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The Endomembrane System
The Endomembrane System

... to proteins in ER. Exocytosis, or stay as part of cell (e.g. lysosomes). ...
Which one Will Dry out Last?
Which one Will Dry out Last?

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Eukaryotic Origins
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Cell adhesion receptors and the control of cell cycle Cell adhesion
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... sponges to mammals. They are composed of two subunits, α and β, and each αβ combination has its own binding specificity and signaling properties. Most integrins recognize several ECM proteins. Conversely, individual matrix proteins, such as fibronectin, laminins, collagens, and vitronectin, bind to ...
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DNA methylation analysis of murine hematopoietic side population
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vonandrian_blog_review_120207_jws
vonandrian_blog_review_120207_jws

... Mature lymphocytes that circulate in blood migrate into organs and subsequently drain into lymph for immunosurveillance. To investigate whether circulating HSCs themselves follow this path, von Andrian’s group initially identified a HSC pool in thoracic duct lymph using both immunotyping and serial ...
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The Four Stages of Mitosis
The Four Stages of Mitosis

... pair suddenly part, making each chromatid a chromosome As kinetochore microtubules shorten the chromosomes are pulled to opposite ends of the cell The cell elongates as the nonkinetochore microtubules lengthen As anaphase ends the two ends of the cell have equivalent and complete collections of chro ...
AN OPTICAL-INDUCED PLATFORM FOR MULTIPLE GENES
AN OPTICAL-INDUCED PLATFORM FOR MULTIPLE GENES

... Figure 3. The transfection efficiency at different illumination time when 13 Vpp and 100 kHz were applied. Note that the case “E” is the result obtained from a traditional electroporator. The capability of the developed platform for multiple plasmid transfection was also explored. Figure 4 shows th ...
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Cellular differentiation



In developmental biology, cellular differentiation isa cell changes from one cell type to another. Most commonly this is a less specialized type becoming a more specialized type, such as during cell growth. Differentiation occurs numerous times during the development of a multicellular organism as it changes from a simple zygote to a complex system of tissues and cell types. Differentiation continues in adulthood as adult stem cells divide and create fully differentiated daughter cells during tissue repair and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape, membrane potential, metabolic activity, and responsiveness to signals. These changes are largely due to highly controlled modifications in gene expression and are the study of epigenetics. With a few exceptions, cellular differentiation almost never involves a change in the DNA sequence itself. Thus, different cells can have very different physical characteristics despite having the same genome.A cell that can differentiate into all cell types of the adult organism is known as pluripotent. Such cells are called embryonic stem cells in animals and meristematic cells in higher plants. A cell that can differentiate into all cell types, including the placental tissue, is known as totipotent. In mammals, only the zygote and subsequent blastomeres are totipotent, while in plants many differentiated cells can become totipotent with simple laboratory techniques. In cytopathology, the level of cellular differentiation is used as a measure of cancer progression. ""Grade"" is a marker of how differentiated a cell in a tumor is.
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