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Nephrology for Step 3
Nephrology for Step 3

... History of URI 1-2 days before presentation + Painless recurrent hematuria Recurrent hematuria following exertion Serum IgA increased in 50% of patients Normal complement Renal Biopsy to confirm Treatment: ACE inhibitor and ARB Consider adding Fish Oil Prednisone if tx-refractory or nephrotic syndro ...
Sub acute Bacterial Endocarditis Endocarditis
Sub acute Bacterial Endocarditis Endocarditis

... patients with relapsing or refractory disease. Immunosuppressive Drugs: These drugs inhibit or prevent activity of the immune system. Some drugs include cyclophosphamide, cyclosporine, azathioprine, and mycophenolate mofetil. Plasmapheresis: An important use of plasmapheresis is in the therapy that ...
Post Infectious Glomerulonephritis
Post Infectious Glomerulonephritis

... post-streptococcal glomerulonephritis (nephritogenic types).  APSGN has been shown to be nephritogenic following pharyngitis (strains 1, 3, 4, 12, 18, 25, and 49) or impetigo (strains 2, 49, 55, 57, and 60) ...
Pathophys - Renal - Systemic_vascular_hereditary
Pathophys - Renal - Systemic_vascular_hereditary

... ~Early clinical manifestation: proteinuria ~Only biopsy if: early onset renal disease, lack of retinal changes, unexplained hematuria or unusually accelerated renal impairment ~Excess ECM components ~May be related to TGF-β ...
Document
Document

... respiratory and urogenital tracts). Mucosal surfaces are the portal of entry of many pathogens. SIgA is produced excessively at mucosal surfaces and is the predominant class of Ig found in human external secretions and in tears. IgA are glycoproteins and one of five classes of Ab. Ab classes are def ...
URINARY TRACT INFECTION
URINARY TRACT INFECTION

... Drug-Induced Interstitial Nephritis ...
Nephrology Case Presentation IgA Nephropathy
Nephrology Case Presentation IgA Nephropathy

... Serum/Urine Electropheresis HBV, HCV, HIV, C3, C4, CH50 24 hour Urine: Protein, Creatinine ...
What`s hiding behind IgA nephropathy?
What`s hiding behind IgA nephropathy?

... • The link between the metabolic abnormality in Fabry´s disease and kidney tissue injury is still unclear • In females, there are highly variable levels of enzyme activity and broader range of clinical symptoms • Most females are affected; in various studies, 12% of Fabry´s patients on dialysis are ...
DOCX ENG
DOCX ENG

... clinical uncertainty, and outline ongoing clinical trials and translational studies. ...
< 1 ... 16 17 18 19 20

IgA nephropathy



IgA nephropathy (also known as IgA nephritis, IgAN, Berger disease (/bɛərˈʒeɪ/), Berger's disease, Berger's syndrome, Berger syndrome, or synpharyngitic glomerulonephritis) is a form of glomerulonephritis (inflammation of the glomeruli of the kidney).IgA nephropathy is the most common glomerulonephritis throughout the world. Primary IgA nephropathy is characterized by deposition of the IgA antibody in the glomerulus. There are other diseases associated with glomerular IgA deposits, the most common being Henoch-Schönlein purpura (HSP), which is considered by many to be a systemic form of IgA nephropathy. HSP presents with a characteristic purpuric skin rash, arthritis, and abdominal pain and occurs more commonly in young adults (16-35 yrs old). HSP is associated with a more benign prognosis than IgA nephropathy. In IgA nephropathy there is a slow progression to chronic kidney failure in 25-30% of cases during a period of 20 years.
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