and nastier tumors occur Copyright © 2007 Pearson Prentice Hall, Inc. ...
... the cell cycle to bypass or ignore checkpoints Keep dividing regardless of mutations and problems More and more mutations occur More and more cell divisions occur Bigger and nastier tumors occur Copyright © 2007 Pearson Prentice Hall, Inc. ...
EphA2 (D4A2) XP® Rabbit mAb
... EphA2 is overexpressed in various tumor cells, and it has been suggested that EphA2 may promote malignancy. However, several studies demonstrate that EphA2 plays an important role in tumor suppression (8). The role of EphA2 in tumor development may depend upon regulation of its tyrosine kinase activ ...
... EphA2 is overexpressed in various tumor cells, and it has been suggested that EphA2 may promote malignancy. However, several studies demonstrate that EphA2 plays an important role in tumor suppression (8). The role of EphA2 in tumor development may depend upon regulation of its tyrosine kinase activ ...
OMB No. 0925-0046 (Approved Through 5/31/2016)
... Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors. Clinical Cancer Research, 19:1512-24, 2013. PMCID:PMC3602220 (62 citations) c. The clinical efficacy of anti-angiogenic agents such as the Vegf inhibitor, bevicuzumab have been relatively disappoint ...
... Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors. Clinical Cancer Research, 19:1512-24, 2013. PMCID:PMC3602220 (62 citations) c. The clinical efficacy of anti-angiogenic agents such as the Vegf inhibitor, bevicuzumab have been relatively disappoint ...
Cell encapsulation
Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.