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Supplementary Methods and Reference
Supplementary Methods and Reference

... Through four serial passages (p4), human lung cancer A549 cell-derived spheres were transferred back to adhesive tissue culture plates, after which they migrated back onto plates and reformed a monolayer with morphological heterogeneity [and were then collected as lowmotility (LM) cells] (1). To est ...
Anti HumanGlubulin
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Lecture 2: Cellular signalling and cell division
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... For example Vg1 mRNA is synthesized in the oocyte and become localized in vegetal cortical region of egg. An injection of mRNA coding the active Vg1 protein in the ventral blastomere can induce an entire body axis. Morphogens: the biochemical species responsible for differentian The gradient of mor ...
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Extracellular matrix



In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).
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