Supplementary Material and Methods
... each sample was rescaled so that an individual sample’s sample adaptive threshold (SAT) (Additional File 1) was set to ± 0.1. For each tumor, gain then corresponds to a GISTIC log2ratio>0.1 and loss to < -0.1 in rescaled log2ratio. CNV masking was performed by matching BAC probes to CNV data for the ...
... each sample was rescaled so that an individual sample’s sample adaptive threshold (SAT) (Additional File 1) was set to ± 0.1. For each tumor, gain then corresponds to a GISTIC log2ratio>0.1 and loss to < -0.1 in rescaled log2ratio. CNV masking was performed by matching BAC probes to CNV data for the ...
Embryonic growth and the evolution of the mammalian Y
... with paternally expressed imprinted genes, in a species in which females are not obligately monogamous, a Y-linked sequence that can positively alter any of the above parameters could spread in a population even if it harms the prospects of other embryos. Such a selfish Y-linked gene could act as a ...
... with paternally expressed imprinted genes, in a species in which females are not obligately monogamous, a Y-linked sequence that can positively alter any of the above parameters could spread in a population even if it harms the prospects of other embryos. Such a selfish Y-linked gene could act as a ...
Chase, B. A., and Baker, B. S.
... that although i x and dsx mutants have highly similar either in homozygous, hemizygousor heteroallelic comeffects on the external morphology of diplo-X adults, binations, has a demonstrable effect on male courtship they have dissimilar effects on the diplo-Xnervous sysbehavior. Finallywe demonstrate ...
... that although i x and dsx mutants have highly similar either in homozygous, hemizygousor heteroallelic comeffects on the external morphology of diplo-X adults, binations, has a demonstrable effect on male courtship they have dissimilar effects on the diplo-Xnervous sysbehavior. Finallywe demonstrate ...
Developmental Systems Theory: A Search for Human Nature
... the processes of evolution, has a simple, if bleak, view of life: "You could consider a living organism as nothing more than an information channel, where it's transmitting its genome to its offspring, and the information stored in the channel is how to build a new channel" (Zimmer 23). This idea of ...
... the processes of evolution, has a simple, if bleak, view of life: "You could consider a living organism as nothing more than an information channel, where it's transmitting its genome to its offspring, and the information stored in the channel is how to build a new channel" (Zimmer 23). This idea of ...
Genes in conflict: the biology of selfish genetic elements
... by a linear hierarchy of alleles at the nuclear matA locus, with the “losing” mtDNA being actively degraded soon after gamete fusion (Kawano and Kuroiwa 1989, Meland et al. 1991). And, in many plant species mtDNA is either stripped from mitochondria or severely degraded during pollen maturation, pri ...
... by a linear hierarchy of alleles at the nuclear matA locus, with the “losing” mtDNA being actively degraded soon after gamete fusion (Kawano and Kuroiwa 1989, Meland et al. 1991). And, in many plant species mtDNA is either stripped from mitochondria or severely degraded during pollen maturation, pri ...
Microbial Ecology
... endophytes has been stimulated by their potential use for plant-growth promotion, antagonistic effects against plant pathogens, or biological nitrogen fixation for sustainable agriculture [13]. Although several graminaceous plants have been investigated for the occurrence and diversity of endophytic ...
... endophytes has been stimulated by their potential use for plant-growth promotion, antagonistic effects against plant pathogens, or biological nitrogen fixation for sustainable agriculture [13]. Although several graminaceous plants have been investigated for the occurrence and diversity of endophytic ...
lectureFeb27
... Transcriptional Regulation of the L-ara operon • Distinguish between positive and negative transcriptional regulation • Make predictions based on hypotheses • Infer protein function from mutant phenotype Pages 519-525 of textbook ...
... Transcriptional Regulation of the L-ara operon • Distinguish between positive and negative transcriptional regulation • Make predictions based on hypotheses • Infer protein function from mutant phenotype Pages 519-525 of textbook ...
Diagnosing Mitochondrial Disorder
... because he was the one who had the muscle biopsy performed, was then tested for several other genetic disorders commonly associated with Mito, including Prader-Willi and Fragile X. Once we were able to eliminate another primary diagnosis, we began testing to look for their specific type of Mitochond ...
... because he was the one who had the muscle biopsy performed, was then tested for several other genetic disorders commonly associated with Mito, including Prader-Willi and Fragile X. Once we were able to eliminate another primary diagnosis, we began testing to look for their specific type of Mitochond ...
SEX-LINKED INHERITANCE
... • Never passed from father to son. • Males are much more likely to be affected because they only need one copy of the mutant allele to express the phenotype. • Affected males get the disease from their mothers and all of their daughters are obligate carriers. • Sons of heterozygous females have a 50 ...
... • Never passed from father to son. • Males are much more likely to be affected because they only need one copy of the mutant allele to express the phenotype. • Affected males get the disease from their mothers and all of their daughters are obligate carriers. • Sons of heterozygous females have a 50 ...
CF Overview of CF Genotypin and NSQAP services
... The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. Use of trade names and commercial sources is for identification only and does not imply endorsement by the Division of Labora ...
... The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. Use of trade names and commercial sources is for identification only and does not imply endorsement by the Division of Labora ...
Gene conversion rapidly generates major histocompatibility complex
... Population bottlenecks can restrict variation at functional genes, reducing the ability of populations to adapt to new and changing environments. Understanding how populations generate adaptive genetic variation following bottlenecks is therefore central to evolutionary biology. Genes of the major h ...
... Population bottlenecks can restrict variation at functional genes, reducing the ability of populations to adapt to new and changing environments. Understanding how populations generate adaptive genetic variation following bottlenecks is therefore central to evolutionary biology. Genes of the major h ...
The Effects of Deleterious Mutations on Evolution at
... descendants of all other classes are ultimately destined for elimination. This is equivalent to saying that the effective population size Ne (Wright 1931) is equal to the number of breeding individuals in this “least-loaded” class and is necessarily much smaller than the number of breeding individua ...
... descendants of all other classes are ultimately destined for elimination. This is equivalent to saying that the effective population size Ne (Wright 1931) is equal to the number of breeding individuals in this “least-loaded” class and is necessarily much smaller than the number of breeding individua ...
simple patterns of inheritance
... time of conception, and that these seeds cause offspring to resemble their parents. This idea, known as pangenesis, influenced the thinking of scientists for many centuries. The first systematic studies of genetic crosses were carried out by the plant breeder Joseph Kolreuter between 1761 and 1766. ...
... time of conception, and that these seeds cause offspring to resemble their parents. This idea, known as pangenesis, influenced the thinking of scientists for many centuries. The first systematic studies of genetic crosses were carried out by the plant breeder Joseph Kolreuter between 1761 and 1766. ...
CLIN EXP RHEUM 28/4
... We greatly appreciate the interest shown by Brenol et al. for our data showing for first time that some interactions between NOS gene polymorphisms and HLA-DRB1 alleles confer and increased risk of developing cardiovascular events in patients with rheumatoid arthritis (RA) (1). As pointed out by Dr B ...
... We greatly appreciate the interest shown by Brenol et al. for our data showing for first time that some interactions between NOS gene polymorphisms and HLA-DRB1 alleles confer and increased risk of developing cardiovascular events in patients with rheumatoid arthritis (RA) (1). As pointed out by Dr B ...
Biology Summer Packet Major themes covered in this packet
... 8. All life is related and descended from a common ancestor. 9. The universe began about 15 billion years ago. 10. New tennis balls bounce higher than old tennis balls. 11. Caffeine raises blood pressure. ...
... 8. All life is related and descended from a common ancestor. 9. The universe began about 15 billion years ago. 10. New tennis balls bounce higher than old tennis balls. 11. Caffeine raises blood pressure. ...
Creation/Evolution - Geoscience Research Institute
... Any gene with two or more alleles is said to have multiple alleles Mendel worked with only two allele systems, but variations from the kind of results he obtained occur when more than two alleles are involved Note that while individuals cannot have more than two alleles for a given gene, populations ...
... Any gene with two or more alleles is said to have multiple alleles Mendel worked with only two allele systems, but variations from the kind of results he obtained occur when more than two alleles are involved Note that while individuals cannot have more than two alleles for a given gene, populations ...
Chromosomes and Cell Reproduction
... distribution of homologous chromosomes during meiosis. Each of the 23 pairs of chromosomes segregates (separates) independently. Thus, 223 (about 8 million) gametes with different gene combinations can be produced from one original cell. ...
... distribution of homologous chromosomes during meiosis. Each of the 23 pairs of chromosomes segregates (separates) independently. Thus, 223 (about 8 million) gametes with different gene combinations can be produced from one original cell. ...
38891
... • Our general assumption is guilt by association: i.e. genes with similar expression patterns are more likely to participate in the same biological process. • Therefore, we can exploit the Gene Ontology to assess our clusters: ...
... • Our general assumption is guilt by association: i.e. genes with similar expression patterns are more likely to participate in the same biological process. • Therefore, we can exploit the Gene Ontology to assess our clusters: ...
Exercise 1 - EuPathDB Workshop
... 1.5 More BLASTing in EuPathDB (optional). Note: for this exercise use http://www.eupathdb.org a. The first thing we will need to do is get a sequence to use for BLAST. Search for the keyword "dihydrofolate" (without quotations). (Hint: use the Gene Text Search on the upper right hand side of the EuP ...
... 1.5 More BLASTing in EuPathDB (optional). Note: for this exercise use http://www.eupathdb.org a. The first thing we will need to do is get a sequence to use for BLAST. Search for the keyword "dihydrofolate" (without quotations). (Hint: use the Gene Text Search on the upper right hand side of the EuP ...
ppt
... A. Gene Selection 1. Meiotic Drive: In some organisms, the heterozygote produces a preponderance of one gamete type - this is called "segregation distortion". This gene is at a selective advantage over other genes at this locus. Of course, as it increases in frequency and more organisms are homozygo ...
... A. Gene Selection 1. Meiotic Drive: In some organisms, the heterozygote produces a preponderance of one gamete type - this is called "segregation distortion". This gene is at a selective advantage over other genes at this locus. Of course, as it increases in frequency and more organisms are homozygo ...
- Holterman
... Heterozygous, Punnett Square (be able to use one), Analysis; go over problems done for homework; Multiple Alleles: fly example (eye colour), co-dominance, incomplete dominance; use notes as reference Sex-linked Traits: carriers, sex-linked disorders (i.e., hemophilia), X and Y chromosomes; use notes ...
... Heterozygous, Punnett Square (be able to use one), Analysis; go over problems done for homework; Multiple Alleles: fly example (eye colour), co-dominance, incomplete dominance; use notes as reference Sex-linked Traits: carriers, sex-linked disorders (i.e., hemophilia), X and Y chromosomes; use notes ...
Designer Babies and 21st Century Cures
... for applying cloning techniques to stem-cell science in order to find cures for the world’s most devastating genetic diseases and disorders, such as Parkinson’s and Hodgkin’s diseases. On a conceptual level, the process of cloning is really not very complicated. DNA is harvested from an adult cell ( ...
... for applying cloning techniques to stem-cell science in order to find cures for the world’s most devastating genetic diseases and disorders, such as Parkinson’s and Hodgkin’s diseases. On a conceptual level, the process of cloning is really not very complicated. DNA is harvested from an adult cell ( ...
Leukaemia Section del(11q) in non-Hodgkin's lymphoma (NHL) Atlas of Genetics and Cytogenetics
... an approximate 10% incidence of 11q deletion among other histologic subsets of B-NHL; among diffuse large B-cell lymphoma the 11q- chromosome shows a preferential association with the immunoblastic variant; sensitive molecular cytogenetic methods may show 5070% of T-cell prolymphocytic leukemia to c ...
... an approximate 10% incidence of 11q deletion among other histologic subsets of B-NHL; among diffuse large B-cell lymphoma the 11q- chromosome shows a preferential association with the immunoblastic variant; sensitive molecular cytogenetic methods may show 5070% of T-cell prolymphocytic leukemia to c ...