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Nature Rev.Genet
Nature Rev.Genet

... from Cedar and Bergman, Nature Rev.Genet. 10, 295 (2009) Repressive histone methylation marks must be removed, followed by removal of DNA methylation which activates the gene ...
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Disability Theory in A Separate Peace
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Supplemental Figure 1. Log2 signal and Z
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... Supplemental Figure 1. Log2 signal and Z-score heat maps of individual genes discussed in text. The signal heat map on the left indicates the log2 signal for each gene colored from low (blue) to high (red). The blue to red transition point (black) was chosen as 7, which equals the log2 of a signal i ...
DNA Assignment
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Wiki - DNA Fingerprinting, Individual Identification and Ancestry
Wiki - DNA Fingerprinting, Individual Identification and Ancestry

... based on their DNA, has become central to forensics, paternity testing, conservation biology, evolutionary biology and ancestry research. It would be hard to find a television episode of CSI that doesn't mention this technology. But what is a genetic or DNA fingerprint? How accurate are they? How mu ...
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... typically have the same number of chromosomes. Humans have 46 chromosomes. The domestic dog has 78 chromosomes, the domestic cat has 38 chromosomes, and the mouse that it chases has 40 chromosomes! Within each individual in a species, every somatic cell (not a sex cell) contains the same number of c ...
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... this antibiotic have been isolated and shown to have an altered RNA polymerase. • Untreated culture To select for spontaneous rifampicinresistant mutations: Spread 0.2 ml of undiluted culture on an L plate that contains rifampicin (100 g/ml). Set up a total of 2 such plates. Place the plates at 37o ...
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... 65. Chromosomes that are the same length, have the same centromere position and staining pattern are called ____homologous_____________ chromosomes. 66. Cells that have only a single set of chromosomes are called __haploid___________. 67. A picture of an organism’s chromosomes is called a ___karyoty ...
2015/5/13 9:24 AM
2015/5/13 9:24 AM

... 32. Viruses have a simple cellular structure. 33. In general, viral replication involves production of viral proteins and assembly of viral particles within a host cell. 34. A promoter is a binding site for DNA polymerase. 35. Prokaryotes genes turn on or off in response to genetic factors. 36. Spec ...
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Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
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