Investigating the importance of anatomical homology for
... human diseases, transferring knowledge among model organisms, and studying the genetic basis of evolutionary innovations. Two organismal features, whether genes, anatomical parts, or any other inherited feature, are considered to be homologous when they are evolutionarily derived from a single featu ...
... human diseases, transferring knowledge among model organisms, and studying the genetic basis of evolutionary innovations. Two organismal features, whether genes, anatomical parts, or any other inherited feature, are considered to be homologous when they are evolutionarily derived from a single featu ...
Case of Pregnancy Favorable Outcome in a Patient
... Cervical Canal; CKD: Chronic Kidney Disease ...
... Cervical Canal; CKD: Chronic Kidney Disease ...
A disproportionate role for mtDNA in DobzhanskyMuller
... ancient endosymbiosis, in this case between a heterotrophic cell and a photosynthetic symbiont. As in the mitochondrial case, most of the proto-chloroplast genome has been transferred to the host nuclear genome; approximately 90% of the proteins required for chloroplast function are imported nuclear ...
... ancient endosymbiosis, in this case between a heterotrophic cell and a photosynthetic symbiont. As in the mitochondrial case, most of the proto-chloroplast genome has been transferred to the host nuclear genome; approximately 90% of the proteins required for chloroplast function are imported nuclear ...
Ribosomal Protein RPL27a Promotes Female
... (Fig. 2C). The frequency of defective ovules in rpl27ab mutants was higher than the wild type but less than that in rpl27ac mutants. Given that RPL27aC and RPL27aB acted redundantly in leaf development, we examined whether these genes are redundant in ovule development by testing whether RPL27aB can ...
... (Fig. 2C). The frequency of defective ovules in rpl27ab mutants was higher than the wild type but less than that in rpl27ac mutants. Given that RPL27aC and RPL27aB acted redundantly in leaf development, we examined whether these genes are redundant in ovule development by testing whether RPL27aB can ...
Ragdoll
... veterinary hospital at the University of California. Josephine was of a Persian/Angora type and had litters sired by several unknown male Birman or Burmese-like cats, one of which had the Siamese point coloration. After Josephine recovered, her next litter produced kittens with a docile, placid temp ...
... veterinary hospital at the University of California. Josephine was of a Persian/Angora type and had litters sired by several unknown male Birman or Burmese-like cats, one of which had the Siamese point coloration. After Josephine recovered, her next litter produced kittens with a docile, placid temp ...
X chromosome inactivation failed to explain normal phenotype Clin
... her first seizures characterized by tonic movement of the upper limbs and loss of consciousness. At that time, electroencephalography and brain magnetic resonance imaging did not reveal any abnormalities. Thus, she was diagnosed with Rett syndrome, which was further confirmed by a mutation in the ME ...
... her first seizures characterized by tonic movement of the upper limbs and loss of consciousness. At that time, electroencephalography and brain magnetic resonance imaging did not reveal any abnormalities. Thus, she was diagnosed with Rett syndrome, which was further confirmed by a mutation in the ME ...
Making Genetics Easy and Fun - California Science Teachers
... • Determine evolutionary relationships (phylogenetics) within and between species • Turn genes up (upregulation) and down (down regulation), or on (gene activation) and off (gene silencing) • Grow cells (cell culture), manipulate stem cells to develop into specific tissue types (differentiation), or ...
... • Determine evolutionary relationships (phylogenetics) within and between species • Turn genes up (upregulation) and down (down regulation), or on (gene activation) and off (gene silencing) • Grow cells (cell culture), manipulate stem cells to develop into specific tissue types (differentiation), or ...
FEMS Microbiology Letters
... (pACYC-ChrBAC). The bars of SD are shown (n = 4). (b) Pseudomonas aeruginosa, (&) PAO1 (pUCP20), (n) PAO1 (pUCP20-ChrA), (’) PAO1-ChrR and (m) PAO1-ChrR (pUCP20-ChrA). Percentage of growth is shown because the strains displayed different levels of growth. The bars of SD are shown (n = 8). ...
... (pACYC-ChrBAC). The bars of SD are shown (n = 4). (b) Pseudomonas aeruginosa, (&) PAO1 (pUCP20), (n) PAO1 (pUCP20-ChrA), (’) PAO1-ChrR and (m) PAO1-ChrR (pUCP20-ChrA). Percentage of growth is shown because the strains displayed different levels of growth. The bars of SD are shown (n = 8). ...
Two novel heterozygous mutations of EVC2 cause a mild phenotype
... A considerable number of EvC cases have already been screened for mutations, including the systematic screening of 65 EvC cases in which all coding exons of both genes were sequenced [Tompson et al., 2007]. With the exception of two families reported by Temtamy et al. [2008], all EvC patients screen ...
... A considerable number of EvC cases have already been screened for mutations, including the systematic screening of 65 EvC cases in which all coding exons of both genes were sequenced [Tompson et al., 2007]. With the exception of two families reported by Temtamy et al. [2008], all EvC patients screen ...
PCDH19-related Infantile Epileptic Encephalopathy - HAL
... at the tissue level because of abnormal interactions between “mutated” and “normal” cells. A mechanism of this type was termed “cellular interference” [Wieland et al., 2004] in reference to the “metabolic interference” concept developed many years ago by William Johnson [Johnson, 1980]. According to ...
... at the tissue level because of abnormal interactions between “mutated” and “normal” cells. A mechanism of this type was termed “cellular interference” [Wieland et al., 2004] in reference to the “metabolic interference” concept developed many years ago by William Johnson [Johnson, 1980]. According to ...
Volume 46 - Tomato Genetics Cooperative
... Cf-4, Ontario 7522 and Ontario 7715 were identical and different from control lines. In experiments using PCR primers derived from the DNA sequence of Cf-9 no difference in PCR pattern between MM Cf-4, Ontario 7522 and Ontario 7716 was detected again. Later, specific PCR primers were designed, based ...
... Cf-4, Ontario 7522 and Ontario 7715 were identical and different from control lines. In experiments using PCR primers derived from the DNA sequence of Cf-9 no difference in PCR pattern between MM Cf-4, Ontario 7522 and Ontario 7716 was detected again. Later, specific PCR primers were designed, based ...
Human Genetic Variation Databases Workshop - Cordis
... strategy for achieving this has been formulated. Existing collections of genetic relationships, predominantly from Mendelian single gene variation traits, when supplemented by information from model organisms, have provided many fundamental insights into human biology, at both the body and cellular ...
... strategy for achieving this has been formulated. Existing collections of genetic relationships, predominantly from Mendelian single gene variation traits, when supplemented by information from model organisms, have provided many fundamental insights into human biology, at both the body and cellular ...
Tandem Genetic Duplications in Phage and Bacteria
... earlier, the only novel base sequence in chromosomes carrying a duplication is the join point between copies of the duplicated segment. At this point, sequences that would be widely separated in a normal chromosome are made contiguous. Trans duction of this join point from a donor harboring a dupli ...
... earlier, the only novel base sequence in chromosomes carrying a duplication is the join point between copies of the duplicated segment. At this point, sequences that would be widely separated in a normal chromosome are made contiguous. Trans duction of this join point from a donor harboring a dupli ...
LIST OF CHECK-UP QUESTIONS for
... 7. What type of mutations has the greatest probability to be expressed in the next generation? a) recessive, linked with a sex, which arises in X-chromosome; b) recessive, which arises in autosomes; c) dominant autosomal mutation CORRECT d) all of these avove 8. A human has galactosemia — a disease ...
... 7. What type of mutations has the greatest probability to be expressed in the next generation? a) recessive, linked with a sex, which arises in X-chromosome; b) recessive, which arises in autosomes; c) dominant autosomal mutation CORRECT d) all of these avove 8. A human has galactosemia — a disease ...
An Introduction to Genetic Analysis Chapter 24 Population Genetics
... factor, determining whether the M and N proteins are also contained in the saliva) is closely linked to the M N locus in humans. Table 24-2 shows the frequencies, commonly symbolized by g's, of the four haplotypes (M S, M s, N S, and N s) in various populations. First, we can calculate the frequency ...
... factor, determining whether the M and N proteins are also contained in the saliva) is closely linked to the M N locus in humans. Table 24-2 shows the frequencies, commonly symbolized by g's, of the four haplotypes (M S, M s, N S, and N s) in various populations. First, we can calculate the frequency ...
Control of the proliferation versus meiotic development decision in
... the differentiation pathway the stem cell population is depleted and only a small number of the differentiated cells are made. Conversely, if stem cells continue to proliferate and fail to enter a differentiation pathway, tissue homeostasis is not maintained and a tumor may result. The need for cont ...
... the differentiation pathway the stem cell population is depleted and only a small number of the differentiated cells are made. Conversely, if stem cells continue to proliferate and fail to enter a differentiation pathway, tissue homeostasis is not maintained and a tumor may result. The need for cont ...
A Conserved Molecular Framework for Compound Leaf Development
... meristem Cardamine hirsuta RNA using the Arabidopsis-based primers RLT-FwdAT5G53950 and CUC2 3' and insitu CUC3 L Fwd insitu CUC3 L Rv+T7, respectively. A fragment of ChCUC1 was amplified using the degenerated primers NACdegFw2 and ...
... meristem Cardamine hirsuta RNA using the Arabidopsis-based primers RLT-FwdAT5G53950 and CUC2 3' and insitu CUC3 L Fwd insitu CUC3 L Rv+T7, respectively. A fragment of ChCUC1 was amplified using the degenerated primers NACdegFw2 and ...
Detection and analysis of disease-associated single nucleotide
... experimental phosphorylation binding sites and found 1,515 coding-region SNPs in the flanking phosphorylation binding sites with position -7 to +7. Ryu et al. [10] collected 33,651 protein-sequence variations from the SwissVariant database and predicted the effects of variants on phosphorylation bin ...
... experimental phosphorylation binding sites and found 1,515 coding-region SNPs in the flanking phosphorylation binding sites with position -7 to +7. Ryu et al. [10] collected 33,651 protein-sequence variations from the SwissVariant database and predicted the effects of variants on phosphorylation bin ...
CHAPTER 3 ORGANIC CHEMISTRY
... Some traits have more than two possible alleles for a single trait. Each person can only have two alleles for a given trait because diploid organisms have only 2 copies of each gene. ...
... Some traits have more than two possible alleles for a single trait. Each person can only have two alleles for a given trait because diploid organisms have only 2 copies of each gene. ...
cbb752-mg-spr10-bioinfo-intro
... What is Bioinformatics? • One idea for a definition? Bioinformatics is conceptualizing biology in terms of molecules (in the sense of physical-chemistry) and then applying “informatics” techniques (derived from disciplines such as applied math, CS, and statistics) to understand and organize the inf ...
... What is Bioinformatics? • One idea for a definition? Bioinformatics is conceptualizing biology in terms of molecules (in the sense of physical-chemistry) and then applying “informatics” techniques (derived from disciplines such as applied math, CS, and statistics) to understand and organize the inf ...
Mutations affecting craniofacial development in zebrafish
... Genetic analysis Genetic segregation of individual mutations was determined by assessing on average 1000 embryos from crosses of heterozygous parents for any given mutation. In order to test potential allelism of isolated mutations, complementation testing among members of the phenotypically defined ...
... Genetic analysis Genetic segregation of individual mutations was determined by assessing on average 1000 embryos from crosses of heterozygous parents for any given mutation. In order to test potential allelism of isolated mutations, complementation testing among members of the phenotypically defined ...
P generation
... Multiple Alleles • Most genes exist in populations in more than two allelic forms ...
... Multiple Alleles • Most genes exist in populations in more than two allelic forms ...
The RNA world meets behavior: AfiI pre
... Fig. 1. Sites of Afi I pre-mRNA editing in mammals (a) and Drosophila (b). Circles represent editing sites that are at unique coding positions (green) or are in identical coding positions between paralogous genes (red). Note that one editing site (Q/R) is shared between more distant relatives of the ...
... Fig. 1. Sites of Afi I pre-mRNA editing in mammals (a) and Drosophila (b). Circles represent editing sites that are at unique coding positions (green) or are in identical coding positions between paralogous genes (red). Note that one editing site (Q/R) is shared between more distant relatives of the ...
Control of GL2 expression in Arabidopsis leaves and trichomes
... developing leaves, and is localized in the nucleus in developing trichomes Both GL1 and TTG may directly bind to the GL2 promoter, either alone or as part of a larger complex, but the interaction between GL1 and R somehow eliminates the requirement for TTG – Further studies [Since 1998] of the mecha ...
... developing leaves, and is localized in the nucleus in developing trichomes Both GL1 and TTG may directly bind to the GL2 promoter, either alone or as part of a larger complex, but the interaction between GL1 and R somehow eliminates the requirement for TTG – Further studies [Since 1998] of the mecha ...