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CHAPTER 2 Prokaryotic and Eukaryotic Cells
CHAPTER 2 Prokaryotic and Eukaryotic Cells

... cytoplasm: Entire contents of the cell inside the plasma membrane, excluding the nucleus. deoxyribonucleic acid (DNA): Nucleic acid that is the genetic material of all organisms. endoplasmic reticulum: Organelle that is the site of lipid synthesis and protein modification. eukaryote: Organism with c ...
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... 3. Rudolf, E.; Rudolf, K.; Cervinka, M. Selenium activates p53 and p38 pathways and induces caspase-independent cell death in cervical cancer cells . Cell Biology and Toxicology. 2008, vol. 24, no. 2, s. 123-141 4. Rudolf, E.; Cervinka, M. The role of intracellular zinc in chromium(VI)-induced oxida ...
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... − a nucleus which controls the activities of the cell − cytoplasm in which most of the chemical reactions take place − a cell membrane which controls the passage of substances in and out of the cell − mitochondria, which is where most energy is released inrespiration − ribosomes, which is where prot ...
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Cellular differentiation



In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.
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