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... tively. We find that the accuracy of FirstEF is significantly higher for CpG-related than non-CpG-related genes. To study the performance of FirstEF on the genome scale, we ran it on human chromosomes 21 and 22 and compared the predictions with the experimentally chromosomes 21 and 22. We downloaded ...
... tively. We find that the accuracy of FirstEF is significantly higher for CpG-related than non-CpG-related genes. To study the performance of FirstEF on the genome scale, we ran it on human chromosomes 21 and 22 and compared the predictions with the experimentally chromosomes 21 and 22. We downloaded ...
Functional Analysis of Genes Implicated in Down Syndrome: 2
... classified as left-handed (1) if they stated that they wrote with their left hand; (2) if they used their left hand more frequently for the majority of the six primary handedness items in Annett’s questionnaire; or (3) if they used their left hand more frequently in the majority of an extended 11-ite ...
... classified as left-handed (1) if they stated that they wrote with their left hand; (2) if they used their left hand more frequently for the majority of the six primary handedness items in Annett’s questionnaire; or (3) if they used their left hand more frequently in the majority of an extended 11-ite ...
THE EFFECTS OF GENOTYPE AND CELL
... harderian glands, and in the nictitans, choroid, and retina of the eye. For the present investigation attention was centered on six tissues: hair bulbs, ear skin, harderian gland, nictitans, retina, and choroid. I n many mouse genotypes these six tissues are abundantly supplied with melanocytes, and ...
... harderian glands, and in the nictitans, choroid, and retina of the eye. For the present investigation attention was centered on six tissues: hair bulbs, ear skin, harderian gland, nictitans, retina, and choroid. I n many mouse genotypes these six tissues are abundantly supplied with melanocytes, and ...
Liver Effects of Clinical Drugs Differentiated in Human Liver
... extent of injury and number of hits [23,24]. Human liver slices cultured for several days exhibit the activation of endothelial cells, Kupffer cells, stellate cells and repair pathways [25,26]. Advancements in the culturing of human liver slices to extend the viability of human liver slices to sever ...
... extent of injury and number of hits [23,24]. Human liver slices cultured for several days exhibit the activation of endothelial cells, Kupffer cells, stellate cells and repair pathways [25,26]. Advancements in the culturing of human liver slices to extend the viability of human liver slices to sever ...
The Role of Melanocortin-1 Receptor Polymorphism in Skin Cancer
... place individuals at a higher risk of skin cancer [reviewed in (14)]. To quantify the relative contribution of each independent MC1R variant allele to pigmentary phenotypes associated with high skin cancer risk, we have examined statistical associations of some common MC1R gene variants with red hai ...
... place individuals at a higher risk of skin cancer [reviewed in (14)]. To quantify the relative contribution of each independent MC1R variant allele to pigmentary phenotypes associated with high skin cancer risk, we have examined statistical associations of some common MC1R gene variants with red hai ...
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... based on the standard culture of bacteria in the presence of an antibiotic. These indicate susceptibility to different antibiotic classes and can be used to direct therapy, but are slow and take up to 72 h. In the absence of rapid results, treatment will often use broad-spectrum antibiotics on an em ...
... based on the standard culture of bacteria in the presence of an antibiotic. These indicate susceptibility to different antibiotic classes and can be used to direct therapy, but are slow and take up to 72 h. In the absence of rapid results, treatment will often use broad-spectrum antibiotics on an em ...
Title Changes in the Concept of "Fitness" in Evolutionary Biology
... interchangeable with "adapted" and "adaptation." What is the difference between "adaptation" and "fitness"? According to Burian, "adaptation" has two primary meanings in evolutionary context: one is "transgenerational alterations of the features and capacities of organisms" that enable the organism ...
... interchangeable with "adapted" and "adaptation." What is the difference between "adaptation" and "fitness"? According to Burian, "adaptation" has two primary meanings in evolutionary context: one is "transgenerational alterations of the features and capacities of organisms" that enable the organism ...
Isolation, Characterization, and Annotation: The Search for Novel
... phages are not living, but they contain genetic material. Upon encountering a host bacterium, a phage attaches to the host, penetrates the cell membrane and injects its DNA. The genetic information can then follow two potential paths. In the lysogenic cycle, the DNA is incorporated into the host gen ...
... phages are not living, but they contain genetic material. Upon encountering a host bacterium, a phage attaches to the host, penetrates the cell membrane and injects its DNA. The genetic information can then follow two potential paths. In the lysogenic cycle, the DNA is incorporated into the host gen ...
Gene regulation in three dimensions
... Last, but not least I would like to thank Julie my fiancé who has supported me and been there for me when I needed it the most. K.T.W ...
... Last, but not least I would like to thank Julie my fiancé who has supported me and been there for me when I needed it the most. K.T.W ...
Finding New Clock Components: Past and Future
... knockout is Per2, which causes a 1.5-h period shortening and eventual loss of rhythms in the majority of mice in constant darkness (Zheng et al., 1999). Knockouts of Per1 and Per3 fall into the subtle (0-1 hour period changes) category at best (Bae et al., 2001). Fortunately, the Per1/Per2 double-kn ...
... knockout is Per2, which causes a 1.5-h period shortening and eventual loss of rhythms in the majority of mice in constant darkness (Zheng et al., 1999). Knockouts of Per1 and Per3 fall into the subtle (0-1 hour period changes) category at best (Bae et al., 2001). Fortunately, the Per1/Per2 double-kn ...
Congratulations!
... PCA Analysis of Eevee’s DNA sample and samples of Beagle and Shih Tzu from the Wisdom Panel database: Principle Component Analysis (PCA) allows us to see how similar samples are. Closely related samples, like dogs from the same breed, will be expected to be closer together than samples from other br ...
... PCA Analysis of Eevee’s DNA sample and samples of Beagle and Shih Tzu from the Wisdom Panel database: Principle Component Analysis (PCA) allows us to see how similar samples are. Closely related samples, like dogs from the same breed, will be expected to be closer together than samples from other br ...
2008 HSC Notes from the Marking Centre Biology
... question and plan responses carefully, working within that framework to produce a clear and concise response. The the use of dot points, diagrams and/or tables may help avoid internal contradictions. This is particularly important in holistic questions that need to be logical and well structured. Be ...
... question and plan responses carefully, working within that framework to produce a clear and concise response. The the use of dot points, diagrams and/or tables may help avoid internal contradictions. This is particularly important in holistic questions that need to be logical and well structured. Be ...
Development and characterization of DehaloR^2, a novel anaerobic
... to H2 and acetate, two metabolites representing, respectively, the required electron donor and carbon source for Dehalococcoides. The bacteria responsible for fermentation include at least one species of homoacetogens of the genera Sporomusa, Spirochaetes, or Acetobacterium, believed to provide Deha ...
... to H2 and acetate, two metabolites representing, respectively, the required electron donor and carbon source for Dehalococcoides. The bacteria responsible for fermentation include at least one species of homoacetogens of the genera Sporomusa, Spirochaetes, or Acetobacterium, believed to provide Deha ...
HLA matching, compatibility testing and donor selection
... Medium resolution typing implies that a DNA based test has been used, but it not discriminatory enough to tell us the exact allele i.e. it can define specific allele groups (often as a ‘string’ of possible alleles). For example an HLA-A*0201 allele may be typed as an A*0201/0205/0209/0240 with the t ...
... Medium resolution typing implies that a DNA based test has been used, but it not discriminatory enough to tell us the exact allele i.e. it can define specific allele groups (often as a ‘string’ of possible alleles). For example an HLA-A*0201 allele may be typed as an A*0201/0205/0209/0240 with the t ...
Single-copy nuclear genes resolve the phylogeny of the
... 18S findings implied that a homeotic mutation, similar to those documented in laboratory studies with the ultrabithorax gene (Ubx) in Drosophila melanogaster [25], could have been responsible for the differing wing arrangement found in the two orders [21]; however, no supporting genetic evidence for ...
... 18S findings implied that a homeotic mutation, similar to those documented in laboratory studies with the ultrabithorax gene (Ubx) in Drosophila melanogaster [25], could have been responsible for the differing wing arrangement found in the two orders [21]; however, no supporting genetic evidence for ...
Rolling circle transcription on smallest size double stranded DNA
... While DNA is much more stable than its twin RNA owing to the absence of the latter’s ribose 2’ Hydroxyl group it is still very much affected by its surroundings. The major modes of damage to hydrolysed DNA are depurination of the sugar base, deamination of the base itself and general oxidative proce ...
... While DNA is much more stable than its twin RNA owing to the absence of the latter’s ribose 2’ Hydroxyl group it is still very much affected by its surroundings. The major modes of damage to hydrolysed DNA are depurination of the sugar base, deamination of the base itself and general oxidative proce ...
Synapsis-Mediated Fusion of Free DNA Ends Forms Inverted Dimer Plasmids in Yeast.
... the plasmid do not share homology with the yeast genome, circular inverted (head-to-head) dimer plasmids are theprincipal product of repair. By measurements of the DNA concentration dependence of transformation with alinearized plasmid, and by transformation with mixtures of genetically marked plasm ...
... the plasmid do not share homology with the yeast genome, circular inverted (head-to-head) dimer plasmids are theprincipal product of repair. By measurements of the DNA concentration dependence of transformation with alinearized plasmid, and by transformation with mixtures of genetically marked plasm ...
Mosaic: A Position-Effect Variegation Eye
... Since elevated culture temperature is known to suppress PEV, Mos expression was determined when larvae were reared at temperatures at the low and high end of the reasonable laboratory rearing temperature range; either 228C or 328C. Culturing pure-breeding Mos pw at 328C beginning 24 h before hatchin ...
... Since elevated culture temperature is known to suppress PEV, Mos expression was determined when larvae were reared at temperatures at the low and high end of the reasonable laboratory rearing temperature range; either 228C or 328C. Culturing pure-breeding Mos pw at 328C beginning 24 h before hatchin ...
Altered cellular proliferation and mesoderm
... 2 week period. For activation assay, splenocytes were seeded at a concentration of 106 cells/ml in a 96-well plate. Cells were incubated in 200 µl of DME, 10% FCS, 10 mM Hepes pH 7.4 solution supplemented with 10 µg/ml of LypoPolySaccharide (LPS, Sigma). After 48 hours of incubation at 37°C, [3H]thy ...
... 2 week period. For activation assay, splenocytes were seeded at a concentration of 106 cells/ml in a 96-well plate. Cells were incubated in 200 µl of DME, 10% FCS, 10 mM Hepes pH 7.4 solution supplemented with 10 µg/ml of LypoPolySaccharide (LPS, Sigma). After 48 hours of incubation at 37°C, [3H]thy ...
slides - Referent Tracking Unit
... What are genes? • There is not much consensus of opinion among geneticists as to what genes are — whether they are real or purely fictitious — because at the level at which the genetic experiments lie, it does not make the slightest difference whether the gene is a hypothetical unit, or whether the ...
... What are genes? • There is not much consensus of opinion among geneticists as to what genes are — whether they are real or purely fictitious — because at the level at which the genetic experiments lie, it does not make the slightest difference whether the gene is a hypothetical unit, or whether the ...
TP53 mutations as biomarkers for cancer epidemiology in Latin
... America, however, a number of cancers that arise are uncommon in Northern America, in particular cancers of the stomach and oesophagus (squamous cell), as well as pancreas and leukemia in Central America. In women, the difference between Northern and Latin America is even more striking. Cervical can ...
... America, however, a number of cancers that arise are uncommon in Northern America, in particular cancers of the stomach and oesophagus (squamous cell), as well as pancreas and leukemia in Central America. In women, the difference between Northern and Latin America is even more striking. Cervical can ...