Epigenetics
... X:autosome translocation • In this case, X-inactivation is not random - the normal X is always inactivated, because the translocation interferes with the inactivation process • Therefore, the normal DMD gene is switched off, and the other one is disrupted by the translocation • So these girls show t ...
... X:autosome translocation • In this case, X-inactivation is not random - the normal X is always inactivated, because the translocation interferes with the inactivation process • Therefore, the normal DMD gene is switched off, and the other one is disrupted by the translocation • So these girls show t ...
13-3 Cell Transformation
... Transforming Plant Cells Bacterial plasmids can be used to transform plant cells. Agrobacterium tumefaciens Type of bacteria that inserts a plasmid into plant cells and grows tumors. The tumor-producing gene can be removed and replaced with recombinant DNA. If transformation is successfu ...
... Transforming Plant Cells Bacterial plasmids can be used to transform plant cells. Agrobacterium tumefaciens Type of bacteria that inserts a plasmid into plant cells and grows tumors. The tumor-producing gene can be removed and replaced with recombinant DNA. If transformation is successfu ...
2 Types of Selective Breeding
... 1) Selective Breeding – a process of selecting a few organisms with _______________ to serve as parents of the ___________ EX: Cows that ___________ milk, vegetables that _____________ 2 Types of Selective Breeding 1) ____________________ – crossing 2 individuals with similar sets of genes to produc ...
... 1) Selective Breeding – a process of selecting a few organisms with _______________ to serve as parents of the ___________ EX: Cows that ___________ milk, vegetables that _____________ 2 Types of Selective Breeding 1) ____________________ – crossing 2 individuals with similar sets of genes to produc ...
Transformation and Transduction File
... the uptake of foreign DNA from its surroundings. For example, bacteria from a harmless strain of Streptococcus pneumoniae can be transformed to pneumonia causing cells if ...
... the uptake of foreign DNA from its surroundings. For example, bacteria from a harmless strain of Streptococcus pneumoniae can be transformed to pneumonia causing cells if ...
12 transgenic mice
... species is pigmented, it is easy to see which offspring are chimeric. This technology is used to generate knock out mice, where all copies of a specific gene are knocked out or made non functional. This method is more efficient than injection into pronuclei . How is this done? ...
... species is pigmented, it is easy to see which offspring are chimeric. This technology is used to generate knock out mice, where all copies of a specific gene are knocked out or made non functional. This method is more efficient than injection into pronuclei . How is this done? ...
Double helix- a double twist
... helped people? Why is it important to know what genes we have- how has this changed medicine? ● Proteins o What are proteins made of? (what is the smaller building block) ...
... helped people? Why is it important to know what genes we have- how has this changed medicine? ● Proteins o What are proteins made of? (what is the smaller building block) ...
Kyle Snell
... expression patterns that would not be possible in a diploid. Recently, the significance of endopolyploidy, or “cell polyploidy,” in plants has begun to receive more attention. Endopolyploid cells contain at minimum a doubling of the base nuclear DNA of the plant, and have only been found in select t ...
... expression patterns that would not be possible in a diploid. Recently, the significance of endopolyploidy, or “cell polyploidy,” in plants has begun to receive more attention. Endopolyploid cells contain at minimum a doubling of the base nuclear DNA of the plant, and have only been found in select t ...
Student Worksheet
... Read the authors’ conclusions below, and with a partner discuss how these conclusions could be relevant for humans and summarize in your own words below. “In the present study, we observed a statistically significant shift in coat-color phenotype and adult body weight distribution among genetically ...
... Read the authors’ conclusions below, and with a partner discuss how these conclusions could be relevant for humans and summarize in your own words below. “In the present study, we observed a statistically significant shift in coat-color phenotype and adult body weight distribution among genetically ...
File - Ms. Pennington Pre
... C. parts of the silencing complex that regulates gene action through RNA interference. D. base sequences complementary to sequences in microRNA. 13. What role do homeobox genes play in cell differentiation? A. They code for transcription factors that activate other genes important in cell developmen ...
... C. parts of the silencing complex that regulates gene action through RNA interference. D. base sequences complementary to sequences in microRNA. 13. What role do homeobox genes play in cell differentiation? A. They code for transcription factors that activate other genes important in cell developmen ...
Lecture 22
... ii. Bacterial DNA repair includes enzyme that will resolve conflict when a set repeats >1 Watson-Crick double stranded DNA iii. Diagram iv. Enzyme sees ambiguous 4 strand region and cuts strand to resolve tangle v. Note: non-reciprocal recombination does not result in two copies or two chromatids, ...
... ii. Bacterial DNA repair includes enzyme that will resolve conflict when a set repeats >1 Watson-Crick double stranded DNA iii. Diagram iv. Enzyme sees ambiguous 4 strand region and cuts strand to resolve tangle v. Note: non-reciprocal recombination does not result in two copies or two chromatids, ...
1) Genetics Vocabulary
... divisions of the nucleus, producing four sex cells, each having half the number of chromosomes as the original cell. Mitosis – cell division process in which DNA in the nucleus is duplicated and the nucleus divides into two nuclei that contain the same genetic information. Mutation – change in a gen ...
... divisions of the nucleus, producing four sex cells, each having half the number of chromosomes as the original cell. Mitosis – cell division process in which DNA in the nucleus is duplicated and the nucleus divides into two nuclei that contain the same genetic information. Mutation – change in a gen ...
Biotechnology
... whether or not a young woman carries one or two copies of a mutant gene • This gene is called p53. The mutated version is linked to colon cancer. • How do you think we will go about this? – RFLPs and gel electrophoresis ...
... whether or not a young woman carries one or two copies of a mutant gene • This gene is called p53. The mutated version is linked to colon cancer. • How do you think we will go about this? – RFLPs and gel electrophoresis ...
VI. Genetic Engineering or Recombinant DNA Technology
... 2. Protoplasts minus their walls can then fuse or hybridize 3. Hybrid cells can be selected for and cultured 4. Somatic hybrids are the result of a fusion from two different protoplasts E. Clonal Variants 1. Cells with slightly different characteristics are frequently found in cultures 2. Variant ce ...
... 2. Protoplasts minus their walls can then fuse or hybridize 3. Hybrid cells can be selected for and cultured 4. Somatic hybrids are the result of a fusion from two different protoplasts E. Clonal Variants 1. Cells with slightly different characteristics are frequently found in cultures 2. Variant ce ...
Intro to DNA
... Intro to DNA • NOTE: • “matching pairs” of chromosomes • = “homologous pairs”. • In every human somatic cell, there are 23 homologous pairs of chromosomes. ...
... Intro to DNA • NOTE: • “matching pairs” of chromosomes • = “homologous pairs”. • In every human somatic cell, there are 23 homologous pairs of chromosomes. ...
Genetics and Health
... Insertion Point mutation PROTEIN Non-sense (STOP) Mis-sence Silent ...
... Insertion Point mutation PROTEIN Non-sense (STOP) Mis-sence Silent ...
basic characterisation of hiPSC.
... BSCC will provide a basic characterization of hiPSC including: ...
... BSCC will provide a basic characterization of hiPSC including: ...
Lecture 6
... • Statistical analysis of the rates of homologous recombination of several different genes could determine their order on a certain chromosome, and information from many such experiments could be combined to create a genetic map specifying the rough location of known genes relative to each other. • ...
... • Statistical analysis of the rates of homologous recombination of several different genes could determine their order on a certain chromosome, and information from many such experiments could be combined to create a genetic map specifying the rough location of known genes relative to each other. • ...
Untitled
... e) Humans have 46 chromosomes per diploid cell and chimps have 48. Still, the species are considered to be very closely related. What accounts for the numerical difference and what suggests ‘close relationship’.? The apes have 2 one armed chromsomes that fused (Robertsonian translocation to become o ...
... e) Humans have 46 chromosomes per diploid cell and chimps have 48. Still, the species are considered to be very closely related. What accounts for the numerical difference and what suggests ‘close relationship’.? The apes have 2 one armed chromsomes that fused (Robertsonian translocation to become o ...
Site-specific recombinase technology
Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse