Full Text - IDOSI Publications
... Abstract: This research investigated the effect of leaf extracts of Alchornea cordifolia on fertility hormones in albino rats. The dried leaf extracts were prepared with deionised water and ethylacetate. Chemical analyses of the extracts were performed using standard methods. The effects of the extr ...
... Abstract: This research investigated the effect of leaf extracts of Alchornea cordifolia on fertility hormones in albino rats. The dried leaf extracts were prepared with deionised water and ethylacetate. Chemical analyses of the extracts were performed using standard methods. The effects of the extr ...
Apo-Cimetidine - DavisPlus
... Short-term treatment of active duodenal ulcers and benign gastric ulcers. Maintenance therapy for duodenal ulcers after healing of active ulcer(s). Management of gastroesophageal reflux disease (GERD). Treatment of heartburn, acid indigestion, and sour stomach (OTC use). Management of gastric hypers ...
... Short-term treatment of active duodenal ulcers and benign gastric ulcers. Maintenance therapy for duodenal ulcers after healing of active ulcer(s). Management of gastroesophageal reflux disease (GERD). Treatment of heartburn, acid indigestion, and sour stomach (OTC use). Management of gastric hypers ...
Treatment of Hayfever Vol 3 No 2 (PDF 46Kb)
... • Treatment in advance of the first symptoms presenting is an important aspect of management.4 ...
... • Treatment in advance of the first symptoms presenting is an important aspect of management.4 ...
2nd T. 5th L. Updated
... The t1/2 of sulindac itself is about 7 hrs, but the active sulfide has a t1/2 as long as 18 hrs. Sulindac and its metabolites undergo extensive enterohepatic circulation, and all are bound extensively to plasma protein Sulindac has been used mainly for the treatment of rheumatoid arthritis, oste ...
... The t1/2 of sulindac itself is about 7 hrs, but the active sulfide has a t1/2 as long as 18 hrs. Sulindac and its metabolites undergo extensive enterohepatic circulation, and all are bound extensively to plasma protein Sulindac has been used mainly for the treatment of rheumatoid arthritis, oste ...
baclofen
... • Tizanidine hydrochloride – alpha-2-adrenergic agent • short-acting drug for the management of spasticity. • should be reserved for those daily activities and times when relief of spasticity is most important • common adverse events make it prudent to begin treatment with single oral doses of 4 mg. ...
... • Tizanidine hydrochloride – alpha-2-adrenergic agent • short-acting drug for the management of spasticity. • should be reserved for those daily activities and times when relief of spasticity is most important • common adverse events make it prudent to begin treatment with single oral doses of 4 mg. ...
IOPIDINE® 1% IOPIDINE® 0.5% Alcon Apraclonidine HCl Controls
... anhydrase inhibitor) as part of their maximally tolerated medical therapy may not provide much additional benefit. Since apraclonidine 0.5% is an aqueous suppressing drug, the addition of a third aqueous suppressant may not significantly reduce IOP. Hypersensitivity to any component of this medicati ...
... anhydrase inhibitor) as part of their maximally tolerated medical therapy may not provide much additional benefit. Since apraclonidine 0.5% is an aqueous suppressing drug, the addition of a third aqueous suppressant may not significantly reduce IOP. Hypersensitivity to any component of this medicati ...
Second-line anti
... 65–80% of a dose is excreted unchanged in the urine over 24–48 hours, resulting in high urinary concentrations. ...
... 65–80% of a dose is excreted unchanged in the urine over 24–48 hours, resulting in high urinary concentrations. ...
Define therapeutic index and briefly outline its significance. Briefly
... toxicity) (Exception, gentamicin which has toxicity not conc-related) o Need to monitor plasma levels of drug (eg phenytoin, digoxin) Limitations: - LD50 not good guide to toxicity in humans (measured in animals)→adverse effects limiting use in clinical practice may be overlooked in animal models - ...
... toxicity) (Exception, gentamicin which has toxicity not conc-related) o Need to monitor plasma levels of drug (eg phenytoin, digoxin) Limitations: - LD50 not good guide to toxicity in humans (measured in animals)→adverse effects limiting use in clinical practice may be overlooked in animal models - ...
Anti Retro Viral Therapy
... Name Of the Drugs Zidovudine Stavudine Drugs Supplied Lamivudine By NACO at ...
... Name Of the Drugs Zidovudine Stavudine Drugs Supplied Lamivudine By NACO at ...
Joint COPD Guidelines
... – consider adding theophylline if still symptomatic Offer pulmonary rehabilitation to all suitable people Refer patients who are breathless, have a single large bulla on a CT scan and an FEV1 less than 50% predicted for consideration of bullectomy Refer people with severe COPD for consideration of l ...
... – consider adding theophylline if still symptomatic Offer pulmonary rehabilitation to all suitable people Refer patients who are breathless, have a single large bulla on a CT scan and an FEV1 less than 50% predicted for consideration of bullectomy Refer people with severe COPD for consideration of l ...
Q17 Classify the calcium channel blockers and
... function worse (because it reduces myocardial contractility). Contraindicated in patients with WPW as may cause VT/VF ...
... function worse (because it reduces myocardial contractility). Contraindicated in patients with WPW as may cause VT/VF ...
Etopan 400, 500, 600 mg XL Tablets
... Etodolac plasma concentrations, after multiple-dose administration, are slightly higher than after single doses, as predicted, indicating no change in pharmacokinetics with multiple-dose use. Etodolac is more than 99% bound to plasma proteins. Etodolac when administered orally, exhibits characterist ...
... Etodolac plasma concentrations, after multiple-dose administration, are slightly higher than after single doses, as predicted, indicating no change in pharmacokinetics with multiple-dose use. Etodolac is more than 99% bound to plasma proteins. Etodolac when administered orally, exhibits characterist ...
Drugs acting on the uterus
... Ergot alkaloids remain the drugs of choice to manage postpartum hemorrhage As compared to oxytocin, ergot alkaloids are more potent, they produce more prolonged and sustained contractions of the uterus and they are less toxic Ergot alkaloids are contraindicated to be used as inducers to delivery (a ...
... Ergot alkaloids remain the drugs of choice to manage postpartum hemorrhage As compared to oxytocin, ergot alkaloids are more potent, they produce more prolonged and sustained contractions of the uterus and they are less toxic Ergot alkaloids are contraindicated to be used as inducers to delivery (a ...
06. ANTHELMINTIC DRUGS 2006(nov 25).
... Administered orally , absorption increased with a fatty meal Metabolized in the liver to the active metabolite albendazole sulfoxide ...
... Administered orally , absorption increased with a fatty meal Metabolized in the liver to the active metabolite albendazole sulfoxide ...
ECU MFM Division Consensus Preterm labor: acute
... ii. Gestational age for administration: 23 weeks 0 days to 30 weeks 0 days ...
... ii. Gestational age for administration: 23 weeks 0 days to 30 weeks 0 days ...
Keolax Prescribing Information
... of Clobazam or in patients taking high doses of the drug. Clobazam should be used in reduced doses in patients with impaired renal or hepatic function. Side Effects Keolax is generally well tolerated. Side effects such as drowsiness or dryness of mouth have been reported. These are more likely to oc ...
... of Clobazam or in patients taking high doses of the drug. Clobazam should be used in reduced doses in patients with impaired renal or hepatic function. Side Effects Keolax is generally well tolerated. Side effects such as drowsiness or dryness of mouth have been reported. These are more likely to oc ...
Lidocaine patch
... Medications are only ONE part of a successful treatment plan. They are appropriate when they provide benefit, improve function and have either no or mild, manageable side effects. Importantly, medications (even if natural) are chemical substances not expected in the body, and as such have side eff ...
... Medications are only ONE part of a successful treatment plan. They are appropriate when they provide benefit, improve function and have either no or mild, manageable side effects. Importantly, medications (even if natural) are chemical substances not expected in the body, and as such have side eff ...
CCO Formulary Data Sheet on Androcur
... Side effects are rarely of sufficient severity to require dosage reduction or discontinuation of treatment. The most common side effects are hormonal with changes in libido, breast tenderness and gynecomastia and impotence, which are reversible. Hepatotoxicity, including liver failure has been repor ...
... Side effects are rarely of sufficient severity to require dosage reduction or discontinuation of treatment. The most common side effects are hormonal with changes in libido, breast tenderness and gynecomastia and impotence, which are reversible. Hepatotoxicity, including liver failure has been repor ...
Buprenorphine Treatment of Prescription Opiate Addiction.
... year period with lithium, Seroquel, antidepressants. Starts buprenorphine 8/07. On no psychiatric meds on admission or since. No mood disorder symptoms (which patient attributes to bup) until he stops bup 12/09. He then experienced a depressive relapse. Re-stabilizing on bup resulted in return of eu ...
... year period with lithium, Seroquel, antidepressants. Starts buprenorphine 8/07. On no psychiatric meds on admission or since. No mood disorder symptoms (which patient attributes to bup) until he stops bup 12/09. He then experienced a depressive relapse. Re-stabilizing on bup resulted in return of eu ...
Premature births, protease inhibitors and progesterone
... most did not achieve a normal weight while in the wombs of pregnant mice. It is important to bear in mind that mice in this experiment received very high concentrations (for mice) of protease inhibitors. As such, it should not be surprising that they experienced adverse reactions, both biochemically ...
... most did not achieve a normal weight while in the wombs of pregnant mice. It is important to bear in mind that mice in this experiment received very high concentrations (for mice) of protease inhibitors. As such, it should not be surprising that they experienced adverse reactions, both biochemically ...
Pharmacokinetics lecture 10
... extravascular doses Assume the same dose of a drug is administered on two occasions to the same individual. Either different dosage forms or routes of administration are used on the two occasions. ...
... extravascular doses Assume the same dose of a drug is administered on two occasions to the same individual. Either different dosage forms or routes of administration are used on the two occasions. ...
PRODUCT MONOGRAPH PROGLYCEM® Diazoxide capsules
... the litter size. In a litter of 14 from a dam having received 300 mg/kg at day 7, one offspring was found to have the ulna of the left foreleg missing arid only two toes. The ossification centers of the sternum were split and disorganized and it had an extra rib. In another reproduction study, rats ...
... the litter size. In a litter of 14 from a dam having received 300 mg/kg at day 7, one offspring was found to have the ulna of the left foreleg missing arid only two toes. The ossification centers of the sternum were split and disorganized and it had an extra rib. In another reproduction study, rats ...
Dydrogesterone
Dydrogesterone (INN, USAN, BAN), is also chemically known as 9β,10α-pregna-4,6-diene-3,20-dione. Dydrogesterone (6-dehydro-retroprogesterone) is a hormonally active, non-androgenic steroid that was developed in the 1950s.Dydrogesterone has selective progestational activity and does not inhibit ovulation. The greater rigidity of dydrogesterone also positively affects its selectivity, while natural progesterone is less selective, existing in different conformations that more easily bind to different receptors. As a consequence of its better bioavailability and the progestational activity of its main metabolites (20-, 21- and 16-hydroxy derivatives), the equivalent dose of dydrogesterone is 10–20 times lower than that of oral micronized progesterone.Dydrogesterone is used as an effective, orally active progestogen for gynaecological conditions related to a wide variety of progesterone deficiencies in pregnant women. The molecular structure and pharmacological effects are somewhat similar to endogenous progesterone, although in smaller amounts it is found to be orally active. Its freedom from hormonal effects like those related to corticoid, androgenic, estrogenic, anabolic, and other effects gives dydrogesterone an advantage over other synthesized progestogens.Dydrogesterone when used therapeutically is closely related to its physiological action on the neuro-endocrine control of ovarian function, as well as on the endometrium. This is an indication in all cases of endogeneous progesterone deficiency - relative or absolute. The molecule was licensed for use in several indications, including threatened or recurrent miscarriage, dysfunctional bleeding, infertility due to luteal insufficiency, dysmenorrhea, endometriosis, secondary amenorrhoea, irregular cycles, pre-menstrual syndrome and also as a hormone replacement therapy.Dydrogesterone has proven effective in the following conditions associated with progesterone deficiency: Infertility due to luteal insufficiency Threatened miscarriage Habitual or recurrent miscarriage. Menstrual disorders Premenstrual syndrome Endometriosis Dydrogesterone has also been registered as hormone replacement therapy (HRT) to counter-check the negative effects of unopposed estrogen on the endometrium in women with an intact uterus. Dydrogesterone is relatively safe and well tolerated, and does not exhibit the androgenic side effects that are common with some other progestins, like medroxyprogesterone acetate.