Ceramides: a new player in the insulin
... needed to put the interesting, but preliminary, findings from the present study into a broader context. Of course, should plasma ceramide concentrations adequately reflect tissue levels at key sites, this could accelerate studies examining their potential pathophysiological relevance to diabetes and ...
... needed to put the interesting, but preliminary, findings from the present study into a broader context. Of course, should plasma ceramide concentrations adequately reflect tissue levels at key sites, this could accelerate studies examining their potential pathophysiological relevance to diabetes and ...
PDF on diabetes
... Type 1 diabetes begins with autoimmune destruction of the pancreatic cells. However, an environmental trigger, perhaps a viral infection, is necessary to promote autoimmunity since genetic predisposition alone does not seem to be sufficient. Type 2 diabetes is characterized by peripheral insulin ...
... Type 1 diabetes begins with autoimmune destruction of the pancreatic cells. However, an environmental trigger, perhaps a viral infection, is necessary to promote autoimmunity since genetic predisposition alone does not seem to be sufficient. Type 2 diabetes is characterized by peripheral insulin ...
LONG TERM COMPLICATIONS OF DIABETES – A REVIEW
... higher for persons which are suffering of diabetes [4]. The risk of coronary heart disease for patients suffering of T1D increases dramatically with the onset of nephropathy. Up to 29% of T1D patients who developed nephropathy in childhood will develop a coronary disease in 20 years’ time, in compa ...
... higher for persons which are suffering of diabetes [4]. The risk of coronary heart disease for patients suffering of T1D increases dramatically with the onset of nephropathy. Up to 29% of T1D patients who developed nephropathy in childhood will develop a coronary disease in 20 years’ time, in compa ...
Type 2 Diabetes Mellitus in Children
... and weight control Telelink connections are very acceptable to parents and children Participation after school is preferable to office-based activities Minimal, if any stigma ...
... and weight control Telelink connections are very acceptable to parents and children Participation after school is preferable to office-based activities Minimal, if any stigma ...
Diabetic Emergencies
... A person with an altered level of consciousness may not have the protective reflex to prevent aspiration of oral contents into the lungs. As the brain approaches unconsciousness, it predisposes the person to a weakened glottic closure response. The ability to swallow is an effective indicator of the ...
... A person with an altered level of consciousness may not have the protective reflex to prevent aspiration of oral contents into the lungs. As the brain approaches unconsciousness, it predisposes the person to a weakened glottic closure response. The ability to swallow is an effective indicator of the ...
LOPROX (ciclopirox 0.77%): A novel approach to reducing the risk
... with the remaining amount to physicians, suppliers, outpatient hospitals, home health, SNF and hospice5. In a population of 10,000 individuals with diabetes, care for foot ulcerations to avoid amputations creates a 3-year savings ranging from $2,900-$4,442 per person with a history of foot ulcers6. ...
... with the remaining amount to physicians, suppliers, outpatient hospitals, home health, SNF and hospice5. In a population of 10,000 individuals with diabetes, care for foot ulcerations to avoid amputations creates a 3-year savings ranging from $2,900-$4,442 per person with a history of foot ulcers6. ...
EASD– Novo NorDiSk FouNDAtioN DiAbEtES PrizE For ExcEllENcE
... were able to stop their insulin and, remarkably, in every case their HbA1c improved without an increase in hypoglycaemia. These patients now had food-responsive insulin secretion and stable blood glucose concentrations. Removing the barriers by offering free testing The discovery that mutations in t ...
... were able to stop their insulin and, remarkably, in every case their HbA1c improved without an increase in hypoglycaemia. These patients now had food-responsive insulin secretion and stable blood glucose concentrations. Removing the barriers by offering free testing The discovery that mutations in t ...
(www.medknow.com). - Chronic Care Foundation
... The majority (97.7%) of patients had type 2 DM; only 2.3% had type 1 DM. Of the diabetic patients, 66% had one or more associated cutaneous manifestations. On the other hand, among the age and sex matched controls, only 21.3% had cutaneous manifestations. The cutaneous manifestations were thus posit ...
... The majority (97.7%) of patients had type 2 DM; only 2.3% had type 1 DM. Of the diabetic patients, 66% had one or more associated cutaneous manifestations. On the other hand, among the age and sex matched controls, only 21.3% had cutaneous manifestations. The cutaneous manifestations were thus posit ...
impact of sedentary lifestyle and waist
... drugs has been found without side effects and these drugs are costly too. As it is a multi factorial disease, no single method is sufficient to prevent it. In the present study 100 Diabetic patients were taken from different hospitals of central India to asses the role of life style and wc in diabet ...
... drugs has been found without side effects and these drugs are costly too. As it is a multi factorial disease, no single method is sufficient to prevent it. In the present study 100 Diabetic patients were taken from different hospitals of central India to asses the role of life style and wc in diabet ...
pulmonary infections in diabetes mellitus
... shunt. If more glucose enters the cells (hyperglycemia, diabetes mellitus), it is metabolized by the polyol pathway. Enzyme aldose-reductase, which is involved in the polyol pathway of glucose metabolism, also requires NADPH. Because of this competition for NADPH, the production of free radicals (re ...
... shunt. If more glucose enters the cells (hyperglycemia, diabetes mellitus), it is metabolized by the polyol pathway. Enzyme aldose-reductase, which is involved in the polyol pathway of glucose metabolism, also requires NADPH. Because of this competition for NADPH, the production of free radicals (re ...
rajiv gandhi university of health sciences
... To develop a patient-centred, group-based self-management program (X-PERT), based on theories of empowerment and discovery learning, and to assess the effectiveness of the programme on clinical, lifestyle and psychosocial outcomes. METHODS: Adults with Type 2 diabetes (n = 314), living in Burnley, P ...
... To develop a patient-centred, group-based self-management program (X-PERT), based on theories of empowerment and discovery learning, and to assess the effectiveness of the programme on clinical, lifestyle and psychosocial outcomes. METHODS: Adults with Type 2 diabetes (n = 314), living in Burnley, P ...
Diabetes Mellitus and Coronary Artery Bypass
... the phase of hypothermia there is higher insulin resistance of the tissues, which is particularly increased in the rewarming phase. Moreover, use of hypothermia suspends temporarily the hepatic glucose production, which restarts at the rewarming phase56,57. Administration of catecholamines (inotropi ...
... the phase of hypothermia there is higher insulin resistance of the tissues, which is particularly increased in the rewarming phase. Moreover, use of hypothermia suspends temporarily the hepatic glucose production, which restarts at the rewarming phase56,57. Administration of catecholamines (inotropi ...
Diabetes + Dialysis
... This requires data collection for six months prior to application. (For details about how to get ADA certified, visit www.diabetes.org/for-health-professionals-and-scientists/recognition/edrecognition.jsp.) ...
... This requires data collection for six months prior to application. (For details about how to get ADA certified, visit www.diabetes.org/for-health-professionals-and-scientists/recognition/edrecognition.jsp.) ...
Type 2 Diabetes - Carlisle Healthcare
... a diet low in fat, salt and sugar and high in fibre and with plenty of fruit and vegetables. Lose weight if you are overweight . Getting to a perfect weight is unrealistic for many people. However, losing some weight if you are obese or overweight will help to reduce your blood glucose level (and ha ...
... a diet low in fat, salt and sugar and high in fibre and with plenty of fruit and vegetables. Lose weight if you are overweight . Getting to a perfect weight is unrealistic for many people. However, losing some weight if you are obese or overweight will help to reduce your blood glucose level (and ha ...
Medication Nonadherence and the Risks of Hospitalization
... glucose monitoring, and multiple medications to prevent complications. To our knowledge, our study is one of the very few that evaluated adherence to multiple medications essential to the management of diabetes.16,22 Ho and associates16 studied the effect of medication nonadherence on all-cause hosp ...
... glucose monitoring, and multiple medications to prevent complications. To our knowledge, our study is one of the very few that evaluated adherence to multiple medications essential to the management of diabetes.16,22 Ho and associates16 studied the effect of medication nonadherence on all-cause hosp ...
fundamentals: ebp - diabetic ketoacidosis
... Hopefully, serum sodium levels will correct during rehydration of the patient, but if not, then proper replacement of the electrolytes would be considered after initial fluid and insulin replacement. During insulin administration, potassium is pushed into cells, causing hypokalemia, which means that ...
... Hopefully, serum sodium levels will correct during rehydration of the patient, but if not, then proper replacement of the electrolytes would be considered after initial fluid and insulin replacement. During insulin administration, potassium is pushed into cells, causing hypokalemia, which means that ...
Exercise Management
... blood glucose is above 250 mg/dl and ketones are present (blood glucose should be lowered before initiation of exercise) or blood glucose is < 70 mg/dl because the risk of hypoglycemia is great (if postexercise blood glucose is < 100 mg/dl, carbohydrate should be eaten and blood glucose allowed t ...
... blood glucose is above 250 mg/dl and ketones are present (blood glucose should be lowered before initiation of exercise) or blood glucose is < 70 mg/dl because the risk of hypoglycemia is great (if postexercise blood glucose is < 100 mg/dl, carbohydrate should be eaten and blood glucose allowed t ...
Anaesthetic management of patients with DM
... perhaps via a specific receptor mechanism. The -glucosidase inhibitor, acarose, suppresses the breakdown of complex carbohydrates in the gut and therefore delays the rise in postprandial blood glucose concentrations. Intensive, effective glycemic control of type 2 diabetes results in a reduction of ...
... perhaps via a specific receptor mechanism. The -glucosidase inhibitor, acarose, suppresses the breakdown of complex carbohydrates in the gut and therefore delays the rise in postprandial blood glucose concentrations. Intensive, effective glycemic control of type 2 diabetes results in a reduction of ...
A Variant of the Transcription Factor 7- Like 2
... genotype (41.4 vs. 22.2%) (odds ratio 2.474 [95% CI 1.146 –5.341]; P ⫽ 0.024) (Table 3). Unlike other studies on TCF7L2, no patients with the TT genotype were identified in this study. There was no difference between genotypes with regard to age at transplantation; initial body weight; FPG at baseli ...
... genotype (41.4 vs. 22.2%) (odds ratio 2.474 [95% CI 1.146 –5.341]; P ⫽ 0.024) (Table 3). Unlike other studies on TCF7L2, no patients with the TT genotype were identified in this study. There was no difference between genotypes with regard to age at transplantation; initial body weight; FPG at baseli ...
Diabetes Overview - Cleveland Clinic Center for Continuing Education
... How is diabetes diagnosed? If you suddenly experience symptoms of increased thirst, frequent urination, or unexplained weight loss, diabetes may be the cause. To confirm the diagnosis, a fasting plasma glucose (FPG) test, a casual plasma glucose test, or an A1c test (glycated hemoglobin) will be per ...
... How is diabetes diagnosed? If you suddenly experience symptoms of increased thirst, frequent urination, or unexplained weight loss, diabetes may be the cause. To confirm the diagnosis, a fasting plasma glucose (FPG) test, a casual plasma glucose test, or an A1c test (glycated hemoglobin) will be per ...
Diabetic Retinopathy - Diabetes Care
... EURODIAB Controlled Trial of Lisinopril in Insulin Dependent Diabetes (EUCLID) study group investigated the effect of lisinopril on retinopathy in type 1 diabetes. Eligible patients were not hypertensive, and were normoalbuminuric (85%) or microalbuminuric. The proportion of patients with retinopath ...
... EURODIAB Controlled Trial of Lisinopril in Insulin Dependent Diabetes (EUCLID) study group investigated the effect of lisinopril on retinopathy in type 1 diabetes. Eligible patients were not hypertensive, and were normoalbuminuric (85%) or microalbuminuric. The proportion of patients with retinopath ...
Serum Vitamin D levels in Diabetics and its correlation with Diabetic
... The incidence of this disease continues to rise all over the world. Diabetes is recognized to be common in Asian Indians. The magnitude of problem is further compounded by various catastrophic microvascular and macrovascular complications targeting the vital organs in the body. DM is the leading cau ...
... The incidence of this disease continues to rise all over the world. Diabetes is recognized to be common in Asian Indians. The magnitude of problem is further compounded by various catastrophic microvascular and macrovascular complications targeting the vital organs in the body. DM is the leading cau ...
Full Article (PDF file) - Journal of Gastrointestinal and
... to esophageal and duodenal causes; patients who did not have EGD or UGIS prior to a GES. In patients who had multiple gastric emptying studies, only the index study was included. Data acquisition All data was obtained from review of a state-of-the-art electronic medical record (EMR) system in place ...
... to esophageal and duodenal causes; patients who did not have EGD or UGIS prior to a GES. In patients who had multiple gastric emptying studies, only the index study was included. Data acquisition All data was obtained from review of a state-of-the-art electronic medical record (EMR) system in place ...
pre-diabetes - Indiana Pharmacists Alliance
... Prevent Diabetes STAT: Screen, Test, Act – Today A multi-year initiative that expands on each organization’s work to reach more Americans with pre-diabetes and stop the progression to type 2 diabetes. “The time to act is now. We need a national, concerted effort to prevent additional cases of type 2 ...
... Prevent Diabetes STAT: Screen, Test, Act – Today A multi-year initiative that expands on each organization’s work to reach more Americans with pre-diabetes and stop the progression to type 2 diabetes. “The time to act is now. We need a national, concerted effort to prevent additional cases of type 2 ...
Coconuthead
... there. Be more general before getting specific is when the body’s pancreas stops producing insulin for the body.-Should you introduce what diabetes is first? Maybe a bit about what insulin is as well. How the system works. The main goal for a diabetic person is to maintain stable blood glucose level ...
... there. Be more general before getting specific is when the body’s pancreas stops producing insulin for the body.-Should you introduce what diabetes is first? Maybe a bit about what insulin is as well. How the system works. The main goal for a diabetic person is to maintain stable blood glucose level ...
Gemigliptin
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Gemigliptin (rINN), previously identified as LC15-0444, is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. It is well known that glucose lowering effects of DPP-4 inhibitors are mainly mediated by GLP-1 and gastric inhibitory polypeptide (GIP) incretin hormones which are inactivated by DPP-4.Gemigliptin was initially developed solely by LG Life Sciences. In 2010, Double-Crane Pharmaceutical Co. (DCPC) joined with LGLS to co-develop the final compound and collaborate on the marketing of the drug in China. LGLS also announced on Nov., 2010 that NOBEL Ilac has been granted rights to develop and commercialize gemigliptin in Turkey.A New Drug Application (NDA) for gemigliptin in the treatment of type 2 diabetes was submitted to the Korea Food & Drug Administration (KFDA) in July 2011. Then on June 27, 2012, the KFDA has approved the manufacture and distribution of LG Life Sciences’ diabetes treatment, Zemiglo, the main substance of which is gemigliptin. Clinical trials for evaluating the safety and efficacy of gemigliptin in combination with metformin have been completed.