Elyse Coolidge
... Of the 18 Oprm SNPs examined, the A118G SNP was included. Neither this SNP, nor any of the other 35 SNPs in Oprm and Oprd1 were found to be associated with alcohol, illicit drug, or opioid dependence. However, three SNPs on the Penk gene and two SNPs on the POMC gene were found to be associated with ...
... Of the 18 Oprm SNPs examined, the A118G SNP was included. Neither this SNP, nor any of the other 35 SNPs in Oprm and Oprd1 were found to be associated with alcohol, illicit drug, or opioid dependence. However, three SNPs on the Penk gene and two SNPs on the POMC gene were found to be associated with ...
Newsletter February 2016
... A DNA test is available for the merle gene which dilutes random parts of the coat colour to a lighter shade, black to gray or blue, brown to lighter patches. The merled patches have irregular edges and can be anywhere on the head, body and legs resulting in the merle coat pattern. Merle can also aff ...
... A DNA test is available for the merle gene which dilutes random parts of the coat colour to a lighter shade, black to gray or blue, brown to lighter patches. The merled patches have irregular edges and can be anywhere on the head, body and legs resulting in the merle coat pattern. Merle can also aff ...
The Optimal Discovery Procedure II: Applications to Comparative
... A microarray measures the abundance of mRNA transcripts of thousands of genes from a single biological sample (1, 2). Of much recent interest has been the problem of identifying genes that are differentially expressed across varying biological conditions based on microarray data (3). It is now possi ...
... A microarray measures the abundance of mRNA transcripts of thousands of genes from a single biological sample (1, 2). Of much recent interest has been the problem of identifying genes that are differentially expressed across varying biological conditions based on microarray data (3). It is now possi ...
CentrosomeDB: a new generation of the
... CentrosomeDB navigation is similar to the previous version and it is self-explanatory and intuitive. Therefore to better illustrate its use and potential we focus on one of the new features: the PPIs. The work of Fogeron et al. (31), aimed to discover new target molecules that are deregulated in can ...
... CentrosomeDB navigation is similar to the previous version and it is self-explanatory and intuitive. Therefore to better illustrate its use and potential we focus on one of the new features: the PPIs. The work of Fogeron et al. (31), aimed to discover new target molecules that are deregulated in can ...
Systems of mating
... • Inbreeding Can Be Measured by Deviations from Random Mating in a Deme (either the tendency to preferentially mate with relatives or to preferentially avoid mating with relatives relative to random mating) ...
... • Inbreeding Can Be Measured by Deviations from Random Mating in a Deme (either the tendency to preferentially mate with relatives or to preferentially avoid mating with relatives relative to random mating) ...
Genetic and experimental studies on a pigment
... basis of the Pale phenotype is a reduction in the density of melanosomes within' melanophores. The Pale phenotype does not lead to an alteration in melanophore number, size or shape, and melanosomes were rather evenly dispersed throughout P°-/Pa melanophores as they were in P/P melanophores. Possibl ...
... basis of the Pale phenotype is a reduction in the density of melanosomes within' melanophores. The Pale phenotype does not lead to an alteration in melanophore number, size or shape, and melanosomes were rather evenly dispersed throughout P°-/Pa melanophores as they were in P/P melanophores. Possibl ...
Improved production of poly-γ-glutamate by newly Bacillus subtilis
... The D-glutamate content was over 50% in every γ-PGA produced under the conditions used, suggesting that the bacterium possesses a synthetic pathway to produce D-glutamate, the main precursor of γ-PGA, from L-glutamate.To obtain a clue as to the nature of the D-glutamate synthetic pathway in B. subti ...
... The D-glutamate content was over 50% in every γ-PGA produced under the conditions used, suggesting that the bacterium possesses a synthetic pathway to produce D-glutamate, the main precursor of γ-PGA, from L-glutamate.To obtain a clue as to the nature of the D-glutamate synthetic pathway in B. subti ...
BIO 127
... Objective 6. Patterns of gene inheritance (Chapt. 23) and Patterns of chromosome inheritance (Chapt. 24) Students should be able to: 1. describe concepts of Mendelian genetics 2. explain laws of segregation and independent assortment 3. state Mendelian principles in inheritance human traits 4. defin ...
... Objective 6. Patterns of gene inheritance (Chapt. 23) and Patterns of chromosome inheritance (Chapt. 24) Students should be able to: 1. describe concepts of Mendelian genetics 2. explain laws of segregation and independent assortment 3. state Mendelian principles in inheritance human traits 4. defin ...
Bruce Wallace Biotechnology Lab Program Student Guide 5th
... the plasmids from those that do not. If a bacterium carries a plasmid with an antibiotic resistant gene, the bacterium will be able to grow and reproduce in the presence of that antibiotic; those bacteria without the plasmid will not be able to grow. Thus, antibiotics can be used to select bacteria ...
... the plasmids from those that do not. If a bacterium carries a plasmid with an antibiotic resistant gene, the bacterium will be able to grow and reproduce in the presence of that antibiotic; those bacteria without the plasmid will not be able to grow. Thus, antibiotics can be used to select bacteria ...
On the genetics of hypodontia and microdontia
... parents, on the other hand, suggests two different mutations. In this family these mutations then mutually influence the penetrance of each other, causing the observed aggravation of the condition. This is most easy to envisage if the predisposing genes are different allelic mutations at the same ge ...
... parents, on the other hand, suggests two different mutations. In this family these mutations then mutually influence the penetrance of each other, causing the observed aggravation of the condition. This is most easy to envisage if the predisposing genes are different allelic mutations at the same ge ...
Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting Open Access
... Background: Genomic imprinting causes parent-of-origin specific gene expression by differential epigenetic modifications between two parental genomes. We previously reported that there is no evidence of genomic imprinting of CDKN1C in the KCNQ1 domain in the placenta of an Australian marsupial, the ...
... Background: Genomic imprinting causes parent-of-origin specific gene expression by differential epigenetic modifications between two parental genomes. We previously reported that there is no evidence of genomic imprinting of CDKN1C in the KCNQ1 domain in the placenta of an Australian marsupial, the ...
Malate dehydrogenase and glucose-6
... and stained within 1-2 min of incubation with the reaction mixture. Although 3 groups were delineated separately by both MDH and G6PDH, both enzymes should be used at present to cluster isolates. A. actinomycetemcomitans grows poorly, and colonies sometimes adhere strongly to the agar making the har ...
... and stained within 1-2 min of incubation with the reaction mixture. Although 3 groups were delineated separately by both MDH and G6PDH, both enzymes should be used at present to cluster isolates. A. actinomycetemcomitans grows poorly, and colonies sometimes adhere strongly to the agar making the har ...
Epidemiologic and Genetic Approaches in the
... required to detect an interaction greater than 4 (with 80 percent power). Recently, this study design has been used in pharmacogenetic studies to evaluate putative associations of susceptibility genes involved in metabolism of carcinogens and cancers taking into account carcinogen exposure. For exam ...
... required to detect an interaction greater than 4 (with 80 percent power). Recently, this study design has been used in pharmacogenetic studies to evaluate putative associations of susceptibility genes involved in metabolism of carcinogens and cancers taking into account carcinogen exposure. For exam ...
Sex linked inheritance, sex linkage in Drosophila and man, XO, XY
... Analysis of inheritance pattern of phenotypic characters in a pedigree is called pedigree analysis. Propositus/Proband: A member of a family who first comes to the attention of a geneticist. The investigator then traces the history of the phenotype in the propositus back through the history of the f ...
... Analysis of inheritance pattern of phenotypic characters in a pedigree is called pedigree analysis. Propositus/Proband: A member of a family who first comes to the attention of a geneticist. The investigator then traces the history of the phenotype in the propositus back through the history of the f ...
Keratins and skin disorders
... situations, it will be more useful to consider the keratin disorders as a cluster of hereditary defects involving different members of a large closely-related family of structural genes, rather than a collection of very rare ‘orphan’ diseases. Another message to emerge from increasing documentation ...
... situations, it will be more useful to consider the keratin disorders as a cluster of hereditary defects involving different members of a large closely-related family of structural genes, rather than a collection of very rare ‘orphan’ diseases. Another message to emerge from increasing documentation ...
7.27 Spring 2006 PROBLEM SET DUE MAY 12, 2006 1. A couple
... heart defect and does not survive to term. A karyotype is performed on both the mother and the father. The father is discovered to carry a balanced translocation between chromosomes 8 and 21 while the mother’s karyotype is normal. In their next pregnancy what possible outcomes could occur? Draw each ...
... heart defect and does not survive to term. A karyotype is performed on both the mother and the father. The father is discovered to carry a balanced translocation between chromosomes 8 and 21 while the mother’s karyotype is normal. In their next pregnancy what possible outcomes could occur? Draw each ...
Analogous structure
... have long snouts that allow their jaws to open wide. However, they evolved in completely different ways. What type of structure is ...
... have long snouts that allow their jaws to open wide. However, they evolved in completely different ways. What type of structure is ...
Cooperative Effects of Bacterial Mutations Affecting A N Gene
... another class of mutations, nus. Nus mutations have previously been shown to inhibit the expression of the N gene product of h, and the experiments reported here suggest that Snu mutations add to this inhibitory effect. One Snu mutation, Snu-9, was shown to cause bacterial growth to be temperaturese ...
... another class of mutations, nus. Nus mutations have previously been shown to inhibit the expression of the N gene product of h, and the experiments reported here suggest that Snu mutations add to this inhibitory effect. One Snu mutation, Snu-9, was shown to cause bacterial growth to be temperaturese ...
X chromosome inactivation- Review
... Xist is expressed from both X chromosomes in female Xist encodes 15 kb polyadenylated untranslated RNA that is unstable Xist is gene located within Xic ...
... Xist is expressed from both X chromosomes in female Xist encodes 15 kb polyadenylated untranslated RNA that is unstable Xist is gene located within Xic ...
The Plant Cell
... MicroRNAs (miRNAs) are noncoding RNAs of 21 nucleotides in length that have been identified in both animals and plants (Lagos-Quintana et al., 2001, 2002; Lau et al., 2001; Lee and Ambros, 2001; Llave et al., 2002a; Mourelatos et al., 2002; Park et al., 2002; Reinhart et al., 2002). They are proces ...
... MicroRNAs (miRNAs) are noncoding RNAs of 21 nucleotides in length that have been identified in both animals and plants (Lagos-Quintana et al., 2001, 2002; Lau et al., 2001; Lee and Ambros, 2001; Llave et al., 2002a; Mourelatos et al., 2002; Park et al., 2002; Reinhart et al., 2002). They are proces ...
December 8, 2006 - Brandeis University
... Homologs of human genes involved in life-threatening diseases are useful to study when trying to understand the function or regulation of their mammalian counterparts. Experiments that purposely mutate genes to observe the ensuing effects, while not always possible in humans, are uncontroversial whe ...
... Homologs of human genes involved in life-threatening diseases are useful to study when trying to understand the function or regulation of their mammalian counterparts. Experiments that purposely mutate genes to observe the ensuing effects, while not always possible in humans, are uncontroversial whe ...
Five components of the ethylene-response pathway
... insensitivity to a near wild-type response. This variability was observed even when wei3 plants with clear ethylene-insensitive roots were selected and propagated for several generations. Although these results can be explained by low penetrance of the mutant phenotype, it is also possible that the ...
... insensitivity to a near wild-type response. This variability was observed even when wei3 plants with clear ethylene-insensitive roots were selected and propagated for several generations. Although these results can be explained by low penetrance of the mutant phenotype, it is also possible that the ...
Gene Section CDA (Cytidine Deaminase) Atlas of Genetics and Cytogenetics
... (Lys27Gln) and 208G>A (Ala70Thr), have been found in the human CDA gene (Yue et al., 2003). Ethnic differences in the minor allele frequencies of these variations have been reported. The 79A>C (Lys27Gln) was found at 0.30-0.36 frequencies in Caucasians, at 0.20-0.21 in Japanese and at 0.04-0.10 in A ...
... (Lys27Gln) and 208G>A (Ala70Thr), have been found in the human CDA gene (Yue et al., 2003). Ethnic differences in the minor allele frequencies of these variations have been reported. The 79A>C (Lys27Gln) was found at 0.30-0.36 frequencies in Caucasians, at 0.20-0.21 in Japanese and at 0.04-0.10 in A ...
Section D - Prokaryotic and Eukaryotic Chromosome Structure
... • Some genes contain terminator sequences requiring an accessory factor, the rho protein (ρ) to mediated transcription termination. • Rho binds to specific sites in the singlestranded RNA. • Rho protein (hexameric protein) binds to certain RNA structure (72bp) • Rho hydrolyses ATP and moves along th ...
... • Some genes contain terminator sequences requiring an accessory factor, the rho protein (ρ) to mediated transcription termination. • Rho binds to specific sites in the singlestranded RNA. • Rho protein (hexameric protein) binds to certain RNA structure (72bp) • Rho hydrolyses ATP and moves along th ...