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Bio 28: Nutrition Instructor: Paul Nagami Laney College
Bio 28: Nutrition Instructor: Paul Nagami Laney College

... Energy source: How many kcal of energy are there in a gram of carbs? ...
The Diagnosis of Gestational Diabetes - 1991
The Diagnosis of Gestational Diabetes - 1991

... GD in from 1% to more than 10% of pregnant women at 26 weeks1 or more gestation. Results of the 75g OGTT from a European multicentre study and from three clinics in Melbourne show that between 4% and 9% of pregnant women have a plasma glucose level of 8.0 mmol/L or more at two hours. In addition, fr ...
Management issues in hypertensive diabetics CPD Article
Management issues in hypertensive diabetics CPD Article

... major cardiovascular events in patients with and without diabetes mellitus.9 The results from this meta-analysis demonstrated that major cardiovascular events were reduced to a comparable extent in individuals with and without diabetes by regimens based on angiotensin-converting enzyme inhibitors (A ...
approach-DM-classification
approach-DM-classification

... for the Diagnosis of Diabetes Standardized and aligned to the DCCT/UKPDS Better index of overall glycemic exposure and risk for long-term complications ...
comments and responses - Diabetes Care
comments and responses - Diabetes Care

... as level-A evidence is based on a small number of patients in a single randomized study and on observational data (e.g., achieved glycemic levels) from most other randomized studies, this degree of confidence seems excessive to us. However, the ADVANCE study of ⬃11,000 type 2 diabetic patients with ...
Diabetes Type 1
Diabetes Type 1

... • Have a source of glucose readily available in the office. • Schedule short morning appointments. Ensure that patient has eaten a meal and taken usual medication prior to treatment. • Monitor vital signs at appointments. Patients with abnormal pulse rate and/or elevated blood pressure should b ...
Chronic Disease Management: Diabetes Mellitus
Chronic Disease Management: Diabetes Mellitus

... Mr. Smith came to the pharmacy this morning to pick up his refill prescription for lisinopril 10mg once daily, metformin 1000mg twice daily, and lispro insulin. This is the second time he has filled his insulin prescription. He did not receive diabetes education. He said that he often gets dizzy abo ...
Information Services Portal (ISP) | NHSBSA
Information Services Portal (ISP) | NHSBSA

... newer agents, glitazones, gliptins and exenatide, in type 2 diabetes mellitus is expected in May 2009. This guideline has the potential to have significant resource consequences for service providers. In 2008 three trials looking at intensive glucose control compared to standard glucose control were ...
U5L25 IDDM
U5L25 IDDM

... Intermediate – 1-2 hr – can take 6 h to peak Long acting – 3 h to onset, lasts 24 h – Zn2+ core • Mixtures – 70:30 long short ...
Ethical Issues of Predictive Genetic Testing for Diabetes
Ethical Issues of Predictive Genetic Testing for Diabetes

... • However, when effective therapy exists, the use of placebo control subjects does not meet the ethical standard • In these situations, the efficacy and safety of the experimental medication should be tested by blindly randomizing one group to the experimental drug and the other group to an existing ...
DiabetesType2_Chai
DiabetesType2_Chai

... Note: AMPK - an enzyme that plays an important role in insulin signaling, whole body energy balance, and the metabolism of glucose and fats. ...
Diabetes - 9/14
Diabetes - 9/14

... Exenatide (Byetta) is a GLP-1 mimetic derived from exendin,a closely related hormone (53% homologous) found in the saliva of the Gila monster. ...
Oxford BioDynamics picks Malaysia to conduct a biomarker
Oxford BioDynamics picks Malaysia to conduct a biomarker

... At each stage of the trial participants will provide a 15ml sample of blood, taken at the heal th cl i ni c through which they were recruited. The frozen samples will be delivered to the OBD reference facility in Penang where a profile of chromatin conformation signatures (CCSs) will be constructe d ...
Blood Glucose Regulation
Blood Glucose Regulation

... • 25.8 million people in the United States have diabetes– 8.3% of the population • If current trends continue, this rate will have grown to 30% by 2050. ...
Diabetes on Your OWN Terms! A Personal Approach To
Diabetes on Your OWN Terms! A Personal Approach To

... • Estimate number of insulin units you take in typical day • Divide total into 1,800 • Answer is insulin correction number – the amount of points a single unit of rapid-acting insulin should bring blood glucose level down within ~4 hours • Extremely empowering! ...
Diabetes Mellitus Type 2
Diabetes Mellitus Type 2

... gestation with 50g glucose load (non-fasting). It is extremely important to screen any woman, with past GDM, or glycosuria, or who is over 30 years, or obese or in a risk group for DM. If plasma glucose at 1h is ≥7.8 (≥8.0 if 75g load), then follow with formal OGTT. FPG ≥5.5 and 2h glucose ≥8.0 is d ...
Gene Therapy for Type 1 Diabetes Moves a Step Closer to Reality
Gene Therapy for Type 1 Diabetes Moves a Step Closer to Reality

... also had successful application in humans in other conditions requiring skeletal muscle expression such as hemophilia (8). In addition, success has been reported with this vector in clinical studies of Leber congenital amaurosis (9). Interestingly, the combination of insulin and glucokinase was nece ...
Spiritual Beliefs Effect on Patients with Type II Diabetes
Spiritual Beliefs Effect on Patients with Type II Diabetes

... a key role in lives of the subjects because God and the church have played a part in how the subjects cope with the disease and is the main support system for families. The subjects also have suffered from diet deprivation, physical, and emotional tiredness. Clinical Bottom Line: Both studies determ ...
Gut Tube and Digestion
Gut Tube and Digestion

... Inadequate or zero insulin production results in hyperglycemia or high blood sugar Overproduction or over-dosing of insulin results in hypoglycemia or low blood sugar--insulin shock Diabetes is insufficient production of insulin Type I--juvenile onset with elimination of Islets of langerhans and zer ...
Hyperglycemia Syndromes - UT Health Science Center
Hyperglycemia Syndromes - UT Health Science Center

... Correcting the hyperosmolar state and dehydration is the initial aim of therapy. Insulin therapy should be undertaken only after the patient is stable ...
Diabetes
Diabetes

... • Type 2 Diabetes – Persons with Diabetes Type 2 has one of two problems, and sometimes both: • Not enough insulin is being produced. • The insulin is not working properly - this is known as insulin resistance. – The vast majority of patients who develop Type 2 do so because they are overweight and ...
Caring for Individuals At Risk or Diagnosed with Diabetes and
Caring for Individuals At Risk or Diagnosed with Diabetes and

... • Type 2 Diabetes – Persons with Diabetes Type 2 has one of two problems, and sometimes both: • Not enough insulin is being produced. • The insulin is not working properly - this is known as insulin resistance. – The vast majority of patients who develop Type 2 do so because they are overweight and ...
Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus

... Random (non-fasting) blood glucose level diabetes is suspected if higher than 200 mg/dL and accompanied by the classic symptoms of increased thirst, urination, and fatigue. Oral glucose tolerance test - diabetes is diagnosed if glucose level is higher than 200 mg/dL after 2 hours. ...
Diagnostic Testing
Diagnostic Testing

... -Cultures of blood if sepsis is suspected and start antibiotics immediately -Alkalinization with intravenous sodium bicarbonate to keep pH >7.2 (there is no evidence that mortality rate is decreased). The use of sodium bicarbonate remains controversial. ...
Indications - Wings Herbal
Indications - Wings Herbal

... Some evidence also shows that a specific combination of biotin and chromium (Diachrome, Nutrition 21) might lower blood glucose levels and HbA1C levels in type 2 diabetes patients who are poorly controlled despite treatment with oral hypoglycaemic agents (10, 11, 16). However, there is no reliable ...
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Gemigliptin



Gemigliptin (rINN), previously identified as LC15-0444, is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. It is well known that glucose lowering effects of DPP-4 inhibitors are mainly mediated by GLP-1 and gastric inhibitory polypeptide (GIP) incretin hormones which are inactivated by DPP-4.Gemigliptin was initially developed solely by LG Life Sciences. In 2010, Double-Crane Pharmaceutical Co. (DCPC) joined with LGLS to co-develop the final compound and collaborate on the marketing of the drug in China. LGLS also announced on Nov., 2010 that NOBEL Ilac has been granted rights to develop and commercialize gemigliptin in Turkey.A New Drug Application (NDA) for gemigliptin in the treatment of type 2 diabetes was submitted to the Korea Food & Drug Administration (KFDA) in July 2011. Then on June 27, 2012, the KFDA has approved the manufacture and distribution of LG Life Sciences’ diabetes treatment, Zemiglo, the main substance of which is gemigliptin. Clinical trials for evaluating the safety and efficacy of gemigliptin in combination with metformin have been completed.
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