Supplementary Methods S2: Exome Sequencing
									
... The sequencing data‐ processing pipeline, called “Picard” (http://picard.sourceforge.net/; Fennel T. et al., unpublished), developed by the Sequencing Platform at the Broad Institute, starts with the reads and qualities produced by the Illumina software for all lanes and libraries generated for a si ...
                        	... The sequencing data‐ processing pipeline, called “Picard” (http://picard.sourceforge.net/; Fennel T. et al., unpublished), developed by the Sequencing Platform at the Broad Institute, starts with the reads and qualities produced by the Illumina software for all lanes and libraries generated for a si ...
									Bayesian regularization of non-homogeneous dynamic Bayesian
									
... gene 1 and gene 3 co-regulate gene 2 Remark: In gene regulatory networks the protein level is ignored. That is, proteins may build complexes with each other or may have to be activated (e.g. phosphorylated) before they can bind to binding sites of genes. ...
                        	... gene 1 and gene 3 co-regulate gene 2 Remark: In gene regulatory networks the protein level is ignored. That is, proteins may build complexes with each other or may have to be activated (e.g. phosphorylated) before they can bind to binding sites of genes. ...
									chapter 15
									
...  Sturtevant used the testcross design to map the relative position of three fruit fly genes, body color (b), wing size (vg), and eye color (cn).  The recombination frequency between cn and b is 9%.  The recombination frequency between cn and vg is 9.5%.  The recombination frequency between b and ...
                        	...  Sturtevant used the testcross design to map the relative position of three fruit fly genes, body color (b), wing size (vg), and eye color (cn).  The recombination frequency between cn and b is 9%.  The recombination frequency between cn and vg is 9.5%.  The recombination frequency between b and ...
									X h Y - nimitz126
									
... Both traits are displayed Ex. The ABO blood groups Neither IA nor IB are dominant is dominant over the other. Both are dominant over i. When both IA and IB are present they are codominant and the individual is type AB ...
                        	... Both traits are displayed Ex. The ABO blood groups Neither IA nor IB are dominant is dominant over the other. Both are dominant over i. When both IA and IB are present they are codominant and the individual is type AB ...
									this pdf
									
... it probably has something to do with the so-called grey area, as described above. An individual with 30 CAG repetitions has a longer Huntington gene than normal, but still this person does not develop the disease. It is possible that small errors are made in the copying of DNA for the formation of e ...
                        	... it probably has something to do with the so-called grey area, as described above. An individual with 30 CAG repetitions has a longer Huntington gene than normal, but still this person does not develop the disease. It is possible that small errors are made in the copying of DNA for the formation of e ...
									Chapter_9_HB_Patterns_of_Inheritance
									
... • Genetics is the science of heredity • A common genetic background will produce offspring with similar physical and behavioral traits – Purebred dogs show less variation than mutts – True-breeding individuals are useful in genetic research • Behavioral characteristics are also influenced by environ ...
                        	... • Genetics is the science of heredity • A common genetic background will produce offspring with similar physical and behavioral traits – Purebred dogs show less variation than mutts – True-breeding individuals are useful in genetic research • Behavioral characteristics are also influenced by environ ...
									Solid Tumour Section Uterus: Carcinoma of the cervix in Oncology and Haematology
									
... Preinvasive stage, detectable by cervical cytology, shows a peak incidence between 25 and 40 years; that of invasive cancer is 40-50 years, thus indicating that the preinvasive usually progresses to the invasive stage ...
                        	... Preinvasive stage, detectable by cervical cytology, shows a peak incidence between 25 and 40 years; that of invasive cancer is 40-50 years, thus indicating that the preinvasive usually progresses to the invasive stage ...
									Inferring Ancestral Chloroplast Genomes with Inverted
									
... Mutations in a genome consist of not only base pair level changes but also events that alter the chromosome structure, such as inversions, duplications or deletions [13]. Ancestral gene sequence inference has led to significant predictions of protein functional shift and positive selection [19]. For ...
                        	... Mutations in a genome consist of not only base pair level changes but also events that alter the chromosome structure, such as inversions, duplications or deletions [13]. Ancestral gene sequence inference has led to significant predictions of protein functional shift and positive selection [19]. For ...
									Answer Key
									
... the same pole. During anaphase I, a spindle fibre may attach to both homologous chromosomes and pull them to the same pole. This results in one cell having one too many chromosomes (called trisomy) or one too few chromosomes (called monosomy). 14. By looking at the homologous pairings in a karyotype ...
                        	... the same pole. During anaphase I, a spindle fibre may attach to both homologous chromosomes and pull them to the same pole. This results in one cell having one too many chromosomes (called trisomy) or one too few chromosomes (called monosomy). 14. By looking at the homologous pairings in a karyotype ...
									Nucleic Acids notes
									
... DNA strand (informational strand) 5’ ATG CCA GTA GGC CAC TTG TCA 3’ DNA strand (template strand) ...
                        	... DNA strand (informational strand) 5’ ATG CCA GTA GGC CAC TTG TCA 3’ DNA strand (template strand) ...
									Acquired vs. inherited Traits
									
... DNA, however amount of available water, carbon dioxide, and sunlight can influence this. Hair color: Encoded for by DNA but can be changed by chemicals or exposure to sunlight. Skin color: natural color encoded for by DNA but can easily be influenced by exposure to sunlight. ...
                        	... DNA, however amount of available water, carbon dioxide, and sunlight can influence this. Hair color: Encoded for by DNA but can be changed by chemicals or exposure to sunlight. Skin color: natural color encoded for by DNA but can easily be influenced by exposure to sunlight. ...
									Topic 6: Evolution – 6d. Hardy-Weinberg Lab
									
... Simulation 1: Begin by counting the number of students in the class and counting the genotypes in the class and then calculate the frequency of the alleles, A and a. Record this information on the Evidence Table. Each member will mate (exchange a card) with another member of the class. After the exc ...
                        	... Simulation 1: Begin by counting the number of students in the class and counting the genotypes in the class and then calculate the frequency of the alleles, A and a. Record this information on the Evidence Table. Each member will mate (exchange a card) with another member of the class. After the exc ...
									Disease-resistant genetically modified animals
									
... tools that enable the genetic nature of the desirable trait to be distinguished, a directed approach to the genetic improvement of livestock is possible. Sophisticated statistical and computing tools now enhance conventional genetic selection (35), although traits such as fertility and disease resis ...
                        	... tools that enable the genetic nature of the desirable trait to be distinguished, a directed approach to the genetic improvement of livestock is possible. Sophisticated statistical and computing tools now enhance conventional genetic selection (35), although traits such as fertility and disease resis ...
									Meiotic markers of gonad development in zebrafish
									
... Mechanism of sex determination unknown No sex chromosomes found Possible genetic sex determination influenced by environment ? Juvenile hermaphrodites with separate sexes in adults ...
                        	... Mechanism of sex determination unknown No sex chromosomes found Possible genetic sex determination influenced by environment ? Juvenile hermaphrodites with separate sexes in adults ...
									An introduction to the Cancer Genetics Unit
									
... you and other family members (referrals may be made for screening to be put in place) Possibly ask if a cancer diagnosis can be verified to help with the accuracy of your assessment (for example, ask if copies of death certificates can be obtained or arrange to get consent to allow us to see an indi ...
                        	... you and other family members (referrals may be made for screening to be put in place) Possibly ask if a cancer diagnosis can be verified to help with the accuracy of your assessment (for example, ask if copies of death certificates can be obtained or arrange to get consent to allow us to see an indi ...
									1 Sensitivity analysis We performed a detailed sensitivity analysis in
									
... such conditions, PRUNET was applied 10 times with a population size of 30, selection number of 15, and 100 iterations of the algorithm. The top 5 networks of each run (50 in total) were collected and used to compare the effect across the genes and biological examples. It is important to note here th ...
                        	... such conditions, PRUNET was applied 10 times with a population size of 30, selection number of 15, and 100 iterations of the algorithm. The top 5 networks of each run (50 in total) were collected and used to compare the effect across the genes and biological examples. It is important to note here th ...
									MS-SCI-LS-Unit 2 -- Chapter 5- Genetics-The
									
... d. Students know plant and animal cells contain many thousands of different genes and typically have two copies of every gene. The two copies (or alleles) of the gene may or may not be identical, and one may be dominant in determining the phenotype while the other is recessive. ...
                        	... d. Students know plant and animal cells contain many thousands of different genes and typically have two copies of every gene. The two copies (or alleles) of the gene may or may not be identical, and one may be dominant in determining the phenotype while the other is recessive. ...
									Kin selection, genomics and caste
									
... development of theory to predict how kin selection affects patterns of genetic variation. Of particular relevance for highly social species, such as social insects, is the case of antagonistic selection between castes [10], which occurs when distinct castes have different phenotypic optima for the s ...
                        	... development of theory to predict how kin selection affects patterns of genetic variation. Of particular relevance for highly social species, such as social insects, is the case of antagonistic selection between castes [10], which occurs when distinct castes have different phenotypic optima for the s ...
									Word Work File L_2.tmp
									
... A small amount of telomeric DNA fails to replicate each time the DNA replicates. No essential genetic information is lost. Telomeric DNA can be lengthened by a DNA replicating enzyme called telomerase. Telomerase molecules have a small RNA molecule together with the protein. Cells that produce telom ...
                        	... A small amount of telomeric DNA fails to replicate each time the DNA replicates. No essential genetic information is lost. Telomeric DNA can be lengthened by a DNA replicating enzyme called telomerase. Telomerase molecules have a small RNA molecule together with the protein. Cells that produce telom ...
									Chapter 14 – Mendel and the Gene Idea
									
... In the 20th century, geneticists have extended Mendelian principles not only to diverse organisms, but also to patterns of inheritance more complex than Mendel described. ...
                        	... In the 20th century, geneticists have extended Mendelian principles not only to diverse organisms, but also to patterns of inheritance more complex than Mendel described. ...
									Azadeh Hamid Reza
									
... 5’-noncoding region of bovine estrogen receptor α gene, the RFLP-SnaBI. Biochem. Genet. 2007, 45:255-262. [21] T. Szreder, and L. Zwierzchowski. Polymorphism within the bovine estrogen receptor-α gene 5’-region. J. Appl. Genet. 2004a, 45: 225-236. [22] T. Szreder, and L. Zwierzchowski. RFLP-TspRI po ...
                        	... 5’-noncoding region of bovine estrogen receptor α gene, the RFLP-SnaBI. Biochem. Genet. 2007, 45:255-262. [21] T. Szreder, and L. Zwierzchowski. Polymorphism within the bovine estrogen receptor-α gene 5’-region. J. Appl. Genet. 2004a, 45: 225-236. [22] T. Szreder, and L. Zwierzchowski. RFLP-TspRI po ...
									Smith, GF and Warren, ST: The biology of Down syndrome. Annals of the New York Academy of Science 450: 1-9 (1985).
									
... Therefore, it is not unlikely that for many genes, the presence of an extra copy would likewise be of little consequence. Thus the remaining genes must code for proteins (or RNA) that either have a major role in development by themselves or else are involved in gene regulation, thereby influencing o ...
                        	... Therefore, it is not unlikely that for many genes, the presence of an extra copy would likewise be of little consequence. Thus the remaining genes must code for proteins (or RNA) that either have a major role in development by themselves or else are involved in gene regulation, thereby influencing o ...
									Evo-Devo: The merging of Evolutionary and Developmental Biology
									
... Developmental control networks placed evolutionary constraints on the animal anatomies that evolved by natural selection ...
                        	... Developmental control networks placed evolutionary constraints on the animal anatomies that evolved by natural selection ...
									Recombination - Transformation
									
... The suppression of homologous recombination started outside of the SRY (Sex Reversal of Y) gene and spread to other regions in a rather spontaneous fashion, leading to the loss of genes and chromatin. It has been speculated that the cause of suppression is inversion on the Y-chromosome. When the hom ...
                        	... The suppression of homologous recombination started outside of the SRY (Sex Reversal of Y) gene and spread to other regions in a rather spontaneous fashion, leading to the loss of genes and chromatin. It has been speculated that the cause of suppression is inversion on the Y-chromosome. When the hom ...