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Cell Structure and Function
Cell Structure and Function

... cause the dynein arms to repeatedly bind the adjacent pair of microtubules, bend, and then disengage. The dynein arms “walk” along the microtubules. Their motion causes adjacent microtubule pairs to slide past one another ...
The Cortical Microtubule Array: From Dynamics to
The Cortical Microtubule Array: From Dynamics to

... important consideration when trying to understand the relationship between microtubule assembly dynamics and organization. Microtubules possess an inherent polarity as a result of the head-to-tail assembly of the a/b-tubulin subunits during polymerization (Figure 1A). This structural polarity forms ...
Review questions: Week 1 Nonet * cell biology Nonet * axon
Review questions: Week 1 Nonet * cell biology Nonet * axon

... release in just a few steps, starting with an action potential in the presynaptic neuron ...
05 Cytoskeleton
05 Cytoskeleton

... anchors some organelles and directs the movement of others, ...
How do cells position their division plane?
How do cells position their division plane?

... Metaphase ...
Why do cells reproduce?
Why do cells reproduce?

... Why do cells divide? Cell reproduction in prokaryotes Cell cycle Chromosome structure Cell Division: Mitosis & Cytokinesis Cancer & Cell Division ...
Plant chaperonins: a role in microtubule
Plant chaperonins: a role in microtubule

... microtubule nucleation such as nuclear envelope and preprophase band. In addition, CCT~ was associated with tubulin in sites of elevated wall synthesis such as phragmoplast or along secondary-wall thickenings. CCTr and its substrate tubulin were found to be soluble during periods of cytoskeletal dyn ...
05lctout - Evergreen Archives
05lctout - Evergreen Archives

... 2. Studies involving lysosomal enzymes have revealed that these proteins are tagged with specific carbohydrate groups (mannose-6-phosphate) (Fig. 5.10) that act as molecular “zip codes” targeting the proteins to vesicles that are destined for the lysosome. (Fig. 5.12) V. The Cytoskeleton A. Microfil ...
Slide ()
Slide ()

... Organelles of the neuron. Electron micrographs show cytoplasm in four different regions of the neuron. (Adapted, with permission, from Peters et al. 1991.) A. A dendrite emerges from a pyramidal neuron's cell body, which includes the endoplasmic reticulum (ER) above the nucleus (N) and a portion of ...
How migration occurs
How migration occurs

... 1.works like p65PAK,leading to stabilization of actin filaments within actin:myosin filament bundles. 2.interacts with and phosphorylates the myosin binding subunit of myosin light chain phosphatase and inactivates it,leading to increased levels of myosin phosphorylation, which then can crosslink ac ...
Slide 1
Slide 1

... I. Cells are the basic units of life and fall under 2 categories. A. Prokaryotic cells have a nucleoid (area where DNA is concentrated) instead of a nucleus and do not have membrane-bound organelles. They are also generally smaller and simpler. An example is bacteria. B. Eukaryotic cells have a nucl ...
Dr. Elisar Barbar`s Lab - Oregon State University
Dr. Elisar Barbar`s Lab - Oregon State University

... Motor Proteins • Motor proteins are the cell’s transportation system • Dynein and Kinesin are the two primary classes of motor proteins – They are powered by ATP and “walk” along microtubules transporting their cargo ...
Objectives Key Terms The Mitosis Dance
Objectives Key Terms The Mitosis Dance

... prophase, the nuclear envelope breaks down. Meanwhile, in the cytoplasm, a footballshaped structure called the mitotic spindle forms. The chromatids now attach to the microtubules that make up the spindle. The spindle starts tugging the chromosomes toward the center of the cell for the next step in ...
A plant cell consists of many organelles. Each one of them plays its
A plant cell consists of many organelles. Each one of them plays its

... fruits and vegetables are orange or red when they ripen. Vacuole- every plant cell has only one large vacuole. It helps in plant growth. The vacuole also plays a very important structure for the plant. Chloroplasts- the chloroplast allows the important process of photosynthesis to occur. This is whe ...
File
File

... enzymes (cyclindependent kinases) ...
Plant microtubule organization
Plant microtubule organization

... assembly, orientation and function. We tend to think first about microtubules as the major structural components of mitotic spindles and flagellae. In these cases, microtubules emanate from centrosomes, microtubule-nucleating complexes that are focused around a microtubule-derived apparatus known as ...
final1-fp7-people-ief-2015-huber-final-report-02
final1-fp7-people-ief-2015-huber-final-report-02

... We find that a strongly reduced stochastic description of the MT tip is sufficient to qualitatively and quantitatively explain a diverse collection of data on growing MTs under different conditions (with and without EB), in the presence or absence of rigid obstacles. This will allow us to propose a ...
Motor Proteins and The Cytoskeleton
Motor Proteins and The Cytoskeleton

... -Localize Golgi Axonemal Dynein Motion of Cilia and Flagella ...
Lecture 1
Lecture 1

... Cytoskeletal proteins can be labeled with fluorescently tagged (conjugated) antibodies, which bind with high affinity and specificity. (Usually in fixed cells) – Can be done in living cells to investigate function of a specific filament system ...
08. Cell Organelle II
08. Cell Organelle II

... for photosynthesis - internal organization: elliptical shape with internal stroma; pigment photosystems are highly ordered and arrayed on thylakoids (membranes with granal & intergranal regions) ...
Mitotic cell cycle – arrange the diagrams of the stages of mitosis into
Mitotic cell cycle – arrange the diagrams of the stages of mitosis into

... Interphase. The cell is engaged in metabolic activity and performing its duty as part of a tissue. The DNA duplicates during interphase to prepare for mitosis (the next four phases that lead up to and include nuclear division). Chromosomes are not clearly visible in the nucleus, although the nucleol ...
mitosis card game - Biology Junction
mitosis card game - Biology Junction

... Spindle and centrosomes disappear ...
Mitosis in a bag
Mitosis in a bag

... Spindle and centrosomes disappear ...
equisetum - Natuurtijdschriften
equisetum - Natuurtijdschriften

... Microtubules and microfibril orientation ...
C-Tubulin in Barley and Tobacco: Sequence Relationship and RNA
C-Tubulin in Barley and Tobacco: Sequence Relationship and RNA

... from the unicellular green alga Chlamydomonas. The archegoniates Anemia and Physcomitrella formed a cluster, as did the angiosperms. Within the angiosperms a cluster corresponded to dicots and another to monocots or, more precisely, to grasses. A comprehensive sequence alignment including gtubulin s ...
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Microtubule



Microtubules (micro- + tube + -ule) are a component of the cytoskeleton, found throughout the cytoplasm. These tubular polymers of tubulin can grow as long as 50 micrometres and are highly dynamic. The outer diameter of a microtubule is about 24 nm while the inner diameter is about 12 nm. They are found in eukaryotic cells and are formed by the polymerization of a dimer of two globular proteins, alpha and beta tubulin.Microtubules are very important in a number of cellular processes. They are involved in maintaining the structure of the cell and, together with microfilaments and intermediate filaments, they form the cytoskeleton. They also make up the internal structure of cilia and flagella.They provide platforms for intracellular transport and are involved in a variety of cellular processes, including the movement of secretory vesicles, organelles, and intracellular macromolecular assemblies (see entries for dynein and kinesin). They are also involved in chromosome separation (mitosis and meiosis), and are the major constituents of mitotic spindles, which are used to pull apart eukaryotic chromosomes.Microtubules are nucleated and organized by microtubule organizing centers (MTOCs), such as the centrosome found in the center of many animal cells or the basal bodies found in cilia and flagella, or the spindle pole bodies found in fungi.There are many proteins that bind to microtubules, including the motor proteins kinesin and dynein, severing proteins like katanin, and other proteins important for regulating microtubule dynamics.
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