Antigenic diversity of Theileria major piroplasm surface protein gene
... The major clinical sign of bovine piroplasmosis is hemolytic anemia, but this sign may not be obvious in herds with subclinical infections [20]. A combination of predisposing factors influences the course of the clinical illness. Although we found piroplasms in nine cows on microscopic examination, ...
... The major clinical sign of bovine piroplasmosis is hemolytic anemia, but this sign may not be obvious in herds with subclinical infections [20]. A combination of predisposing factors influences the course of the clinical illness. Although we found piroplasms in nine cows on microscopic examination, ...
Genetic algorithms with multi-parent recombination
... We have tested five numerical functions to be optimized and two 'real' problems. For numerical optimization we have chosen four well-known DeJong functions (the formulas were taken from [Go189]) and a function from [Mic92] because these functions provide a test-bench with variously shaped functions. ...
... We have tested five numerical functions to be optimized and two 'real' problems. For numerical optimization we have chosen four well-known DeJong functions (the formulas were taken from [Go189]) and a function from [Mic92] because these functions provide a test-bench with variously shaped functions. ...
Bowel Cancer and Inherited Predisposition
... to be a combination of genetic factors, environmental factors and the process of ageing. Research is currently being undertaken to more fully understand the cause of specific gene mutations. For the small number of people that have inherited a mutation in a ‘cancer protection’ gene the division and ...
... to be a combination of genetic factors, environmental factors and the process of ageing. Research is currently being undertaken to more fully understand the cause of specific gene mutations. For the small number of people that have inherited a mutation in a ‘cancer protection’ gene the division and ...
Dominant and recessive central core disease associated with
... When muscle samples were unavailable, RYR1 mutation screening was performed on genomic DNA extracted from blood samples using standard procedures. Exons 92±106 coding for the calcium channel domain and exons involved in the MH1 and MH2 domains were analysed by denaturating ...
... When muscle samples were unavailable, RYR1 mutation screening was performed on genomic DNA extracted from blood samples using standard procedures. Exons 92±106 coding for the calcium channel domain and exons involved in the MH1 and MH2 domains were analysed by denaturating ...
Genetic Algorithms: Genetic Algorithm Applications to Actuarial Problems ARC 2012
... Dave Snell, ASA, MAAA, CLU, ChFC, FLMI, MCP, ARA, ACS Technology Evangelist, Vice Chairman’s Office ...
... Dave Snell, ASA, MAAA, CLU, ChFC, FLMI, MCP, ARA, ACS Technology Evangelist, Vice Chairman’s Office ...
Chapter 23 PowerPoint 2016 - Spring
... produce the genetic variation that makes evolution possible • 2 processes produce variation in gene pools that contributes to differences among individuals = mutation and sexual reproduction – Variation in individual genotype leads to variation in individual phenotype – Not all phenotypic variation ...
... produce the genetic variation that makes evolution possible • 2 processes produce variation in gene pools that contributes to differences among individuals = mutation and sexual reproduction – Variation in individual genotype leads to variation in individual phenotype – Not all phenotypic variation ...
Case Report Novel Sonic Hedgehog Mutation in a Couple
... mutation found in this case is at position 127 (TGG for TGA), which suggests that mutations in this adjacent residues are associated with an important phenotypic clinical variability. The etiology of the wide phenotypic spectrum is not yet understood, and it has been proposed that other genes or env ...
... mutation found in this case is at position 127 (TGG for TGA), which suggests that mutations in this adjacent residues are associated with an important phenotypic clinical variability. The etiology of the wide phenotypic spectrum is not yet understood, and it has been proposed that other genes or env ...
one in three hundred sixty thousand
... That leads to constant breaking of DNA strands, something most people fix well, but not Fanconi patients. Normal Fanconi genes help find and fix crosslinked DNA. Intriguingly, these genes somehow interact with BRCA1, a gene that, when mutated, predisposes carriers to breast cancer. BRCA2, a related ...
... That leads to constant breaking of DNA strands, something most people fix well, but not Fanconi patients. Normal Fanconi genes help find and fix crosslinked DNA. Intriguingly, these genes somehow interact with BRCA1, a gene that, when mutated, predisposes carriers to breast cancer. BRCA2, a related ...
Evolutionary implications of non- neutral
... for the nuclear background. One simple way to screen for potential mitochondrial genetic effects is to conduct reciprocal crosses between two populations. The resulting daughters of each cross will then share an identical set of possible nuclear backgrounds but will have mtDNA that is derived from t ...
... for the nuclear background. One simple way to screen for potential mitochondrial genetic effects is to conduct reciprocal crosses between two populations. The resulting daughters of each cross will then share an identical set of possible nuclear backgrounds but will have mtDNA that is derived from t ...
Mechanisms and impact of genetic recombination in the evolution of
... serotypes has been reported both in terms of the invasive disease potential [14] and global geographical distribution [15]. Pneumococcal Conjugate Vaccines (PCVs) that target the pneumococcal capsule offer protection against the serotypes most commonly associated with invasive disease. PCV7 consists ...
... serotypes has been reported both in terms of the invasive disease potential [14] and global geographical distribution [15]. Pneumococcal Conjugate Vaccines (PCVs) that target the pneumococcal capsule offer protection against the serotypes most commonly associated with invasive disease. PCV7 consists ...
E-Halliburton chapter 1
... 2. Effect of deviation from the assumption of no mutation Point mutations (basepair changes which cause amino acid substitutions) are the real source of genetic variation, and the raw material of evolution. They occur randomly but with an average frequency which appears to vary between loci. However ...
... 2. Effect of deviation from the assumption of no mutation Point mutations (basepair changes which cause amino acid substitutions) are the real source of genetic variation, and the raw material of evolution. They occur randomly but with an average frequency which appears to vary between loci. However ...
Imprinting and Seed Development
... The parental conflict theory can explain many, but not all, of the seed phenotypes observed in reciprocal crosses. Maize endosperm (2m:2p) resulting from the cross between a diploid female and its autotetraploid male causes kernel abortion 10 to 12 days after pollination (DAP) (Lin, 1984). Phenotypi ...
... The parental conflict theory can explain many, but not all, of the seed phenotypes observed in reciprocal crosses. Maize endosperm (2m:2p) resulting from the cross between a diploid female and its autotetraploid male causes kernel abortion 10 to 12 days after pollination (DAP) (Lin, 1984). Phenotypi ...
Aetiopathogenesis and Treatment of Vitiligo
... survive detachment by trypsinization, while melanocytes from normal humans survive many such detachments from culture dishes." The melanocytes from perilesional areas of untreated vitiligo patients do not grow at all in culture and show an abnormal morphology compared to cells from an uninvolved are ...
... survive detachment by trypsinization, while melanocytes from normal humans survive many such detachments from culture dishes." The melanocytes from perilesional areas of untreated vitiligo patients do not grow at all in culture and show an abnormal morphology compared to cells from an uninvolved are ...
EMBL-EBI Powerpoint Presentation
... • How many paralogues have been identified for the G6PD1 gene? Which paralogues show the highest sequence similarity? • Does the plant gene tree reflect the information that is shown on the ‘Paralogues’ page? • Does the pan-taxonomic gene tree confirm that glucose-6-phosphate dehydrogenase is presen ...
... • How many paralogues have been identified for the G6PD1 gene? Which paralogues show the highest sequence similarity? • Does the plant gene tree reflect the information that is shown on the ‘Paralogues’ page? • Does the pan-taxonomic gene tree confirm that glucose-6-phosphate dehydrogenase is presen ...
巴西橡胶Pto类抗病同源序列的克隆与系统发育重建
... related to Pto-RGCs from other plant species than each other. Another interesting finding was that the clades where the hevea Pto-RGCs were grouped (I, II and III) also contain Pto-RGCs from different species, suggesting that the origin of ...
... related to Pto-RGCs from other plant species than each other. Another interesting finding was that the clades where the hevea Pto-RGCs were grouped (I, II and III) also contain Pto-RGCs from different species, suggesting that the origin of ...
Temperature-sensitive control of protein activity by conditionally
... Our ability to understand gene functions largely relies on methods that allow the precise control of gene expression and the activity of their products. The use of temperature-sensitive alleles is a wellestablished method that is applicable to any organism upon which temperature changes can be impos ...
... Our ability to understand gene functions largely relies on methods that allow the precise control of gene expression and the activity of their products. The use of temperature-sensitive alleles is a wellestablished method that is applicable to any organism upon which temperature changes can be impos ...
THE EVOLUTION OF SELECTIVE ADVANTAGE IN A
... variable. It may therefore be interesting to see the results of selection for a deleterious mutation with different initial variances in the fitness of its heterozygote. The selective coefficients at the start of selection were for the genotype AA, 0.5; for Aa, 0.6; and for aa, 0.7. These selective ...
... variable. It may therefore be interesting to see the results of selection for a deleterious mutation with different initial variances in the fitness of its heterozygote. The selective coefficients at the start of selection were for the genotype AA, 0.5; for Aa, 0.6; and for aa, 0.7. These selective ...
Introductory genetics for veterinary students
... A note on F2 vs line-cross models Is it reasonable to assume that the Q and q alleles will be alternatively “fixed” in the alternate F0 lines? Hence, that the QTL genotype of all F1 animals is the same? Especially when this is not the case for the SNP or microsatellite markers. This has lead to ...
... A note on F2 vs line-cross models Is it reasonable to assume that the Q and q alleles will be alternatively “fixed” in the alternate F0 lines? Hence, that the QTL genotype of all F1 animals is the same? Especially when this is not the case for the SNP or microsatellite markers. This has lead to ...
Presentazione di PowerPoint
... Mendel’s laws apply to humans Genetic pedigrees can reveal the patterns of inheritance. How to create a pedigree ...
... Mendel’s laws apply to humans Genetic pedigrees can reveal the patterns of inheritance. How to create a pedigree ...
Antisense Transcript and RNA Processing
... was required for viability but could not produce stable atpB transcripts. Based on strand-specific RT-PCR, S1 nuclease protection, and RNA gel blots, evidence was obtained that the PSþ genome stabilizes atpB mRNA by generating an atpB antisense transcript, which attenuates the degradation of the pol ...
... was required for viability but could not produce stable atpB transcripts. Based on strand-specific RT-PCR, S1 nuclease protection, and RNA gel blots, evidence was obtained that the PSþ genome stabilizes atpB mRNA by generating an atpB antisense transcript, which attenuates the degradation of the pol ...
PDF
... polymorphism in traits influencing survival and reproduction. Examples include cheatercooperator polymorphism and polymorphic microbial pathogens. Environmental heterogeneity, favoring different traits in nearby habitats, with dispersal between them, is one general reason to expect polymorphism. Cur ...
... polymorphism in traits influencing survival and reproduction. Examples include cheatercooperator polymorphism and polymorphic microbial pathogens. Environmental heterogeneity, favoring different traits in nearby habitats, with dispersal between them, is one general reason to expect polymorphism. Cur ...
Statistical power and significance testing in large
... The classical approach to hypothesis testing developed by Neyman and Pearson2 involves setting up a null hypothesis (H0) and an alternative hypothesis (H1), calculating a test statistic (T) from the observed data and then deciding on the basis of T whether to reject H0. In genetic studies, H0 typica ...
... The classical approach to hypothesis testing developed by Neyman and Pearson2 involves setting up a null hypothesis (H0) and an alternative hypothesis (H1), calculating a test statistic (T) from the observed data and then deciding on the basis of T whether to reject H0. In genetic studies, H0 typica ...
Disease and Trait Information for IDB Genotyped Animals in
... Figure 2: This image shows what happens in an animal produced from a sire and dam with different allele types for one gene. The dam has contributed a normal (red) allele while the male contributed a diseased (blue) allele to the offspring. This results in the offspring being a carrier of the disease ...
... Figure 2: This image shows what happens in an animal produced from a sire and dam with different allele types for one gene. The dam has contributed a normal (red) allele while the male contributed a diseased (blue) allele to the offspring. This results in the offspring being a carrier of the disease ...
mgm1, the earliest sex-specific germline marker in Drosophila
... Somatic follicle cells also undergo some rounds of endoreplication (Calvi et al., 1998). To test whether ectopic esg expression prevents endoreplication either in nurse cells or in follicle cells in female gonads, we analyzed females carrying a hs::esg construct (a kind gift from S. Hayashi) that we ...
... Somatic follicle cells also undergo some rounds of endoreplication (Calvi et al., 1998). To test whether ectopic esg expression prevents endoreplication either in nurse cells or in follicle cells in female gonads, we analyzed females carrying a hs::esg construct (a kind gift from S. Hayashi) that we ...
Overexpression of Rice OSH Genes Induces Ectopic
... OSH10, OSH15, OSH43, and OSH71 (Sentoku et al., 1999). When the homeobox gene OSH1 was overexpressed in transgenic rice plants under the control of the 35S promoter, unique phenotypic alterations in leaf structure, ligule displacement, and loss of the pair of auricles were observed (Matsuoka et al., ...
... OSH10, OSH15, OSH43, and OSH71 (Sentoku et al., 1999). When the homeobox gene OSH1 was overexpressed in transgenic rice plants under the control of the 35S promoter, unique phenotypic alterations in leaf structure, ligule displacement, and loss of the pair of auricles were observed (Matsuoka et al., ...