• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
DNA and the Genome - Speyside High School
DNA and the Genome - Speyside High School

... Multi-cellular organisms are comprised of a large number of cells. These are specialised to carry out specific roles in the body. Differentiation is the process by which unspecialised cells become altered and adapted to form a special function in the body. CFE Higher Biology ...
When we talk about gene position the term is used to designate the
When we talk about gene position the term is used to designate the

... expected numbers of each type of progeny. For example, if you know that two mutations are 12 cM apart then you should expect that 6% of the progeny from a cross will be of each of recombinant class. Things get interesting when we make several pairwise crosses between genes on the same chromosome. We ...
Example of BLASTN output
Example of BLASTN output

... The title of this primary literature journal article suggests that the authors did experiments to show that the house fly sequence is equivalent to the Drosophila sequence. We can click on the link (9376318) to see the Abstract from the journal article. The abstract is a concise summary of the infor ...
Directed Reading B
Directed Reading B

... Directed Reading B Section: How DNA Works Circle the letter of the best answer for each question. ...
Molecular Genetics 2 - New York University
Molecular Genetics 2 - New York University

... Associating inherited (DNA) variation with biological variation • Each person’s genome is slightly different • Some differences alter biological function ...
Genome Analysis - Bayerische Landesanstalt für Landwirtschaft
Genome Analysis - Bayerische Landesanstalt für Landwirtschaft

... genes for powdery mildew (PM). So far using the AFLP technique several markers in close linkage to the R2 gene from Wye Target and also sex differentiating markers have been identified. In addition to this efficient method, a differential display approach in combination with the cDNAAFLP method was ...
BIOL10005: Genetics and the Evolution of Life
BIOL10005: Genetics and the Evolution of Life

... Interaction between two genes affecting the same phenotypic trait, where the homozygous recessive genotype at one locus masks the effect of the alleles at the other locus, e.g. coat colour in mice Interaction between two genes affecting the same phenotypic trait, where the allele for the dominant tr ...
Child Psychology, Second Canadian Edition
Child Psychology, Second Canadian Edition

... • Mitosis refers to a process by which 2 identical cells are produced • Meiosis refers to a process in 4 cells are produced, with each containing only 23 chromosomes Figure 3.1 (Mitosis and meiosis. Mitosis results in two cells identical with the parent and with each other. Meiosis results in four ...
Genetics Vocabulary 2014-2015
Genetics Vocabulary 2014-2015

... recessive allele – an allele that is masked when a dominant allele is present hybrid – an organism that has two different alleles for a trait phenotype – an organism’s physical appearance or visible traits gentotype – an organism’s genetic makeup or allele combinations homozygous – having two identi ...
Mutations that happen during Transcription and
Mutations that happen during Transcription and

... • Enzymes proofread the DNA and replace incorrect nucleotides with correct nucleotides. • The greater the exposure to a mutagen such as UV light, the more likely is the chance that a mistake will not be corrected. ...
“Evolution Practice Test” Vocabulary: Define the following
“Evolution Practice Test” Vocabulary: Define the following

... 2. Explain how natural selection causes evolution. Discuss the ideas of inheritance, competition and mutation in your response. ...
Supplementary Methods - Cancer Prevention Research
Supplementary Methods - Cancer Prevention Research

... It is well known that application of an algorithm to the data on which it was trained gives an overly optimistic estimate of performance. Cross validation is designed to give a more accurate estimate of performance using training data sets only slightly smaller than the original data. Briefly K-fold ...
Gene pool
Gene pool

... will remain constant (i.e. unchanging) over generations as long as there is: 1. no selection 2. no mutations 3. no gene flow 4. no genetic drift 5. random mating  If these conditions are met, the pop. is @ equilibrium ...
Gene Section ADAM23 (ADAM metallopeptidase domain 23) Atlas of Genetics and Cytogenetics
Gene Section ADAM23 (ADAM metallopeptidase domain 23) Atlas of Genetics and Cytogenetics

Chromosome structure File
Chromosome structure File

... Chromosomes in eukaryotes are located in the nucleus ...
DNA Sequencing: Importance
DNA Sequencing: Importance

... Edible vaccines incorporated into food products New environmental cleanup uses for plants like tobacco. ...
The Major Transitions in Evolution
The Major Transitions in Evolution

... are less common but consistent with social transmission, and ‘absent’ acts are those missing with no apparent straightforward environmental explanation. • Traditions are defined as behaviour patterns that are customary or habitual in at least one site but absent elsewhere. • Transmission is attribut ...
mobile genetic elements and cancer. from mutations to gene therapy
mobile genetic elements and cancer. from mutations to gene therapy

... ME numbers in a genome stimulate the formation of deletions, duplications, inversions, or translocations as a result of ectopic recombination [25–27]. Therefore, the effect of MEs on the human genome is diverse: MEs often take part in important genomic functions and provide material for natural sele ...
The Major Transitions in Evolution
The Major Transitions in Evolution

... are less common but consistent with social transmission, and ‘absent’ acts are those missing with no apparent straightforward environmental explanation. • Traditions are defined as behaviour patterns that are customary or habitual in at least one site but absent elsewhere. • Transmission is attribut ...
human genetics - local.brookings.k12.sd.us
human genetics - local.brookings.k12.sd.us

... More common in males (8% of males are colorblind) Can’t distinguish certain colors Most common = red/green ...
HIV GENOTYPE ASSAY
HIV GENOTYPE ASSAY

... provides reagents for viral RNA isolation from plasma, RT-PCR, and sequencing. The entire protease gene and two-thirds of the Rt gene are amplified to generate a 1.8 kb amplicon. The amplicon is used as a sequencing template for seven primers that generate an approx. 1.3 kb consensus sequence. The s ...
AND DNA Genes are located on chromosomes in the nucleus of
AND DNA Genes are located on chromosomes in the nucleus of

... • The four bases are adenine, thymine, guanine, and cytosine. (Bram, this is very fundamental) • Adenine binds to thymine while guanine binds to cytosine. (This too is most fundamental). ...
Nutrigenomics and nutrigenetics – are they the keys for healthy
Nutrigenomics and nutrigenetics – are they the keys for healthy

... critical genes. Folate and vitamin B12 contribute to generating 5methyltetrahydrofolate (5-MTHF), which provides the methyl group for synthesis of methionine and SAM, the universal methyl donor of biological methylation. DNA methylation inhibits gene expression. „Food and nutrition in 21st century”, ...
Species PwrPnt
Species PwrPnt

... • Phenotype frequency= # certain phenotype/# people ...
Mendel and The Gene Idea
Mendel and The Gene Idea

... Dominant/Recessive Relationships 1. Range from complete dominance through various degrees of incomplete dominance, to codominance. 2. Reflect mechanisms by which specific alleles are expressed in phenotype and do not involve the ability of one allele to subdue another at the level of the DNA. 3. Th ...
< 1 ... 1055 1056 1057 1058 1059 1060 1061 1062 1063 ... 1288 >

Site-specific recombinase technology



Nearly every human gene has a counterpart in the mouse (regardless of the fact that a minor set of orthologues had to follow species specific selection routes). This made the mouse the major model for elucidating the ways in which our genetic material encodes information. In the late 1980s gene targeting in murine embryonic stem (ES-)cells enabled the transmission of mutations into the mouse germ line and emerged as a novel option to study the genetic basis of regulatory networks as they exist in the genome. Still, classical gene targeting proved to be limited in several ways as gene functions became irreversibly destroyed by the marker gene that had to be introduced for selecting recombinant ES cells. These early steps led to animals in which the mutation was present in all cells of the body from the beginning leading to complex phenotypes and/or early lethality. There was a clear need for methods to restrict these mutations to specific points in development and specific cell types. This dream became reality when groups in the USA were able to introduce bacteriophage and yeast-derived site-specific recombination (SSR-) systems into mammalian cells as well as into the mouse
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report