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Direct Nuclear Transport of Aptamer-RNA Chimeras to
Direct Nuclear Transport of Aptamer-RNA Chimeras to

... of therapeutics rivaling antibodies in binding specificity and affinity at a fraction of their size and with minimal immunogenic activity. Furthermore, aptamer-chimeras (ACs) are developing into potent cell-type specific vectors for delivering RNA or DNA cargoes. However, current methods have limite ...
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Cell encapsulation



Cell microencapsulation technology involves immobilization of the cells within a polymeric semi-permeable membrane that permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells regarding them as foreign invaders.The main motive of cell encapsulation technology is to overcome the existing problem of graft rejection in tissue engineering applications and thus reduce the need for long-term use of immunosuppressive drugs after an organ transplant to control side effects.
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