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A Class of Human Proteins that Deliver Functional
A Class of Human Proteins that Deliver Functional

... N-DEK, and N-HGF (Figure 1A). b-defensin 3 is an extracellular antimicrobial protein (see Table S1A available online) (Harder et al., 2001). HRX, c-Jun, and N-DEK are nuclear proteins known to interact with DNA (Glover and Harrison, 1995; Hollenbach et al., 2002; Nakamura et al., 2002). HBEGF and N- ...
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Alfalfa Mob1-like proteins are involved in cell

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Extracellular matrix



In biology, the extracellular matrix (ECM) is a collection of extracellular molecules secreted by cells that provides structural and biochemical support to the surrounding cells. Because multicellularity evolved independently in different multicellular lineages, the composition of ECM varies between multicellular structures; however, cell adhesion, cell-to-cell communication and differentiation are common functions of the ECM.The animal extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.The plant ECM includes cell wall components, like cellulose, in addition to more complex signaling molecules. Some single-celled organisms adopt multicelluar biofilms in which the cells are embedded in an ECM composed primarily of extracellular polymeric substances (EPS).
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